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anti-Human ROCK1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended ROCK1 Antibody (supplied by: Log in to see )

Antigen
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) Antibodies
  • 1110055K06Rik
  • CG9774
  • Dmel\\CG9774
  • DRhk
  • dRok
  • drok
  • Drok
  • DROK
  • DRok
  • dROK
  • LOC100229794
  • P160ROCK
  • P160Rock
  • p160ROCK
  • Rhk
  • RhoK
  • ROCK
  • Rock
  • ROCK-1
  • ROCK-I
  • Rock-I
  • ROCK1
  • ROK
  • Rok
  • ROKalpha/beta
Epitope
pThr455, pSer456
28
24
23
21
15
13
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
142
98
94
22
20
20
3
2
2
1
1
Host
Rabbit
105
40
Clonality
Polyclonal
Conjugate
This ROCK1 antibody is un-conjugated
4
4
4
4
4
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
106
31
31
21
18
17
10
9
2
1
1
1
1
Supplier
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Catalog No. ABIN707771
$ 291.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008767248 ABIN738636 IF (p) IHC (p) WB Rabbit IgG AA 980-1030 Log in to see Polyclonal 1
0.0008767248 ABIN913898 IF (p) Alexa Fluor 350 Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008767248 ABIN913899 IF (p) Alexa Fluor 488 Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008767248 ABIN913896 IF (p) Alexa Fluor 647 Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008767248 ABIN913900 IF (p) Alexa Fluor 555 Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008767248 ABIN876250 IF (p) Alexa Fluor 555 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008767248 ABIN876252 IF (p) Alexa Fluor 647 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008767248 ABIN876249 IF (p) Alexa Fluor 350 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008767248 ABIN876251 IF (p) Alexa Fluor 488 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008767248 ABIN707774 IF (p) Cy3 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008767248 ABIN707777 IF (p) Cy7 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008767248 ABIN707776 IF (p) Cy5.5 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008767248 ABIN707775 IF (p) Cy5 Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008767248 ABIN707778 IF (p) FITC Rabbit IgG pThr455, pSer456 Log in to see Polyclonal
0.0008767248 ABIN738639 IF (p) Cy3 Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008767248 ABIN738640 IF (p) Cy5 Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008767248 ABIN738643 IF (p) FITC Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008767248 ABIN738642 IF (p) Cy7 Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008767248 ABIN738641 IF (p) Cy5.5 Rabbit IgG AA 980-1030 Log in to see Polyclonal
0.0008767248 ABIN2806062 IF (p) Alexa Fluor 594 Rabbit IgG AA 980-1030 Log in to see Polyclonal

Top referenced anti-ROCK1 antibody for Immunofluorescence (Paraffin-embedded Sections)

  • Human Polyclonal ROCK1 Primary Antibody for IF (p), IHC (p) - ABIN707771 (2 Publications): Wang, Zhang, Wang, Zhang, Mao, Zhuang, Tang, Luo, Zhou, Zhang: Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway. in The international journal of biochemistry & cell biology 2013 (PubMed)

Similar anti-ROCK1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 17 Antibodies 17 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 1 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 6 Antibodies 7 Antibodies
Immunofluorescence (IF) 10 Antibodies 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 32 Antibodies 32 Antibodies
Immunohistochemistry (IHC) 7 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 60 Antibodies

General

Antigen rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) Antibodies
Epitope pThr455, pSer456
(28), (24), (23), (21), (15), (13), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(142), (98), (94), (22), (20), (20), (3), (2), (2), (1), (1)
Host Rabbit
(105), (40)
Clonality
Polyclonal
Conjugate This ROCK1 antibody is un-conjugated
(4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(106), (31), (31), (21), (18), (17), (10), (9), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-ROCK1 Antibody

Target Details ROCK1 Application Details Handling References for anti-ROCK1 Antibody (ABIN707771) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human ROCK1 around the phosphorylation site of Thr455/Ser456
Isotype IgG

Target Details ROCK1

Product Details anti-ROCK1 Antibody Application Details Handling References for anti-ROCK1 Antibody (ABIN707771) Images back to top
Antigen
Alternative Name Rock1 (ROCK1 Antibody Abstract)
Background

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. Acts as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Required for centrosome positioning and centrosome-dependent exit from mitosis. Plays a role in terminal erythroid differentiation. May regulate closure of the eyelids and ventral body wall by inducing the assembly of actomyosin bundles. Promotes keratinocyte terminal differentiation. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.


Synonyms: ROCK-I, P16ROCK, Rho-associated protein kinase 1, Renal carcinoma antigen NY-REN-35, Rho-associated, coiled-coil-containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase I, p16 ROCK-1, ROCK1
Gene ID 6093
UniProt Q13464
Research Area Cancer, Cell Cycle, Cytoskeleton, Microfilaments, Apoptosis/Necrosis, Signaling
Pathways Microtubule Dynamics, WNT Signaling

Application Details

Product Details anti-ROCK1 Antibody Target Details ROCK1 Handling References for anti-ROCK1 Antibody (ABIN707771) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details References for anti-ROCK1 Antibody (ABIN707771) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-ROCK1 Antibody (ABIN707771)

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details Handling Images back to top
Product cited in:

Lin, Chang, Chen, Shih: "RhoA/ROCK1 regulates Avian Reovirus S1133-induced switch from autophagy to apoptosis." in: BMC veterinary research, Vol. 11, pp. 103, 2015

Wang, Zhang, Wang, Zhang, Mao, Zhuang, Tang, Luo, Zhou, Zhang: "Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 7, pp. 1447-56, 2013

Images

Product Details anti-ROCK1 Antibody Target Details ROCK1 Application Details Handling References for anti-ROCK1 Antibody (ABIN707771) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-ROCK1 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 1) (pThr455) (ABIN707771) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-phospho-R...
Immunohistochemistry (IHC) image for anti-ROCK1 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 1) (pThr455) (ABIN707771) Formalin-fixed and paraffin embedded rat heart labeled with Anti-phospho-ROCK1(Thr455...