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anti-Human CYP4F12 Antibodies:
anti-Mouse (Murine) CYP4F12 Antibodies:
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Human Polyclonal CYP4F12 Primary Antibody for EIA, WB - ABIN360265
Dhar, Sepkovic, Hirani, Magnusson, Lasker: Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11. in Journal of lipid research 2008
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Our results showed that HCV infection induced expression of CYP4F12 protein, which bound to the HCV replication complex to facilitate viral replication.
We conclude that CYP4F8 (show CYP4F8 Antibodies) and CYP4F12 catalyze epoxidation of 22:6n-3 and 22:5n-3, and CYP4F8 (show CYP4F8 Antibodies) omega3-hydroxylation of 22:5n-6.
3-hydroxystearate and 3-hydroxypalmitate are converted to omega-hydroxylated 3-OHDCA precursors in liver; CYP4F11 (show CYP4F11 Antibodies) and, to a lesser extent, CYP4F2 (show CYP4F2 Antibodies) catalyzed omega-hydroxylation of 3-hydroxystearate; CYP4F3b, CYP4F12, and CYP4A11 (show CYP4A11 Antibodies) had negligible activity.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid\\\\; however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19.
, cytochrome P450 4F12
, cytochrome P450, subfamily IVF, polypeptide 12