anti-Mouse (Murine) CXCR7 antibody for Intracellular Flow Cytometry

Recommended CXCR7 Antibody (supplied by: Log in to see )

Antigen
Chemokine (C-X-C Motif) Receptor 7 (CXCR7) Antibodies
  • BEST:LD12308
  • CG3171
  • Dmel\\CG3171
  • LD12308
  • Tre-1
  • anon-WO0170980.16
  • anon-WO0170980.17
  • anon-WO0170981.1
  • sctt
  • tre-1
  • tre1
  • CMKOR1
  • CXC-R7
  • CXCR-7
  • CXCR7
  • GPR159
  • RDC-1
  • RDC1
  • AW541270
  • Cmkor1
  • Cxcr7
  • Rdc1
  • Trapped in endoderm 1
  • G protein coupled receptor
  • atypical chemokine receptor 3
  • chemokine (C-X-C motif) receptor 7
  • Tre1
  • MmrVgp88
  • ACKR3
  • Ackr3
  • Cxcr7
  • CXCR7
Reactivity
Human, Mouse (Murine)
202
107
79
7
7
6
6
4
4
4
4
3
1
1
1
1
1
1
1
Host
Mouse
133
81
19
5
1
Clonality
Monoclonal
Conjugate
This CXCR7 antibody is conjugated to APC
14
11
10
10
10
10
9
9
8
8
7
7
6
4
4
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
130
98
54
41
26
26
16
7
5
5
3
3
2
1
1
Supplier
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Catalog No. ABIN2658746
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2658747 FACS ICFC APC Mouse IgG2b kappa Log in to see 8F11-M16 4

General

Antigen Chemokine (C-X-C Motif) Receptor 7 (CXCR7) Antibodies
Reactivity Human, Mouse (Murine)
(202), (107), (79), (7), (7), (6), (6), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(133), (81), (19), (5), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CXCR7 antibody is conjugated to APC
(14), (11), (10), (10), (10), (10), (9), (9), (8), (8), (7), (7), (6), (4), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
(130), (98), (54), (41), (26), (26), (16), (7), (5), (5), (3), (3), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-CXCR7 Antibody

Target Details CXCR7 Application Details Handling ProductDetails: References for anti-CXCR7 antibody (ABIN2658746) Images
Purification The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Clone 8F11-M16
Isotype IgG2b kappa

Target Details CXCR7

Product Details anti-CXCR7 Antibody Application Details Handling ProductDetails: References for anti-CXCR7 antibody (ABIN2658746) Images back to top
Antigen
Alternative Name CXCR7 (CXCR7 Antibody Abstract)
Background CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding of ligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors. CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal liver cells, and other cell types.
Pathways Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling

Application Details

Product Details anti-CXCR7 Antibody Target Details CXCR7 Handling ProductDetails: References for anti-CXCR7 antibody (ABIN2658746) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CXCR7 Antibody Target Details CXCR7 Application Details ProductDetails: References for anti-CXCR7 antibody (ABIN2658746) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

ProductDetails: References for anti-CXCR7 antibody (ABIN2658746)

Product Details anti-CXCR7 Antibody Target Details CXCR7 Application Details Handling Images back to top
Background publications

Biajoux, Bignon, Freitas, Martinez, Thelen, Lima, Jakez-Ocampo, Emilie, Llorente, Balabanian: "Expression of CXCL12 receptors in B cells from Mexican Mestizos patients with systemic Lupus erythematosus." in: Journal of translational medicine, Vol. 10, pp. 251, 2013

Soehnlein, Drechsler, Döring, Lievens, Hartwig, Kemmerich, Ortega-Gómez, Mandl, Vijayan, Projahn, Garlichs, Koenen, Hristov, Lutgens, Zernecke, Weber: "Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes." in: EMBO molecular medicine, Vol. 5, Issue 3, pp. 471-81, 2013

Burns, Summers, Wang, Melikian, Berahovich, Miao, Penfold, Sunshine, Littman, Kuo, Wei, McMaster, Wright, Howard, Schall: "A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development." in: The Journal of experimental medicine, Vol. 203, Issue 9, pp. 2201-13, 2006

Infantino, Moepps, Thelen: "Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 4, pp. 2197-207, 2006

Images

Product Details anti-CXCR7 Antibody Target Details CXCR7 Application Details Handling ProductDetails: References for anti-CXCR7 antibody (ABIN2658746) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody (APC) (ABIN2658746) anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody (APC)