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Browse our ORC6 (ORC6) ELISA Kits

Full name:
Origin Recognition Complex, Subunit 6 ELISA Kits (ORC6)
On www.antibodies-online.com are 0 Origin Recognition Complex, Subunit 6 (ORC6) ELISA Kits from different suppliers available. Additionally we are shipping ORC6 Antibodies (55) and ORC6 Proteins (8) and many more products for this protein. A total of 73 ORC6 products are currently listed.
Synonyms:
6720420I10Rik, ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6, ATORC6, CG1584, DDBDRAFT_0186183, DDBDRAFT_0233113, DDB_0186183, DDB_0233113, Dmel\\CG1584, DmORC6, DmORC 6, LOC100284755, ORC, orc6, orc6l, origin recognition complex protein 6, ORIGIN RECOGNITION COMPLEX SUBUNIT 6, rDmORC, T2P11.3, T2P11_3
list all ELISA KIts Gene Name GeneID UniProt
Rat ORC6 ORC6 291927  
Human ORC6 ORC6 23594 Q9Y5N6
Mouse ORC6 ORC6 56452  

Show all synonyms

More ELISA Kits for ORC6 Interaction Partners

Fruit Fly (Drosophila melanogaster) Origin Recognition Complex, Subunit 6 (ORC6) interaction partners

  1. In order to study the effects of Meier-Gorlin syndrome (MGS (show GYS1 ELISA Kits)) mutation in an animal model system, MGS (show GYS1 ELISA Kits) mutation in Orc6 was introduced and established Drosophila model of MGS (show GYS1 ELISA Kits).

  2. Drosophila Orc6 protein, the smallest subunit of the origin recognition complex (ORC), directly binds to septin complex and facilitates septin filament formation.

  3. Drosophila ORC6 protein cytokinetic function resides in a domain distinct from its replication activity

  4. These studies provide a molecular analysis for the functional requirement of Orc6 in replicative functions of ORC in Drosophila and suggest that Orc6 may contribute to the sequence preferences of ORC in targeting to the origins.

  5. These results show that the interaction of Orc6 with the septin (show SEPT1 ELISA Kits) complex is dependent on the coiled-coil domain of Pnut, and suggest an active role for Orc6 in septin (show SEPT1 ELISA Kits) complex function.

  6. In a cross-species complementation experiment, the expression of human Orc6 in Drosophila Orc6 mutant cells rescued DNA replication, suggesting that this function of the protein is conserved among metazoans.

Human Origin Recognition Complex, Subunit 6 (ORC6) interaction partners

  1. The present report expands the clinical phenotype associated with ORC6 mutations to include severely abnormal embryological development suggesting a possible genotype-phenotype correlation.

  2. our results suggest that Meier-Gorlin syndrome mutations in Orc6 impair the formation of ORC hexamers, interfering with appropriate ORC functions

  3. findings show that Orc6 not only interacts with Orc1 (show ORC1L ELISA Kits)-Orc5 but also with the initiation factor Cdc6 (show CDC6 ELISA Kits), and that Orc6 functions at different stages of the replication initiation process.

  4. Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB (show GTF2B ELISA Kits).

  5. results implicate Orc6 as an essential gene that coordinates chromosome replication and segregation with cytokinesis

  6. Study using HCT116 haplo-insufficient (show TGFb ELISA Kits) cells and Orc2 hypomorphic cells demonstrates that the binding of human Ku to replication origins precedes that of Orc-3 (show ORC3 ELISA Kits), -4, and -6 subunit binding.

  7. Orc6 has a role in sensitizing human colon cancer cells to 5-fluorouracil and cisplatin

  8. In a cross-species complementation experiment, the expression of human Orc6 in Drosophila Orc6 mutant cells rescued DNA replication, suggesting that this function of the protein is conserved among metazoans.

Mouse (Murine) Origin Recognition Complex, Subunit 6 (ORC6) interaction partners

  1. Study reports that ORC6L is another component required for acquisition of DNA replication competence that is absent in mouse oocytes.

ORC6 Antigen Profile

Antigen Summary

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Alternative names and synonyms associated with ORC6

  • origin recognition complex, subunit 6 (Orc6) Elisa Kit
  • Origin recognition complex subunit 6 (Orc6) Elisa Kit
  • origin recognition complex, subunit 6 (ORC6) Elisa Kit
  • origin recognition complex subunit 6 (ORC6) Elisa Kit
  • origin recognition complex subunit 6 (CpipJ_CPIJ005016) Elisa Kit
  • origin recognition complex subunit 6 (SJAG_01267) Elisa Kit
  • origin recognition complex subunit 6 (orcF) Elisa Kit
  • origin recognition complex subunit 6 (LOC100284755) Elisa Kit
  • origin recognition complex, subunit 6 (orc6) Elisa Kit
  • 6720420I10Rik Elisa Kit
  • ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 Elisa Kit
  • ATORC6 Elisa Kit
  • CG1584 Elisa Kit
  • DDBDRAFT_0186183 Elisa Kit
  • DDBDRAFT_0233113 Elisa Kit
  • DDB_0186183 Elisa Kit
  • DDB_0233113 Elisa Kit
  • Dmel\\CG1584 Elisa Kit
  • DmORC6 Elisa Kit
  • DmORC 6 Elisa Kit
  • LOC100284755 Elisa Kit
  • ORC Elisa Kit
  • orc6 Elisa Kit
  • orc6l Elisa Kit
  • origin recognition complex protein 6 Elisa Kit
  • ORIGIN RECOGNITION COMPLEX SUBUNIT 6 Elisa Kit
  • rDmORC Elisa Kit
  • T2P11.3 Elisa Kit
  • T2P11_3 Elisa Kit

Protein level used designations for ORC6

origin recognition complex subunit 6 , origin recognition complex, subunit 6-like , CG1584-PA , Orc6-PA , origin recognition complex, subunit 6 like

GENE ID SPECIES
291927 Rattus norvegicus
36017 Drosophila melanogaster
415749 Gallus gallus
465140 Pan troglodytes
839227 Arabidopsis thaliana
6036630 Culex quinquefasciatus
7048414 Schizosaccharomyces japonicus yFS275
8624765 Dictyostelium discoideum AX4
100284755 Zea mays
549939 Xenopus (Silurana) tropicalis
23594 Homo sapiens
482492 Canis lupus familiaris
515476 Bos taurus
56452 Mus musculus
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