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High eIF3i expression is associated with melanoma.
Clusterin (show CLU Proteins) is an independent predictive factor for prognosis of hepatocellular carcinoma and it facilitates metastasis through EIF3I/Akt (show AKT1 Proteins)/MMP13 (show MMP13 Proteins) signaling.
eIF3i is a proto-oncogene (show RAB1A Proteins) that drives colon oncogenesis by translationally upregulating COX-2 and activating the beta-catenin (show CTNNB1 Proteins) signaling pathway
POLR2J (show POLR2J Proteins) interacts with three different subunits of eIF3 (show EIF3A Proteins), eIF3a (show EIF6 Proteins), eIF3i, and eIF3m (show EIF3M Proteins).
findings report that short hairpin RNA mediated depletion of TRIP-1 (show PSMC5 Proteins) gene transcripts in A549 cells promotes epithelial-mesenchymal transition (EMT (show ITK Proteins)); knockdown of TRIP-1 (show PSMC5 Proteins) dramatically increased A549 responsiveness to TGF-beta1 (show TGFB1 Proteins) induction of EMT (show ITK Proteins)
eIF3i overexpression fosters the integration of growth signals by mTOR (show FRAP1 Proteins) into the mRNA translation process, promoting protein synthesis and tumor growth.
Subunit b of the eIF3 (show EIF3A Proteins) complex directly binds to HCV IRES domain III via its N-terminal-RRM.
TGF-beta receptor interacting protein 1 (TRIP-1), which we show inhibits fibroblast collagen contraction, is higher in fetal than adult fibroblasts
TRIP-1 is a regulator of osteoblast function
Mc1r (show MSHR Proteins)(e) mutation affects the proliferation and differentiation of melanocytes and l-Tyr (show TYR Proteins) rescues the reduced proliferative and differentiative activities by stimulating TYR (show TYR Proteins) activity and TRP1 (show TRPC1 Proteins) and TRP2 (show DCT Proteins) expressions as well as melanosome maturation
The translation initiation factor (show TIF1 Proteins) eIF3i up-regulates VEGF-A (show VEGFA Proteins), accelerates cell proliferation, and promotes angiogenesis in embryonic development.
may play a role in ATP-dependent RNA/DNA unwinding
, eukaryotic translation initiation factor 3 subunit 2 beta
, eukaryotic translation initiation factor 3 subunit I
, TGF-beta receptor-interacting protein 1
, TGFbeta receptor-interacting protein 1
, eIF3 p36
, eukaryotic translation initiation factor 3 subunit 2
, eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD)
, eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa
, predicted protein of HQ2242
, TGF-beta receptor binding protein
, eukaryotic translation initiation factor 3, subunit 1
, eukaryotic translation initiation factor 3, subunit 2 (beta)
, eukaryotic translation initiation factor 3, subunit 2 beta
, Eukaryotic translation initiation factor 3 subunit 2
, putative eukaryotic translation initiation factor 3 subunit 2 beta 36 kDa variant 1
, 26S protease regulatory subunit 8
, 26S proteasome AAA-ATPase subunit RPT6
, for proteasomal ATPase (SUG1)
, peptidase (prosome, macropain) 26S subunit, ATPase 5
, protease (prosome, macropain) 26S subunit, ATPase 5
, proteasomal ATPase (SUG1)
, proteasome 26S subunit ATPase 5
, proteasome p45/SUG
, proteasome subunit p45
, thyroid hormone receptor-interacting protein 1