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anti-Mouse (Murine) ROCK2 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended ROCK2 Antibody (supplied by: Log in to see )

Antigen
rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) Antibodies
  • rocka-a
  • xROK
  • rock2
  • rok2
  • ROCK2
  • B230113H15Rik
  • ROKalpha
  • Rho-kinase
  • Rock-II
  • Rock2m
  • mKIAA0619
  • ROCK-II
  • ROK
  • Rho-associated, coiled-coil containing protein kinase 2
  • rho-associated, coiled-coil containing protein kinase 2a
  • Rho-associated coiled-coil containing protein kinase 2
  • Rho-associated coiled-coil containing protein kinase 2-like
  • rock2
  • rock2a
  • ROCK2
  • Rock2
  • LOC100346837
Reactivity
Human, Mouse (Murine), Rat (Rattus)
165
116
111
9
5
5
3
3
2
2
1
1
1
1
1
1
Host
Rabbit
144
21
1
Clonality
Polyclonal
Conjugate
This ROCK2 antibody is un-conjugated
5
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
121
43
39
38
31
25
25
11
3
3
2
Options
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Catalog No. ABIN673359
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN673364 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN673365 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN713069 IF (p) Cy3 Rabbit IgG pThr396 Log in to see Polyclonal
1 ABIN713071 IF (p) Cy5.5 Rabbit IgG pThr396 Log in to see Polyclonal
1 ABIN713072 IF (p) Cy7 Rabbit IgG pThr396 Log in to see Polyclonal
1 ABIN713073 IF (p) FITC Rabbit IgG pThr396 Log in to see Polyclonal
1 ABIN713085 IF (p) Cy5 Rabbit IgG pThr249 Log in to see Polyclonal
1 ABIN713086 IF (p) Cy5.5 Rabbit IgG pThr249 Log in to see Polyclonal
1 ABIN673362 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN673363 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN673366 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN713070 IF (p) Cy5 Rabbit IgG pThr396 Log in to see Polyclonal
1 ABIN713084 IF (p) Cy3 Rabbit IgG pThr249 Log in to see Polyclonal
1 ABIN713088 IF (p) FITC Rabbit IgG pThr249 Log in to see Polyclonal
1 ABIN713087 IF (p) Cy7 Rabbit IgG pThr249 Log in to see Polyclonal
1 ABIN877854 IF (p) Alexa Fluor 488 Rabbit IgG pThr249 Log in to see Polyclonal
1 ABIN877857 IF (p) Alexa Fluor 647 Rabbit IgG pThr249 Log in to see Polyclonal
1 ABIN877858 IF (p) Alexa Fluor 555 Rabbit IgG pThr249 Log in to see Polyclonal
1 ABIN877856 IF (p) Alexa Fluor 350 Rabbit IgG pThr249 Log in to see Polyclonal
1 ABIN878179 IF (p) Alexa Fluor 647 Rabbit IgG pThr396 Log in to see Polyclonal

Top referenced anti-ROCK2 antibody for Immunofluorescence (Paraffin-embedded Sections)

  • Human Polyclonal ROCK2 Primary Antibody for IF (p), IHC (p) - ABIN673359 (2 Publications): Wang, Zhang, Wang, Zhang, Mao, Zhuang, Tang, Luo, Zhou, Zhang: Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway. in The international journal of biochemistry & cell biology 2013 (PubMed)

Similar anti-ROCK2 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 21 Antibodies 21 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 3 Antibodies 3 Antibodies
Immunofluorescence (IF) 10 Antibodies 10 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 40 Antibodies 40 Antibodies
Immunohistochemistry (IHC) 17 Antibodies 17 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 28 Antibodies 28 Antibodies
Immunoprecipitation (IP) 13 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 67 Antibodies

General

Antigen rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(165), (116), (111), (9), (5), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(144), (21), (1)
Clonality
Polyclonal
Conjugate This ROCK2 antibody is un-conjugated
(5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(121), (43), (39), (38), (31), (25), (25), (11), (3), (3), (2)
Pubmed 2 references available
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Product Details anti-ROCK2 Antibody

Target Details ROCK2 Application Details Handling References for anti-ROCK2 Antibody (ABIN673359) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human ROCK2
Isotype IgG

Target Details ROCK2

Product Details anti-ROCK2 Antibody Application Details Handling References for anti-ROCK2 Antibody (ABIN673359) Images back to top
Antigen
Alternative Name Rock2 (ROCK2 Antibody Abstract)
Background

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP3, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p9RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.

Subcellular location: Cytoplasm


Synonyms: ROCK-II, Rho-associated protein kinase 2, Rho kinase 2, Rho-associated, coiled-coil-containing protein kinase 2, Rho-associated, coiled-coil-containing protein kinase II, p164 ROCK-2, ROCK2, KIAA619
Gene ID 9475
UniProt O75116
Research Area Cancer, Apoptosis/Necrosis
Pathways Microtubule Dynamics, WNT Signaling, Tube Formation

Application Details

Product Details anti-ROCK2 Antibody Target Details ROCK2 Handling References for anti-ROCK2 Antibody (ABIN673359) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-ROCK2 Antibody Target Details ROCK2 Application Details References for anti-ROCK2 Antibody (ABIN673359) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-ROCK2 Antibody (ABIN673359)

Product Details anti-ROCK2 Antibody Target Details ROCK2 Application Details Handling Images back to top
Product cited in:

He, Wei, Du, Meng, Zheng, Lai, Yao, Zhou, Wang, Luo, Ma, Zhang: "Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells." in: Cellular signalling, Vol. 31, pp. 87-95, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Wang, Zhang, Wang, Zhang, Mao, Zhuang, Tang, Luo, Zhou, Zhang: "Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 7, pp. 1447-56, 2013

Images

Product Details anti-ROCK2 Antibody Target Details ROCK2 Application Details Handling References for anti-ROCK2 Antibody (ABIN673359) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-ROCK2 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 2) (ABIN673359) Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti ROCK2 ...
Immunohistochemistry (IHC) image for anti-ROCK2 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 2) (ABIN673359) Formalin-fixed and paraffin embedded human gastric carcinoma tissue labeled with Anti...
SDS-PAGE (SDS) image for anti-ROCK2 antibody (rho-Associated, Coiled-Coil Containing Protein Kinase 2) (ABIN673359) Lane 1: rat brain lysates Lane 2: human colon carcinoma lysates probed with Anti ROCK...