Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T (show USP5 ELISA Kits) in fetal Down syndrome.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.
, proteasome alpha subunit
, proteasome alpha5 subunit
, proteasome subunit alpha type 5
, hypothetical protein
, macropain zeta chain
, multicatalytic endopeptidase complex zeta chain
, proteasome subunit alpha type-5
, proteasome zeta chain
, proteasome alpha 5 subunit
, macropain subunit zeta
, proteasome component 5
, proteasome subunit zeta
, proteasome subunit, alpha type, 5