Browse our anti-PEX7 (PEX7) Antibodies

Full name:
anti-Peroxisomal Biogenesis Factor 7 Antibodies (PEX7)
On www.antibodies-online.com are 29 Peroxisomal Biogenesis Factor 7 (PEX7) Antibodies from 14 different suppliers available. Additionally we are shipping PEX7 Proteins (7) and many more products for this protein. A total of 39 PEX7 products are currently listed.
Synonyms:
DDBDRAFT_0206295, DDBDRAFT_0233068, DDB_0206295, DDB_0233068, MmPEX7, PBD9B, Peroxin-7, pex7, PTS2R, RCDP1, RD, zgc:103552
list all antibodies Gene Name GeneID UniProt
PEX7 18634 P97865
PEX7 308718  
PEX7 5191 O00628

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Most Popular Reactivities for anti-PEX7 (PEX7) Antibodies

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anti-Mouse (Murine) PEX7 Antibodies:

anti-Rat (Rattus) PEX7 Antibodies:

anti-Human PEX7 Antibodies:

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Top referenced anti-PEX7 Antibodies

  1. Human Polyclonal PEX7 Primary Antibody for IHC, ELISA - ABIN1535157 : Braverman, Steel, Lin, Moser, Moser, Valle: PEX7 gene structure, alternative transcripts, and evidence for a founder haplotype for the frequent RCDP allele, L292ter. in Genomics 2000 (PubMed)

  2. Human Polyclonal PEX7 Primary Antibody for WB - ABIN4891550 : Salcher, Hagenbuchner, Geiger, Seiter, Rainer, Kofler, Hermann, Kiechl-Kohlendorfer, Ausserlechner, Obexer: C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma. in Molecular cancer 2014 (PubMed)

More Antibodies against PEX7 Interaction Partners

Mouse (Murine) Peroxisomal Biogenesis Factor 7 (PEX7) interaction partners

  1. siRNA knockdown of PEX7 reduced iNOS (show NOS2 Antibodies) colocalization with the peroxisomal protein (show FNDC5 Antibodies) PMP70 (show ABCD3 Antibodies). Proteomic studies using MALDI-MS identified iNOS (show NOS2 Antibodies) association with the 50-kD ezrin (show EZR Antibodies) binding PDZ protein (show INADL Antibodies) (EBP50 (show SLC9A3R1 Antibodies)).

  2. Our data established that peroxisomal processing protease Tysnd1 (show TYSND1 Antibodies) is necessary to mediate the physiological functions of PTS2-containing substrates.

  3. Mutations in the Pex7 gene cause impaired neuronal migration and endochondral ossification.

Human Peroxisomal Biogenesis Factor 7 (PEX7) interaction partners

  1. This revealed a marked plasmalogen deficiency and a deficient fatty acid alpha-oxidation in the IHH (show IHH Antibodies) cells, due to a defect of PEX7, a cytosolic receptor protein required for peroxisomal import of a subset of peroxisomal proteins.

  2. our data suggest that insertion of the trimeric PEX5 (show PEX5 Antibodies)-PEX7-PTS2 protein complex into the DTM is probably accompanied by conformational alterations in PEX5 (show PEX5 Antibodies) to allow release of the PTS2 protein into the organelle matrix

  3. Mutation in the PEX7 Gene is associated with Rhizomelic Chondrodysplasia (show COL11A1 Antibodies) Punctata Type 1.

  4. the sequential formation of a highly stable trimeric complex involving cargo protein, PEX7 and PEX5L (show PEX5L Antibodies) stabilizes cargo binding and is a prerequisite for PTS2-mediated peroxisomal import.

  5. dysfunctional Pex7p, including mutants from RCDP patients, is degraded by a ubiquitin-dependent proteasomal pathway involving the CRL4A (Cullin4A-RING ubiquitin ligase) complex.

  6. Export of peroxisomal PEX7 back into the cytosol requires export of PEX5 (show PEX5 Antibodies).

  7. Structural requirements for interaction of peroxisomal targeting signal 2 and its receptor PEX7.

  8. Mutations in PEX7 gene is associated with Rhizomelic chondrodysplasia (show COL11A1 Antibodies) punctata.

  9. mutational spectrum in the PEX7 gene of 78 patients (including five pairs of sibs) clinically and biochemically diagnosed with RCDP type I

  10. The residual activity of mutant Pex7 protein in rhizomelic chondrodysplasia (show COL11A1 Antibodies) punctata patients and reduced amounts of normal Pex7 are associated with milder and variant phenotypes.

PEX7 Antigen Profile

Antigen Summary

This gene encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in this gene cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with more than one phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders, rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD).

Alternative names and synonyms associated with PEX7

  • peroxisomal biogenesis factor 7 (PEX7) antibody
  • peroxisomal biogenesis factor 7 (pex7) antibody
  • WD40 repeat-containing protein (pex7) antibody
  • peroxisomal biogenesis factor 7 (LOC100218417) antibody
  • peroxisomal biogenesis factor 7 (LOC100340758) antibody
  • peroxisomal biogenesis factor 7 (Pex7) antibody
  • DDBDRAFT_0206295 antibody
  • DDBDRAFT_0233068 antibody
  • DDB_0206295 antibody
  • DDB_0233068 antibody
  • MmPEX7 antibody
  • PBD9B antibody
  • Peroxin-7 antibody
  • pex7 antibody
  • PTS2R antibody
  • RCDP1 antibody
  • RD antibody
  • zgc:103552 antibody

Protein level used designations for PEX7

peroxisomal biogenesis factor 7 , peroxin 7 , peroxisome targeting signal type 2 receptor , peroxisomal targeting signal 2 receptor-like , PTS2 receptor , peroxin-7 , peroxisomal targeting signal 2 receptor , peroxisome biogenesis factor 7 , peroxisomal PTS2 receptor , peroxisome targeting signal 2 receptor

GENE ID SPECIES
463024 Pan troglodytes
548708 Xenopus (Silurana) tropicalis
705103 Macaca mulatta
8622229 Dictyostelium discoideum AX4
100218417 Taeniopygia guttata
100340758 Oryctolagus cuniculus
100406688 Callithrix jacchus
100454677 Pongo abelii
100596362 Nomascus leucogenys
18634 Mus musculus
308718 Rattus norvegicus
5191 Homo sapiens
541405 Danio rerio
421687 Gallus gallus
484000 Canis lupus familiaris
533077 Bos taurus
100736556 Cricetulus griseus
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