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Browse our ROCK1 (ROCK1) ELISA Kits

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rho-Associated, Coiled-Coil Containing Protein Kinase 1 ELISA Kits (ROCK1)
On are 3 rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) ELISA Kits from 3 different suppliers available. Additionally we are shipping ROCK1 Antibodies (150) and ROCK1 Proteins (8) and many more products for this protein. A total of 166 ROCK1 products are currently listed.
1110055K06Rik, CG9774, Dmel\\CG9774, DRhk, drok, LOC100229794, p160ROCK, Rhk, RhoK, Rock, ROCK-1, ROCK-I, ROCK1, Rok, ROKalpha/beta
list all ELISA KIts Gene Name GeneID UniProt
Mouse ROCK1 ROCK1 19877 P70335
ROCK1 81762 Q63644
Human ROCK1 ROCK1 6093 Q13464

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ROCK1 (ROCK1) ELISA Kits by Reactivity

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Fruit Fly (Drosophila melanogaster) rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) interaction partners

  1. Loss of DRok function in tendon cells results in mis (show AMH ELISA Kits)-orientation of tendon cell extensions and abnormal accumulation of Thrombospondin and betaPS-integrin, which may cause abnormal myotendinous (show TNC ELISA Kits) junction formation and muscle morphogenesis.

  2. model in which Rok-induced phosphorylation of residues within the basic region mediates the activation of FHOD1 (show FHOD1 ELISA Kits) homolog Knittrig in controlling macrophage migration

  3. Atonal and EGFR (show EGFR ELISA Kits) signalling orchestrate rok- and Drak-dependent adherens junction remodelling during ommatidia morphogenesis.

  4. The structure of Shrm (show SHROOM3 ELISA Kits) domain 2 (SD2), which mediates the interaction with Rock and is required for Shrm (show SHROOM3 ELISA Kits) function, is reported.

  5. Data show that that Drak broadly promotes proper morphogenesis of epithelial tissues during development, and Drak activity is largely redundant with that of the Drosophila ROCK orthologue, Rok.

  6. CD44 (show CD44 ELISA Kits) interaction with p115RhoGEF (show ARHGEF1 ELISA Kits) and ROK plays a pivotal role in promoting Gab-1 phosphorylation leading to Gab-1.PI 3 (show PI3 ELISA Kits)-kinase membrane localization, AKT (show AKT1 ELISA Kits) signaling, and cytokine (M-CSF (show CSF1R ELISA Kits)) production during HA-mediated breast cancer progression

  7. Drok and Drosophila Lim (show ZYX ELISA Kits)-kinase interact in the developing nervous system

  8. DRok is required for tissue morphogenesis in diverse compartments of the egg chamber during oogenesis

  9. activation of RhoA/ROCK and PI3K/Akt plays a pivotal role in leptin signaling, leading to the development of VSMC hypertrophy through a mechanism involving altered actin dynamics

  10. In parallel to regulation of crb RNA and protein, Rho1 activity also signals through Rho-kinase (Rok) to induce apical constriction and cell shape change during invagination of salivary gland.

Mouse (Murine) rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) interaction partners

  1. that reduction of ROCK1 diminishes amyloid-beta levels by enhancing Amyloid beta-Protein Precursor protein degradation

  2. ANXA1 (show ANXA1 ELISA Kits) restores Abeta42-induced blood brain barrier disruption through inhibition of RhoA (show RHOA ELISA Kits)-ROCK signaling pathway

  3. the cross-talk between canonical and non-canonical signaling pathways of Wnt3A (show WNT3A ELISA Kits), which induces GSK-3beta phosphorylation and beta-catenin (show CTNNB1 ELISA Kits) accumulation through RhoA (show RHOA ELISA Kits) and ROCK activation.

  4. Inhibition of ROCK1 largely blocked Endothelial-to-mesenchymal transition and the increase in endothelial permeability under this high-glucose condition, but overexpression of ROCK1 induced these changes.

  5. While the loss of either Rock1 or Rock2 (show ROCK2 ELISA Kits) had no negative impact on tumorigenesis in mouse models of non-small cell lung cancer and melanoma, loss of both blocked tumor formation, as no tumors arise in which both Rock1 and Rock2 (show ROCK2 ELISA Kits) have been genetically deleted.

  6. Fyn (show FYN ELISA Kits) mediates high glucose-induced actin cytoskeleton remodeling of podocytes via promoting ROCK activation and paxillin (show PXN ELISA Kits) phosphorylation

  7. YQFM ameliorates the OGD-induced brain microvascular endothelial cell barrier disruption associated with the NF-kappaB/p65 and ROCK1/MLC signaling pathways.

  8. Extracellular vesicle-encapsulated caspase-3 (show CASP3 ELISA Kits) was largely responsible for the alveolar macrophage activation via the ROCK1 pathway.

  9. In experimental autoimmune encephalomyelitis (EAE), ROCK activity was also increased in serum, spleen, brain and spinal cord. Neuron injury with scratch and TNF-alpha (show TNF ELISA Kits) stimulation induced the up-regulation of ROCK activity.

  10. indicates that the up-regulation of ROCK1 activity in RhoA (show RHOA ELISA Kits)-deleted macrophages and macrophage phenotype/polarity are dependent on non-apoptotic Caspase-3 (show CASP3 ELISA Kits)

Human rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) interaction partners

  1. BCR-ABL-dependent ROCK, but not TK, is involved in CD1d downregulation. We propose that ROCK, which is most likely activated by the DH/PH domain of BCR-ABL, mediates iNKT-cell immune subversion in chronic myeloid leukaemia (CML) patients by downregulating CD1d expression on CML mDCs.

