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Browse our anti-PSMB10 (PSMB10) Antibodies

Full name:
anti-Proteasome (Prosome, Macropain) Subunit, beta Type 10 Antibodies (PSMB10)
On www.antibodies-online.com are 63 Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10) Antibodies from 15 different suppliers available. Additionally we are shipping PSMB10 Proteins (7) and many more products for this protein. A total of 74 PSMB10 products are currently listed.
Synonyms:
beta2i, LMP10, Mecl-1, MECL1
list all antibodies Gene Name GeneID UniProt
PSMB10 19171 O35955
PSMB10 291983 Q4KM35
PSMB10 5699 P40306

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Most Popular Reactivities for anti-PSMB10 (PSMB10) Antibodies

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anti-Mouse (Murine) PSMB10 Antibodies:

anti-Rat (Rattus) PSMB10 Antibodies:

anti-Human PSMB10 Antibodies:

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Top referenced anti-PSMB10 Antibodies

  1. Human Monoclonal PSMB10 Primary Antibody for IF, ELISA - ABIN519388 : Nijholt, de Graaf, van Haastert, Oliveira, Berkers, Zwart, Ovaa, Baas, Hoozemans, Scheper: Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease. in Cell death and differentiation 2011 (PubMed)

  2. Cow (Bovine) Polyclonal PSMB10 Primary Antibody for WB - ABIN2786722 : Liu, Li, Qiu, Guo, Li, Zhang: Molecular characterization, expression and mapping of porcine LMP2 and MECL-1 genes. in DNA sequence : the journal of DNA sequencing and mapping 2007 (PubMed)

  3. Human Polyclonal PSMB10 Primary Antibody for ELISA, IHC - ABIN4348255 : Moschonas, Kouraki, Knox, Thymiakou, Kardassis, Eliopoulos: CD40 induces antigen transporter and immunoproteasome gene expression in carcinomas via the coordinated action of NF-kappaB and of NF-kappaB-mediated de novo synthesis of IRF-1. in Molecular and cellular biology 2008 (PubMed)

More Antibodies against PSMB10 Interaction Partners

Mouse (Murine) Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10) interaction partners

  1. LMP7 (show PSMB8 Antibodies) and MECL1 regulate cytokine expression, suggesting this system represents a novel mechanism for the regulation of cytokines and cytokine signaling

  2. Findings strongly support the concept that LMP7 (show PSMB8 Antibodies)/MECL-1 proteasomes subunits actively function to regulate LPS (show TLR4 Antibodies)-induced NO production by affecting the TRIF/TRAM (show TICAM2 Antibodies) pathway.

  3. phenotype of hyperproliferation of T cells lacking both MECL-1 and LMP7 implicates a specific role for immunoproteasomes in T cell proliferation that is not obviously connected to MHC class I Ag processing

  4. An in vivo function of MECL-1 codetermines the T cell repertoire for an antiviral cytotoxic T lymphocyte (CTL) response specific for lymphocytic choriomeningitis virus that is altered in MECL1-deficient mice.

  5. The findings indicate that MECL-1 influences the homeostatic equilibrium between T-cell subsets, not through indirect extracellular signals, such as MHC-I expression or the cytokine milieu, but through direct effects on T-cell-intrinsic processes.

Human Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10) interaction partners

  1. designed siRNAs that efficiently silence LMP2 (show PSMB9 Antibodies), LMP7 (show PSMB8 Antibodies) and MECL-1 gene expression.

  2. LMP10 nuclear expression in the Human Papillomavirus (HPV)-positive group and LMP10 cytoplasmic expression in the HPV-negative group of patients correlated to better clinical outcome.

  3. Data indicate that treatment-emergent resistance to single-agent bortezomib was independent of variants in the proteasome genes PSMB1 (show PSMB1 Antibodies), PSMB5 (show PSMB5 Antibodies), PSMB6 (show PSMB6 Antibodies), PSMB8 (show PSMB8 Antibodies), PSMB9 (show PSMB9 Antibodies), and PSMB10.

  4. Adenovirus E1A (show BCKDHA Antibodies) causes down-regulation of MECL1 expression

  5. Impaired expression of proteasome subunits is involved in the loss of HLA class I (show MICA Antibodies) expression in human colon cancer cells.

  6. Multicatalytic endopeptidase complex subunit is involved in antigen presentation and is an important candidate gene for initial exploration of relationships between antigen processing genes and disease resistance.

  7. These data reveal a novel "feed-forward" mechanism induced by NF-kappaB (show NFKB1 Antibodies) which ensures that acutely synthesized IRF-1 (show IRF1 Antibodies) operates in concert with NF-kappaB (show NFKB1 Antibodies) to amplify the immunoproteasome and antigen-processing functions of CD40 (show CD40 Antibodies).

Pig (Porcine) Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10) interaction partners

  1. The porcine PSMB10 was mapped by somatic cell hybrid panel and radiation hybrid mapping on SSC6p14-p15 (show CDKN2B Antibodies).

PSMB10 Antigen Profile

Antigen Summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.

Alternative names and synonyms associated with PSMB10

  • proteasome (prosome, macropain) subunit, beta type 10 (Psmb10) antibody
  • proteasome (prosome, macropain) subunit, beta type, 10 (PSMB10) antibody
  • beta2i antibody
  • LMP10 antibody
  • Mecl-1 antibody
  • MECL1 antibody

Protein level used designations for PSMB10

low molecular mass protein 10 , macropain subunit MECl-1 , multicatalytic endopeptidase complex subunit MECl-1 , prosome Mecl1 , proteasome (prosomome, macropain) subunit, beta type 10 , proteasome MECl-1 , proteasome subunit MECL1 , proteasome subunit beta type-10 , proteasome subunit beta-2i , proteasome catalytic subunit 2i , proteasome subunit beta 7i , proteasome beta 10 subunit

GENE ID SPECIES
19171 Mus musculus
291983 Rattus norvegicus
5699 Homo sapiens
489749 Canis lupus familiaris
733626 Sus scrofa
282328 Bos taurus
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