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Browse our Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 Proteins (PSMC4)

Full name:
Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 Proteins (PSMC4)
On www.antibodies-online.com are 9 Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4) Proteins from 6 different suppliers available. Additionally we are shipping Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 Antibodies (41) and Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 Kits (1) and many more products for this protein. A total of 56 Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 products are currently listed.
Synonyms:
AO090003000692, CIP21, DDBDRAFT_0188209, DDBDRAFT_0191435, DDB_0188209, DDB_0191435, MIP224, NCU02260.1, RPT3, S6, TBP-7, Tbp7
list all proteins Gene Name GeneID UniProt
PSMC4 5704 P43686
PSMC4 23996 P54775
Rat PSMC4 PSMC4 117262 Q63570

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Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 Proteins (PSMC4) by Origin

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More Proteins for Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 Interaction Partners

Human Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4) interaction partners

  1. Site-specific Rpt3 phosphorylation by DYRK2 (show DYRK2 Proteins) controls cell proliferation and tumorigenesis in breast neoplasms.

  2. The proposed TRAP1 (show TRAP1 Proteins) network has an impact in vivo, as it is conserved in human colorectal cancers, is controlled by ER-localized TRAP1 (show TRAP1 Proteins) interacting with TBP7 and provides a novel model of the ER-mitochondria crosstalk.

  3. C terminus of Rpt3, an ATPase subunit of PA700 (19 S) regulatory complex, is essential for 26 S proteasome assembly but not for activation

  4. interacts with gankyrin (show PSMD10 Proteins) through C-terminal 78 amino acids

  5. a novel specific interaction of synphilin-1 (show SNCAIP Proteins) with the regulatory proteasomal protein S6 ATPase (tbp7) in aggresome-like intracytoplasmic inclusions

  6. An insertion/deletion variant in intron 5 of the S6 ATPase gene was more frequent in German Parkinson's disease patients compared to controls

Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4) Protein Profile

Protein Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4)

  • 26S protease regulatory subunit 6B (LOC732870)
  • 26S protease regulatory subunit 6B (NCU02260)
  • 26S protease regulatory subunit 6B (ATEG_04674)
  • 26S protease regulatory subunit 6B (LELG_01296)
  • 26S protease regulatory subunit 6B (HCAG_00039)
  • 26S protease regulatory subunit 6b (AaeL_AAEL007297)
  • 26S protease regulatory subunit 6B (GL50803_7950)
  • 26S protease regulatory subunit 6B (EDI_044950)
  • 26S protease regulatory subunit 6B (AOR_1_1218154)
  • 26S protease regulatory subunit 6B (PTRG_03339)
  • 26S protease regulatory subunit 6B (psmC4)
  • 26S protease regulatory subunit 6B (prs6b)
  • 26S protease regulatory subunit 6B (LOC100381342)
  • 26S protease regulatory subunit 6b (prs6b)
  • proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4)
  • proteasome (prosome, macropain) 26S subunit, ATPase, 4 (Psmc4)
  • AO090003000692 protein
  • CIP21 protein
  • DDBDRAFT_0188209 protein
  • DDBDRAFT_0191435 protein
  • DDB_0188209 protein
  • DDB_0191435 protein
  • MIP224 protein
  • NCU02260.1 protein
  • RPT3 protein
  • S6 protein
  • TBP-7 protein
  • Tbp7 protein

Protein level used designations for PSMC4

26S protease regulatory subunit 6B , 26S protease regulatory subunit 6b , 26S proteasome subunit ATPase 4 , HIV TAT binding-protein-related , 26S proteasome regulatory complex ATPase RPT3 , GRMZM2G090904 , 26S proteasome AAA-ATPase subunit RPT3 , MB67-interacting protein , Tat-binding protein 7 , protease 26S subunit 6 , CAR interacing protein 21 , CAR interacting protein 21 , TAT-binding protein 7 , TBP-7 , proteasome 26S ATPase subunit 4 , proteasome 26S subunit ATPase 4 , S6 ATPase

GENE ID SPECIES
732870 Bombyx mori
3876090 Neurospora crassa OR74A
4320472 Aspergillus terreus NIH2624
5235048 Lodderomyces elongisporus NRRL YB-4239
5451414 Ajellomyces capsulatus NAm1
5568998 Aedes aegypti
5703143 Giardia lamblia ATCC 50803
5882902 Entamoeba dispar SAW760
5991824 Aspergillus oryzae RIB40
6341569 Pyrenophora tritici-repentis Pt-1C-BFP
8626913 Dictyostelium discoideum AX4
100286726 Salmo salar
100381342 Zea mays
100528979 Ictalurus punctatus
5704 Homo sapiens
23996 Mus musculus
117262 Rattus norvegicus
510029 Bos taurus
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