anti-Human ROCK1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended ROCK1 Antibody (supplied by: Log in to see )

Antigen
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) Antibodies
  • LOC100229794
  • CG9774
  • DROK
  • DRhk
  • DRok
  • Dmel\\CG9774
  • Drok
  • ROCK
  • ROCK-1
  • ROCK1
  • ROK
  • ROKalpha/beta
  • Rhk
  • RhoK
  • Rock
  • Rok
  • dROK
  • dRok
  • drok
  • 1110055K06Rik
  • Rock-I
  • P160Rock
  • ROCK-I
  • P160ROCK
  • p160ROCK
  • Rho-associated, coiled-coil containing protein kinase 1
  • Rho-kinase
  • Rho-associated coiled-coil containing protein kinase 1
  • ROCK1
  • LOC100229794
  • rok
  • Rock1
  • rock1
Epitope
AA 980-1030
39
28
27
24
21
14
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
195
143
132
25
21
20
6
5
4
2
1
Host
Rabbit
114
83
Clonality
Polyclonal
Conjugate
This ROCK1 antibody is un-conjugated
8
7
7
7
6
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
154
45
35
34
28
24
24
16
2
2
1
1
1
1
Options
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Catalog No. ABIN738636
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN707771 IF (p) IHC (p) WB Rabbit IgG pThr455, pSer456 Log in to see Polyclonal 2
1 ABIN2806062 IF (p) Alexa Fluor 594 Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN2806063 IF (p) Alexa Fluor 594 Rabbit IgG AA 440-465, Ser456, pThr455 Log in to see Polyclonal
1 ABIN738640 IF (p) Cy5 Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN738639 IF (p) Cy3 Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN738641 IF (p) Cy5.5 Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN738642 IF (p) Cy7 Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN738643 IF (p) FITC Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN707775 IF (p) Cy5 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN707778 IF (p) FITC Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN707776 IF (p) Cy5.5 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN707774 IF (p) Cy3 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN707777 IF (p) Cy7 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN876251 IF (p) Alexa Fluor 488 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN876252 IF (p) Alexa Fluor 647 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN876249 IF (p) Alexa Fluor 350 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN876250 IF (p) Alexa Fluor 555 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
1 ABIN913896 IF (p) Alexa Fluor 647 Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN913898 IF (p) Alexa Fluor 350 Rabbit IgG AA 980-1030 Log in to see Polyclonal
1 ABIN913900 IF (p) Alexa Fluor 555 Rabbit IgG AA 980-1030 Log in to see Polyclonal

General

Antigen rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) Antibodies
Epitope AA 980-1030
(39), (28), (27), (24), (21), (14), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(195), (143), (132), (25), (21), (20), (6), (5), (4), (2), (1)
Host Rabbit
(114), (83)
Clonality
Polyclonal
Conjugate This ROCK1 antibody is un-conjugated
(8), (7), (7), (7), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(154), (45), (35), (34), (28), (24), (24), (16), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-ROCK1 Antibody

Target Details ROCK1 Application Details Handling ProductDetails: References for anti-ROCK1 antibody (ABIN738636) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human ROCK1
Isotype IgG

Target Details ROCK1

Product Details anti-ROCK1 Antibody Application Details Handling ProductDetails: References for anti-ROCK1 antibody (ABIN738636) Images back to top
Antigen
Alternative Name Rock1 (ROCK1 Antibody Abstract)
Background

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. Acts as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Required for centrosome positioning and centrosome-dependent exit from mitosis. Plays a role in terminal erythroid differentiation. May regulate closure of the eyelids and ventral body wall by inducing the assembly of actomyosin bundles. Promotes keratinocyte terminal differentiation. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.

Subcellular location: Cytoplasm

Synonyms: ROCK-I, P16ROCK, Rho-associated protein kinase 1, Renal carcinoma antigen NY-REN-35, Rho-associated, coiled-coil-containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase I, p16 ROCK-1, ROCK1

Gene ID 6093
UniProt Q13464
Research Area Cancer, Cell Cycle, Cytoskeleton, Microfilaments, Apoptosis/Necrosis, Signaling
Pathways Microtubule Dynamics, WNT Signaling, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling

Application Details

Product Details anti-ROCK1 Antibody Target Details ROCK1 Handling ProductDetails: References for anti-ROCK1 antibody (ABIN738636) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details ProductDetails: References for anti-ROCK1 antibody (ABIN738636) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-ROCK1 antibody (ABIN738636)

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details Handling Images back to top
Product cited in:

Wang, Zhang, Wang, Zhang, Mao, Zhuang, Tang, Luo, Zhou, Zhang: "Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 7, pp. 1447-56, 2013 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Images

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details Handling ProductDetails: References for anti-ROCK1 antibody (ABIN738636) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 980-1030) antibody (ABIN738636) Formalin-fixed and paraffin embedded human esophageal carcinoma labeled with Anti-ROC...
Immunohistochemistry (IHC) image for anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 980-1030) antibody (ABIN738636) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-ROCK1 Pol...
Immunohistochemistry (IHC) image for anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 980-1030) antibody (ABIN738636) Formalin-fixed and paraffin embedded rat heart labeled with Anti-ROCK1 Polyclonal Ant...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 980-1030) antibody (ABIN738636) Formalin-fixed and paraffin embedded human esophageal carcinoma labeled with Anti-ROC...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 980-1030) antibody (ABIN738636) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-ROCK1 Pol...