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Human Polyclonal MAT1A Primary Antibody for ICC, IF - ABIN4332790
Yang, Cho, Li, Peng, Ko, Mato, Lu: MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma. in The Journal of clinical investigation 2013
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Human Polyclonal MAT1A Primary Antibody for IHC (p), WB - ABIN656632
Bing, Zhu, Yu, Li, Liu, Li, Wang, Qi, Guo, Yuan, He, Liu, Liu: Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells. in The Journal of biological chemistry 2014
Cow (Bovine) Polyclonal MAT1A Primary Antibody for WB - ABIN2776786
Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005
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interplay between MATalpha1, c-Myc (show MYC Antibodies), and Maf (show MAF Antibodies) proteins, and their deregulation during chronic cholestasis may facilitate cholangiocarcinoma oncogenesis
MAT1A is required for normal VLDL assembly and plasma lipid homeostasis in mice. Impaired VLDL synthesis, mainly due to SAMe deficiency, contributes to NAFLD (show TSC2 Antibodies) development in MAT1A-KO mice.
Deletion of the TFIIH kinase subunit Mat1 in mouse fibroblasts leads to dramatically reduced RNA polymerase II Ser5 phosphorylation.
DUSP1 (show DUSP1 Antibodies) mRNA and protein levels are lower in Mat1a knockout livers and fall rapidly in cultured hepatocytes.
investigated the function of the Cdk7 (show CDK7 Antibodies).cyclin (show PCNA Antibodies) H.Mat1 complex in murine embryonic stem (ES) cells and preimplantation embryos to determine whether it regulates the unique cell cycle structure and transcriptional network of pluripotent cells
This study demonstrates a requirement for MAT1 in the operation of PGC-1 (show PPARGC1A Antibodies) coactivators that control cell metabolism.
study found that Mat1 and Cdk7 (show CDK7 Antibodies) levels are undetectable in adipose tissues in vivo and downregulated during adipogenesis
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A
MAT1A knockout hepatocytes have more baseline DNA synthesis but no mitogenic response to hepatocyte growth factor (show HGF Antibodies). MAT1A-produced SAMe has a major role in ERK (show EPHB2 Antibodies) signaling & cyclin D1 (show CCND1 Antibodies) regulation during liver regeneration & mitogenic signal response.
Mat1a(-/-) mice have expansion of liver stem cells as they age. These cells have increased expression of several oncogenes and are tumorigenic in vivo.
PEA15 (show PEA15 Antibodies) expression was not significantly correlated with ovarian cancer antineoplastic drug resistance.
Of the 22 single nucleotide polymorphisms studied, the rs8193 polymorphism lying in the micro-RNA binding site of 3'-UTR (show UTS2R Antibodies) of CD44 (show CD44 Antibodies) was significantly (P=.0270) associated with RT-induced adverse skin reactions. Generalized multifactor dimensionality reduction analysis showed significant (P=.0107) gene-gene interactions between MAT1A and CD44 (show CD44 Antibodies).
A compound mutation of the methionine adenosyltransferase 1A (MAT1A) gene, c.345delA and c.529C>T, was identified in the patient, and His father and mother were found to be heterozygous for the c.345delA mutation and c.529C>T mutation, respectively.
S-adenosyl-L-methionine (show AS3MT Antibodies) diminishes hepatitis C virus expression by altering MAT1A/2A signaling in hepatocytes.
Data suggest the role of the phospholipase C epsilon (show PLCL1 Antibodies)-Protein kinase D (show PRKD1 Antibodies)-PEA15 (show PEA15 Antibodies) protein-ribosomal S6 kinase (show RPS6KB1 Antibodies)-IkappaB-NF-kappa B (show NFKB1 Antibodies) pathway in facilitating inflammation and inflammation-associated carcinogenesis in the colon.
Integrin alpha5beta1 and p53 (show TP53 Antibodies) convergent pathways in the control of anti-apoptotic proteins PEA-15 (show PEA15 Antibodies) and survivin (show BIRC5 Antibodies) in high-grade glioma.
High PED expression is associated with esophageal carcinoma.
The nuclear translocation of SApErk1/ 2 apart from PEA-15 (show PEA15 Antibodies) as an important mechanism to reverse senescence phenotype.
Latent HCMV infection of CD34 (show CD34 Antibodies) + cells protects cells from FAS (show FAS Antibodies)-mediated apoptosis through the cellular IL-10 (show IL10 Antibodies)/PEA-15 (show PEA15 Antibodies) pathway.
This gene encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake.
CDK-activating kinase assembly factor MAT1
, CDK7/cyclin H assembly factor
, CDK7/cyclin-H assembly factor
, RING finger protein MAT1
, S-adenosylmethionine synthase isoform type-1
, MAT 1
, S-adenosylmethionine synthetase isoform type-1
, adoMet synthase 1
, adoMet synthetase 1
, methionine adenosyltransferase 1
, methionine adenosyltransferase I/III
, S - adenosylmethionine synthetase
, 15 kDa phosphoprotein enriched in astrocytes
, Phosphoprotein enriched in astrocytes, 15kD
, astrocytic phosphoprotein PEA-15
, homolog of mouse MAT-1 oncogene
, phosphoprotein enriched in diabetes