  2. that reduction of ROCK1 diminishes amyloid-beta levels by enhancing Amyloid beta-Protein Precursor protein degradation

  3. Silencing Drp1 (show CRMP1 ELISA Kits) inhibits glioma cells proliferation and invasion by RHOA (show RHOA ELISA Kits)/ ROCK1 pathway.

  4. RhoB and ROCK play a key role in preeclampsia.

  5. We successfully identified a novel pathway via which SIN exerted antioxidative and renal protective functions, and provided a molecular basis for potential SIN applications in treating DN vascular disorders.

  6. The results of the present study indicate that miR126 inhibits RCC (show XRCC1 ELISA Kits) cell proliferation, migration and invasion by downregulating ROCK1.

  7. ROCK1 gene and ROCK protein expressions may contribute to the development of MCL (show FH ELISA Kits).

  8. miR (show MLXIP ELISA Kits)-214-5p was identified as a new tumor suppressor, which directly targeted ROCK1 and suppressed proliferation of human OS cells.

  9. vThese results suggest that ROCK may be important in IL-1 (show IL1A ELISA Kits)-induced signaling through MKK4 (show MAP2K4 ELISA Kits) to JNK (show MAPK8 ELISA Kits) and the activation of p38 MAPK (show MAPK14 ELISA Kits).

  10. There are 2 isoforms: ROCK1 and ROCK2 (show ROCK2 ELISA Kits). They have different functions in different types of cells and tissues. There is growing evidence that ROCKs contribute to the development of cardiovascular diseases, including cardiac fibrosis, hypertrophy, and subsequent heart failure.

Rabbit rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) interaction partners

Pig (Porcine) rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) interaction partners

  1. Results indicate that ROCK1 and ROCK2 (show ROCK2 ELISA Kits) may exert different biological functions during the regulation of compaction and in ensuring development of porcine preimplantation embryos to the blastocyst stage.

  2. It is highly possible that Rho-kinase plays an important role in the pathogenesis of in-stent restenosis. Rho-kinase is not involved in endothelial regeneration after vascular injury.

Cow (Bovine) rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) interaction partners

  1. results suggest that the ROCK/MLC/actomyosin as well as ROCK/LIMK (show LIMK1 ELISA Kits)/cofilin (show CFL1 ELISA Kits) pathways regulate meiotic spindle migration and cytokinesis during bovine oocyte maturation.

  2. In airway smooth muscle, muscle contraction involves the translocation of ROCK1 from non-caveolar to caveolar regions.

  3. p38 (show MAPK14 ELISA Kits) phosphorylation and MMP13 (show MMP13 ELISA Kits) expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.

  4. The RhoA (show RHOA ELISA Kits)/ROCK signaling pathway is an important negative regulator of vascular calcification.

  5. caveolar and cholesterol integrity are indispensable for the proper functionality of the H(1) and 5-HT(2A (show HTR2A ELISA Kits)) receptors through their Rho/ROCK signaling.

  6. A functional contribution of PI3K, Rho, and ROCK to both the autocrine mechanism of ATP release and ATP-mediated angiogenic activation of vasa (show DDX4 ELISA Kits) vasorum endothelial cells, is reported.

ROCK1 Antigen Profile

Antigen Summary

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.

Alternative names and synonyms associated with ROCK1

  • Rho-associated, coiled-coil containing protein kinase 1 (ROCK1) Elisa Kit
  • Rho-associated, coiled-coil containing protein kinase 1 (LOC100229794) Elisa Kit
  • Rho-kinase (rok) Elisa Kit
  • Rho-associated coiled-coil containing protein kinase 1 (Rock1) Elisa Kit
  • Rho-associated, coiled-coil containing protein kinase 1 (rock1) Elisa Kit
  • 1110055K06Rik Elisa Kit
  • CG9774 Elisa Kit
  • Dmel\\CG9774 Elisa Kit
  • DRhk Elisa Kit
  • drok Elisa Kit
  • LOC100229794 Elisa Kit
  • p160ROCK Elisa Kit
  • Rhk Elisa Kit
  • RhoK Elisa Kit
  • Rock Elisa Kit
  • ROCK-1 Elisa Kit
  • ROCK-I Elisa Kit
  • ROCK1 Elisa Kit
  • Rok Elisa Kit
  • ROKalpha/beta Elisa Kit

Protein level used designations for ROCK1

Rho-associated coiled coil containing protein kinase 1 , rho-associated protein kinase 1 , Rho-associated, coiled-coil containing protein kinase 1 , CG9774-PA , DRho-kinase , ROCK , Rho-associated kinase , RhoA kinase , drosophila rho-associated kinase , rho kinase , rok-PA , Rho-associated coiled-coil forming kinase 1 , p160 ROCK-1 , p160ROCK , rho-associated, coiled-coil-containing protein kinase 1 , rho-associated, coiled-coil-containing protein kinase I , Rho-associated kinase beta , liver regeneration-related protein LRRG199 , p150 RhoA-binding kinase ROK beta , Rho kinase , p160-ROCK , renal carcinoma antigen NY-REN-35 , HEBM1 , cAMP-dependent protein kinase ROCK-I , cePKA , corneal epithelial Rho-associated-Ser/Thr kinase 1 , Rho-kinase beta , Rho-associated protein kinase 1 , rho-associated coiled-coil domain-containing protein kinase 1

100034056 Equus caballus
100229794 Taeniopygia guttata
43916 Drosophila melanogaster
19877 Mus musculus
81762 Rattus norvegicus
6093 Homo sapiens
480181 Canis lupus familiaris
100009220 Oryctolagus cuniculus
397447 Sus scrofa
785911 Bos taurus
455326 Pan troglodytes
100329779 Danio rerio
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