Browse our Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) ELISA Kits

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Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 ELISA Kits (PSMD10)
On www.antibodies-online.com are 17 Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) ELISA Kits from 5 different suppliers available. Additionally we are shipping Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 Antibodies (97) and Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 Proteins (18) and many more products for this protein. A total of 141 Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 products are currently listed.
Synonyms:
AW554874, dJ889N15.2, gankyrin, p28, p28(GANK), p28Gank, zgc:109707
list all ELISA KIts Gene Name GeneID UniProt
PSMD10 5716 O75832
PSMD10 53380 Q9Z2X2
PSMD10 116722 Q9Z2X3

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More ELISA Kits for Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 Interaction Partners

Zebrafish Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) interaction partners

  1. Gankyrin expression promotes spontaneous cancer and non-cancerous liver diseases. Gankyrin accelerates liver steatosis, cholangitis, fibrosis, and hepatocarcinogenesis with persistent damage and proliferation in hepatocytes.

  2. This study is the first to report gankyrin as a potential link between microRNAs and liver steatosis in zebrafish.

Human Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) interaction partners

  1. The positive feedback regulation involving gankyrin and Nrf2 (show GABPA ELISA Kits) modulates a series of antioxidant enzymes, thereby lowering intracellular ROS (show ROS1 ELISA Kits) and conferring a steadier intracellular environment, which prevents mitochondrial damage and cell death induced by excessive oxidative stress.

  2. Gankyrin enhanced gastric cancer cell proliferation by regulating cell cycle-related proteins and by activating PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) signaling pathway. Gankyrin played an important role in gastric carcinogenesis and could be a potential effective therapeutic target for enhancing chemosensitivity to 5-fluorouracil and cisplatin.

  3. gankyrin is an oncoprotein that can be modified by small molecules in tumor cell lines

  4. Gankyrin overexpression activates mTORC1 signaling and accelerating TSC2 (show TSC2 ELISA Kits) degradation in colorectal tumor cells.

  5. Gankyrin is an oncoprotein that facilitates the degradation of two key tumor suppressors, namely, Rb and p53 (show TP53 ELISA Kits). Gankyrin is involved in the regulation of cell signaling pathways, with particular reference to RhoA (show RHOA ELISA Kits)/ROCK/PTEN/PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits), beta-catenin (show CTNNB1 ELISA Kits), IL-6 (show IL6 ELISA Kits)/STAT3 (show STAT3 ELISA Kits), and IL-1beta (show IL1B ELISA Kits)/IRAK-1 (show IRAK1 ELISA Kits) inflammatory signaling. Review.

  6. Gankyrin-overexpressed non-small cell lung cancer patients had a significantly shorter survival time

  7. Results identified rs111638916 SNP in the PSMD10 3'-UTR (show UTS2R ELISA Kits) as a risk factor for gastric cancer (GC) and acted as a tumor promoting factor. SNP rs111638916 was also regulated by miR (show MLXIP ELISA Kits)-505, resulting in its up-regulation in patients with GA and AA genotypes.

  8. p28GANK expression was increased in metastatic ESCC tissues and cells, and p28GANK knockdown decreased the metastatic ability of ESCC cells.

  9. This study identifies gankyrin, for the first time, as new potential predictive and oncogenic factor of well-differentiated/dedifferentiated liposarcoma, suggesting the potential for service as a future Liposarcoma therapeutic approach.

  10. On the base results of present study one can suggests the p28GANK being useful as a predictive marker for patient prognosis and a novel therapeutic target for gastric cancer.

Mouse (Murine) Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) interaction partners

  1. the present study clarified, at least partly, mechanisms of vascular tumorigenesis, and suggests that gankyrin might play a physiological role in hypoxic responses besides its roles as an oncoprotein.

  2. FXR (show NR1H4 ELISA Kits) prevents liver cancer by inhibiting the gankyrin promoter via C/EBPbeta (show CEBPB ELISA Kits)-HDAC1 (show HDAC1 ELISA Kits) complexes, leading to subsequent protection of tumor suppressor proteins from degradation.

  3. Gankyrin is a key regulator of Ras-mediated activation of Akt through inhibition of the downstream RhoA/ROCK pathway and thus plays an essential role in Ras-induced tumorigenesis.

  4. Findings suggest that retinoblastoma protein degradation in Lmna (show LMNA ELISA Kits)-/- cells occurs by gankyrin and MDM2 (show MDM2 ELISA Kits)-independent mechanisms.

  5. Gankyrin oncoprotein has a role in progression of esophageal squamous cell carcinoma

Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) Antigen Profile

Antigen Summary

This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.

Alternative names and synonyms associated with Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10)

  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (psmd10) Elisa Kit
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (PSMD10) Elisa Kit
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (Psmd10) Elisa Kit
  • AW554874 Elisa Kit
  • dJ889N15.2 Elisa Kit
  • gankyrin Elisa Kit
  • p28 Elisa Kit
  • p28(GANK) Elisa Kit
  • p28Gank Elisa Kit
  • zgc:109707 Elisa Kit

Protein level used designations for PSMD10

26S proteasome non-ATPase regulatory subunit 10 , gank , proteasome 26S subunit, non-ATPase, 10 , 26S proteasome regulatory subunit p28 , ankyrin repeat protein , gankyrin , hepatocellular carcinoma-associated protein p28-II , proteasome subunit p28 , proteosome (prosome, macropain) 26S subunit, non-ATPase, 10 , proteosome subunit p28 , proteasome 26S non-ATPase subunit 10

GENE ID SPECIES
403085 Danio rerio
5716 Homo sapiens
53380 Mus musculus
116722 Rattus norvegicus
481014 Canis lupus familiaris
535414 Bos taurus
100724287 Cavia porcellus
101113657 Ovis aries
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