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Slc25a10 plays an important role in supplying malate for citrate transport required for fatty acid synthesis and its inhibition might effectively reduce lipid accumulation in adipose tissues
study identifies novel genes associated with insulin (show INS ELISA Kits) sensitivity in adipocytes in women independently of obesity. KFL15 and SLC25A10 are inhibitors of insulin (show INS ELISA Kits)-stimulated lipogenesis under conditions when glucose transport is the rate limiting step
the SLC25A10 carrier plays an important role in regulating redox homeostasis to protect confluent cells against oxidative stress.
Compares and contrasts all the known human SLC25A (show SLC25A25 ELISA Kits)* genes and includes functional information.
SLC25A10 is a target gene of the BACH1 (show BACH1 ELISA Kits) transcription factor according to ChIP-seq analysis in HEK (show EPHA3 ELISA Kits) 293 cells.
This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
peroxisomal membrane protein PMP34
, peroxisomal membrane protein, 34kDa), member 17
, solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
, dicarboxylate ion carrier
, mitochondrial dicarboxylate carrier
, solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 10
, solute carrier family 25 member 10
, dicarboxylate transporter), member 10