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Browse our anti-PSME3 (PSME3) Antibodies

Full name:
anti-PSME3 Antibodies (PSME3)
On www.antibodies-online.com are 60 PSME3 Antibodies from 16 different suppliers available. Additionally we are shipping PSME3 Proteins (14) and PSME3 Kits (8) and many more products for this protein. A total of 88 PSME3 products are currently listed.
Synonyms:
AA410043, Ab2-371, AU020960, Ki, PA28-gamma, PA28G, PA28gamma, psme3b, REG-GAMMA, REGgamma
list all antibodies Gene Name GeneID UniProt
PSME3 19192 P61290
PSME3 287716  
PSME3 10197 P61289

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Most Popular Reactivities for anti-PSME3 (PSME3) Antibodies

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anti-Mouse (Murine) PSME3 Antibodies:

anti-Rat (Rattus) PSME3 Antibodies:

anti-Human PSME3 Antibodies:

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Top referenced anti-PSME3 Antibodies

  1. Chicken Polyclonal PSME3 Primary Antibody for WB - ABIN2782512 : Pratt, Rechsteiner: Proteasomes cleave at multiple sites within polyglutamine tracts: activation by PA28gamma(K188E). in The Journal of biological chemistry 2008 (PubMed)

  2. Dog (Canine) Monoclonal PSME3 Primary Antibody for BI, WB - ABIN968402 : Kohda, Ishibashi, Shimbara, Tanaka, Matsuda, Kasahara et al.: Characterization of the mouse PA28 activator complex gene family: complete organizations of the three member genes and a physical map of the approximately 150-kb region containing the alpha- and ... in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)

More Antibodies against PSME3 Interaction Partners

Mouse (Murine) PSME3 interaction partners

  1. Study demonstrated that Psme3/Psme4 (show PSME4 Antibodies) double KO (dKO) male mice are completely infertile and showed the up-regulation of several proteins involved in oxidative stress response in dKO sperms. These results suggest the important role of PA28gamma and PA200 (show PSME4 Antibodies) in male fertility.

  2. Findings reveal a novel regulatory pathway in which the REGgamma-proteasome controls the steady-state level of GSK3beta (show GSK3b Antibodies) protein.

  3. PSME3 is a target gene of NF-kappaB (show NFKB1 Antibodies) during bacterial infections. PSME3 activates NF-kappaB (show NFKB1 Antibodies) by degrading KLF2 (show KLF2 Antibodies).

  4. REGgamma-mediated control of IkappaBvarepsilon contributes to NFkappaB activation and promotes bowel inflammation and associated tumour formation in response to chronic injury

  5. REGgamma acts in skin tumorigenesis mediating MAPK/p38 (show MAPK1 Antibodies) activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  6. In a p53 (show TP53 Antibodies)-dominated cellular context, pro-apoptotic signaling might be overcome by PA28gamma-mediated caspase (show CASP3 Antibodies) inhibition.

  7. Data suggest levels of gene expression of both Psme3 (proteasome activator subunit 3) and Dusp3 (dual specificity phosphatase 3 (show DUSP3 Antibodies)) are associated with susceptibility to Staphylococcus aureus infection/sepsis in humans and in mouse disease model.

  8. PKA turnover by the REGgamma-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis.

  9. REGgamma binds to SirT1 (show SIRT1 Antibodies), promotes its Ub-independent degradation, and inhibits its activity to deacetylate autophagy-related proteins, thereby inhibiting autophagy under normal conditions.

  10. REGgamma-deficient mice develop premature aging phenotypes that are associated with abnormal accumulation of casein kinase (CK)1delta and p53 (show TP53 Antibodies). Antibody array analysis identified CK1delta as a direct target of REGgamma.

Human PSME3 interaction partners

  1. Study demonstrated that the gene therapy with proteasome activator, PA28gamma can improve ubiquitin-proteasome system function as well as behavioral abnormalities in Huntington's disease model mice

  2. Surrogate Prognostic Biomarkers in OSCC: The Paradigm of PA28gamma Overexpression.

  3. PA28gamma in OSCC tumor tissues were significantly high expression than those in normal tissues.

  4. REGgamma acts in skin tumorigenesis mediating MAPK/p38 (show MAPK1 Antibodies) activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  5. Results show molecular cloning of a novel transcript variant encoding a truncated form of PA28G likely involved in cell cycle regulation and apoptosis.

  6. In a p53 (show TP53 Antibodies)-dominated cellular context, pro-apoptotic signaling might be overcome by PA28gamma-mediated caspase (show CASP3 Antibodies) inhibition.

  7. Our results suggest that the high expression of REGgamma might predict metastasis and poor prognosis in breast cancer.

  8. Increased PA28gamma sera levels were prognostic of disease activity in rheumatoid arthritis.

  9. Data suggest levels of gene expression of both PSME3 (proteasome activator subunit 3) and DUSP3 (dual specificity phosphatase 3 (show DUSP3 Antibodies)) are associated with susceptibility to Staphylococcus aureus infection/sepsis in humans and in mouse disease model.

  10. Examination of EC and normal endometrium specimens confirmed the oncogenic role of REGgamma, in that REGgamma was more highly overexpressed in p53 (show TP53 Antibodies)-positive specimens than in p53 (show TP53 Antibodies)-negative specimens.

PSME3 Antigen Profile

Antigen Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with PSME3

  • proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) (Psme3) antibody
  • proteasome (prosome, macropain) activator subunit 3 (Psme3) antibody
  • proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) (PSME3) antibody
  • proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) (psme3) antibody
  • AA410043 antibody
  • Ab2-371 antibody
  • AU020960 antibody
  • Ki antibody
  • PA28-gamma antibody
  • PA28G antibody
  • PA28gamma antibody
  • psme3b antibody
  • REG-GAMMA antibody
  • REGgamma antibody

Protein level used designations for anti-PSME3 (PSME3) Antibodies

11S regulator complex subunit gamma , REG-gamma , activator of multicatalytic protease subunit 3 , ki nuclear autoantigen , proteaseome (prosome, macropain) 28 subunit, 3 , proteasome activator 28 subunit gamma , proteasome activator complex subunit 3 , 11S regulator complex gamma subunit , Ki antigen , Ki nuclear autoantigen , PA28 gamma variant 5 , proteasome activator 28-gamma , PA28g , PA28gamma , proteasome activator subunit 3

GENE ID SPECIES
19192 Mus musculus
287716 Rattus norvegicus
10197 Homo sapiens
494719 Xenopus laevis
420017 Gallus gallus
480512 Canis lupus familiaris
397625 Sus scrofa
100336105 Bos taurus
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