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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion.
39S ribosomal protein L28, mitochondrial
, melanoma antigen p15
, melanoma-associated antigen recognised by cytotoxic T lymphocytes
, melanoma-associated antigen recognized by T lymphocytes
, melanoma-associated antigen recognized by T-lymphocytes
, cyclin-dependent kinase 4 inhibitor B
, Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4)
, ecdysteroid regulated 16kd protein
, melanoma antigen P15
, mitochondrial ribosomal protein L28
, mitochondrial ribosomal protein subunit L28
, likely mitochondrial ribosomal protein MRPL28p
, Putative mitochondrial ribosomal protein L28