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Browse our VPS4A Proteins (VPS4A)

Full name:
Vacuolar Protein Sorting 4 Homolog A (S. Cerevisiae) Proteins (VPS4A)
On www.antibodies-online.com are 3 Vacuolar Protein Sorting 4 Homolog A (S. Cerevisiae) (VPS4A) Proteins from 3 different suppliers available. Additionally we are shipping VPS4A Antibodies (33) and many more products for this protein. A total of 38 VPS4A products are currently listed.
Synonyms:
4930589C15Rik, AI325971, AW553189, SKD1, SKD1A, SKD2, VPS4, VPS4-1, vsp4, zgc:153907
list all proteins Gene Name GeneID UniProt
VPS4A 27183 Q9UN37
Rat VPS4A VPS4A 246772 Q793F9
Mouse VPS4A VPS4A 116733 Q8VEJ9

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VPS4A Proteins (VPS4A) by Origin

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More Proteins for VPS4A Interaction Partners

Human Vacuolar Protein Sorting 4 Homolog A (S. Cerevisiae) (VPS4A) interaction partners

  1. These results point to the existence of previously undetected biological functions of the FTase alpha (show FNTA Proteins) subunit (show POLG Proteins) that includes control of intracellular membrane trafficking.

  2. these experiments suggest that miR-16 (show GDE1 Proteins) and VPS4a expression are altered in end-stage heart failure and in response to unloading with a left ventricular assist device

  3. Ca2 (show CA2 Proteins)+-dependent accumulation of ESCRT III-Vps4 complex following large focal injury to the cell membrane and identify the role of ALG-2 (show PDCD6 Proteins) as the initiator of sequential ESCRT III-Vps4A/B complex assembly.

  4. Vps4A may function as a tumor suppressor, which utilizes exosomes as mediators to regulate the secretion and uptake of miRNAs in hepatoma cells; these observations provide new insights into the development of HCC (show FAM126A Proteins).

  5. Vps4 stimulatory element of the cofactor Vta1 (show VTA1 Proteins) contacts the ATPase Vps4 alpha7 and alpha9 subunits to stimulate ATP hydrolysis.

  6. Propose that the abscission checkpoint is mediated by ANCHR and CHMP4C (show CHMP4C Proteins) through retention of VPS4 at the midbody ring.

  7. VPS4 is required for endosomal transport of LDL cholesterol in HeLa cells.

  8. silencing CHMP6 (show CHMP6 Proteins) and VPS4A also blocked epidermal growth factor receptor (EGFR (show EGFR Proteins)) recycling

  9. VPS4, a master regulator of MVB sorting, may serve as a determinant of lysosomal targeting or extracellular secretion of alphaSYN and thereby contribute to the intercellular propagation of Lewy pathology in PD

  10. These results indicate that VPS4A has a direct role in membrane scission leading to HIV-1 release.

Mouse (Murine) Vacuolar Protein Sorting 4 Homolog A (S. Cerevisiae) (VPS4A) interaction partners

  1. A common substrate recognition mode conserved between katanin p60 (show STIP1 Proteins) and VPS4 governs microtubule severing and membrane skeleton reorganization

VPS4A Protein Profile

Protein Summary

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16\; the gene for the other resides on chromosome 18.

Alternative names and synonyms associated with VPS4A

  • vacuolar protein sorting 4 homolog A (S. cerevisiae) (VPS4A)
  • vacuolar sorting protein 4 (TP03_0351)
  • vacuolar protein sorting 4 homolog A (vps4a)
  • vacuolar protein sorting 4 homolog A (S. cerevisiae) (Vps4a)
  • vacuolar protein sorting 4a (yeast) (vps4a)
  • vacuolar protein sorting 4a (yeast) (Vps4a)
  • 4930589C15Rik protein
  • AI325971 protein
  • AW553189 protein
  • SKD1 protein
  • SKD1A protein
  • SKD2 protein
  • VPS4 protein
  • VPS4-1 protein
  • vsp4 protein
  • zgc:153907 protein

Protein level used designations for VPS4A

vacuolar protein sorting-associated protein 4A , vacuolar sorting protein 4 , vacuolar protein sorting 4 homolog A (S. cerevisiae) , SKD1-homolog , hVPS4 , vacuolar protein sorting factor 4A , vacuolar protein sorting 4a , vacuolar protein sorting protein 4a , vacuolar protein sorting 4 homolog A

GENE ID SPECIES
705277 Macaca mulatta
3500352 Theileria parva strain Muguga
100158600 Xenopus (Silurana) tropicalis
100600466 Nomascus leucogenys
447546 Xenopus laevis
27183 Homo sapiens
479674 Canis lupus familiaris
618168 Bos taurus
246772 Rattus norvegicus
100627841 Sus scrofa
767670 Danio rerio
116733 Mus musculus
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