Browse our MAX Proteins (MAX)

Full name:
MYC Associated Factor X Proteins (MAX)
On are 20 MYC Associated Factor X (MAX) Proteins from 9 different suppliers available. Additionally we are shipping MAX Antibodies (87) and MAX Kits (10) and many more products for this protein. A total of 132 MAX products are currently listed.
AA960152, AI875693, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, bHLHd9, CG9648, dmax, Dmel\\CG9648, fa92b04, fb52a04, fb95h11, max, wu:fa92b04, wu:fb52a04, wu:fb95h11, xmax, xmax2, xmax4, zmax
list all proteins Gene Name GeneID UniProt
MAX 17187  
MAX 4149 P61244
Rat MAX MAX 60661 P52164

Show all synonyms

MAX Proteins (MAX) by Origin

Select your origin of interest

Top referenced MAX Proteins

  1. Human MAX Protein expressed in Escherichia coli (E. coli) - ABIN666983 : Burbano, Hodges, Green, Briggs, Krause, Meyer, Good, Maricic, Johnson, Xuan, Rooks, Bhattacharjee, Brizuela, Albert, de la Rasilla, Fortea, Rosas, Lachmann, Hannon, Pääbo: Targeted investigation of the Neandertal genome by array-based sequence capture. in Science (New York, N.Y.) 2010 (PubMed)

  2. Human MAX Protein expressed in Baculovirus infected Insect Cells - ABIN2005345 : Mac Partlin, Homer, Robinson, McCormick, Crouch, Durant, Matheson, Hall, Gillespie, Brown: Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX. in Oncogene 2003 (PubMed)

More Proteins for MAX Interaction Partners

Fruit Fly (Drosophila melanogaster) MYC Associated Factor X (MAX) interaction partners

  1. We find that many biological activities of Myc (show MYC Proteins) do not, or only partly, require the association with Max--

Mouse (Murine) MYC Associated Factor X (MAX) interaction partners

  1. Studies suggest that inducible MYC Associated Factor X (MAX) knockout embryonic stem cells (ESCs (show NR2E3 Proteins)) provide an excellent platform for exploring the molecular mechanisms of meiosis initiation.

  2. Myc (show MYC Proteins) represses C/EBPdelta (show CEBPD Proteins) expression by associating with the C/EBPdelta (show CEBPD Proteins) proximal promoter as a transient component of a repressive complex that includes Max and Miz1 (show PIAS2 Proteins)

  3. The switch from Mnt-Max to Myc (show MYC Proteins)-Max during bile duct ligation (cholestasis) and in hepatocytes treated with lithocholic acid is responsible for the induction in p53 (show TP53 Proteins) and cyclin D1 (show CCND1 Proteins) expression and contributes to apoptosis.

  4. the c-Myc (show MYC Proteins)-Max complex exerts its transcriptional regulatory role and hnRNP U (show HNRNPU Proteins) may be a coactivator of this transcriptional activator complex.

Human MYC Associated Factor X (MAX) interaction partners

  1. These results suggest that the wild type Max homodimer is important for attenuating the binding of c-Myc (show MYC Proteins) to specific and non-specific DNA, whereas alternative splicing (e.g. DeltaMax) is unable to do so. Conversely, the splicing of Max into DeltaMax could provoke an increase in overall chromatin bound c-Myc (show MYC Proteins).

  2. The mechanism of inhibition of c-Myc (show MYC Proteins) transcriptional activity by Miz-1 (show ZBTB17 Proteins) that binds c-Myc (show MYC Proteins) while competing for binding with Max has been described.

  3. The introduction of wild-type MAX cDNA into PC12 cells significantly decreased MYC's ability to bind to canonical E-boxes, while pathogenic MAX proteins were not able to fully repress MYC (show MYC Proteins) activity. Further clinical and molecular evaluation of variant carriers corroborated the results obtained with the functional assessment.

  4. Celastrol and some of its quinone methidecontaining analogs directly inhibit c-Myc (show MYC Proteins)-Max heterodimers in tumor cells.

  5. We confirmed that these dimeric inhibitors directly bind to Myc (show MYC Proteins) blocking its interaction with Max and affect transcription of MYC (show MYC Proteins) dependent genes.

  6. MYC (show MYC Proteins) is part of a network of bHLHLZ proteins centered on the MYC (show MYC Proteins) heterodimeric partner MAX and its counterpart, the MAX-like protein MLX (show MLX Proteins).

  7. Myc (show MYC Proteins) and its obligate heterodimeric partner, Max, are integral to the coordinated recruitment and post-translational modification of components of the core transcriptional machinery.

  8. Here we review the activities of MYC (show MYC Proteins), MNT (show MNT Proteins) and other MAX interacting proteins in the setting of T and B cell activation (show BLNK Proteins) and oncogenesis

  9. Delta Max, but not full-length Max, rescues Myc (show MYC Proteins)-dependent glycolytic gene expression upon induced EGFRvIII loss, and correlates with hnRNPA1 (show HNRNPA1 Proteins) expression and downstream Myc (show MYC Proteins)-dependent gene transcription in patients.

  10. Data show that Sirt1 (show SIRT1 Proteins), p53 (show TP53 Proteins), and p38(MAPK (show MAPK14 Proteins)) are involved in the detrimental phenotype of Max-null ESCs (show NR2E3 Proteins). Analyses revealed these proteins are involved at varying levels to one another in the hierarchy of the pathway leading to cell death in Max-null ESCs (show NR2E3 Proteins).

MAX Protein Profile

Protein Summary

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with MAX

  • CG9648 gene product from transcript CG9648-RA (Max)
  • MYC associated factor X (max-a)
  • MYC associated factor X (MAX)
  • MYC associated factor X (max)
  • Max protein (Max)
  • MYC associated factor X (max-b)
  • MYC associated factor X (Max)
  • myc-associated factor X (max)
  • AA960152 protein
  • AI875693 protein
  • bHLHd4 protein
  • bHLHd5 protein
  • bHLHd6 protein
  • bHLHd7 protein
  • bHLHd8 protein
  • bHLHd9 protein
  • CG9648 protein
  • dmax protein
  • Dmel\\CG9648 protein
  • fa92b04 protein
  • fb52a04 protein
  • fb95h11 protein
  • max protein
  • wu:fa92b04 protein
  • wu:fb52a04 protein
  • wu:fb95h11 protein
  • xmax protein
  • xmax2 protein
  • xmax4 protein
  • zmax protein

Protein level used designations for MYC Associated Factor X Proteins (MAX)

CG9648-PA , CG9648-PC , Max-PA , Max-PC , Max homologue 2 , Myc binding protein Xmax4 , myc-associated factor X , protein max , xMAX , MYC associated factor X , myc-binding novel HLH/LZ protein , protein myn , class D basic helix-loop-helix protein 4 , Myc binding protein Xmax2

40095 Drosophila melanogaster
373652 Xenopus laevis
452972 Pan troglodytes
493570 Xenopus (Silurana) tropicalis
100215471 Hydra magnipapillata
17187 Mus musculus
4149 Homo sapiens
504192 Xenopus laevis
100858676 Gallus gallus
609969 Canis lupus familiaris
540616 Bos taurus
60661 Rattus norvegicus
493947 Felis catus
30467 Danio rerio
Selected quality suppliers for MAX Proteins (MAX)
Did you look for something else?