Browse our GUCY1A3 (GUCY1A3) ELISA Kits

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Guanylate Cyclase 1, Soluble, alpha 3 ELISA Kits (GUCY1A3)
On www.antibodies-online.com are 1 Guanylate Cyclase 1, Soluble, alpha 3 (GUCY1A3) ELISA Kits from 1 different suppliers available. Additionally we are shipping GUCY1A3 Antibodies (46) and GUCY1A3 Proteins (6) and many more products for this protein. A total of 59 GUCY1A3 products are currently listed.
Synonyms:
1200016O07Rik, GC-SA3, GUC1A3, GUCA3, GUCSA3, Gucy1a1, gucy1a3, im:7136149, SGC, sgc1a1, zgc:112159
list all ELISA KIts Gene Name GeneID UniProt
GUCY1A3 2982 Q02108
Mouse GUCY1A3 GUCY1A3 60596 Q9ERL9
Rat GUCY1A3 GUCY1A3 497757  

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Human Guanylate Cyclase 1, Soluble, alpha 3 (GUCY1A3) interaction partners

  1. Rs7692387 is located in an intronic site that modulates GUCY1A3 promoter activity. The transcription factor ZEB1 (show ZEB1 ELISA Kits) binds preferentially to the nonrisk allele, leading to an increase in GUCY1A3 expression, higher sGC (show SGCB ELISA Kits) levels, and higher sGC (show SGCB ELISA Kits) activity after stimulation.

  2. Mutations in the GUCY1A3 gene are associated with moyamoya disease, achalasia, and hypertension.

  3. Expression of the alpha1-A680T sGC (show SGCB ELISA Kits) variant in reporter cells resulted in higher cyclic guanosine monophosphate production compared with the wild-type enzyme and the purified alpha1-A680T sGC (show SGCB ELISA Kits) exhibited enhanced sensitivity to nitric oxide in vitro.

  4. Dynamic interplay between hsp90 (show HSP90 ELISA Kits), apo (show C9orf3 ELISA Kits)-sGC (show SGCB ELISA Kits)-beta1, and sGC (show SGCB ELISA Kits)-alpha1 in response to NO is unprecedented and represent new steps by which cells can modulate the heme content and activity of sGC (show SGCB ELISA Kits) for signaling cascades.

  5. ZNF280B upregulates GUCY1A3 expression and downregulates TP53 (show TP53 ELISA Kits) in prostate cancer cells.

  6. homozygous mutations in GUCY1A3, which encodes the alpha1 subunit of soluble guanylate cyclase, the major receptor for nitric oxide, might play a role in moyamoya and achalasia

  7. The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclase

  8. GCS-alpha-1 regulation of p53 (show TP53 ELISA Kits) activity is important in prostate cancer biology and may represent an important mechanism of p53 (show TP53 ELISA Kits) down-regulation.

  9. We concluded that the alpha-subunit (show POLG ELISA Kits) and the beta(1)(191-619) domain exert structural strains on the heme domain.

  10. analysis of pharmacological response to direct sGC (show SGCB ELISA Kits) activators in coronary artery disease patients

Mouse (Murine) Guanylate Cyclase 1, Soluble, alpha 3 (GUCY1A3) interaction partners

  1. These data demonstrate that a reduction in cardiac sGC (show NPR1 ELISA Kits) activity worsens doxorubicin-induced cardiotoxicity in mice and identify sGC (show NPR1 ELISA Kits) as a potential therapeutic target.

  2. We suggest that Gucy1a3 activity promotes the phenotypic switching of smooth muscle cells from a contractile to a synthetic state, fostering the formation of atherosclerosis.

  3. The authors elucidated this dependency by showing that guanylate cyclase-1 is a novel rhodopsin (show RHO ELISA Kits)-binding protein.

  4. Cellular markers revealed that vascular SMC (show DYM ELISA Kits) differentiation decreased, whereas myofibroblast activation increased in the hyperoxic sGC (show NPR1 ELISA Kits)-alpha1 KO pup lung.

  5. Soluble guanylate cyclase alpha1-deficient mice: a novel murine model for primary open angle glaucoma.

  6. Male mice deficient in a NO receptor component, the alpha1 subunit of soluble guanylate cyclase (sGCalpha1), are prone to hypertension in some, but not all, mouse strains, suggesting that additional genetic factors contribute to the onset of hypertension

  7. These data suggests a novel physiological role for PDE5 (show PDE5A ELISA Kits) in restricting the effects of NOS3 (show NOS3 ELISA Kits)/sGC (show NPR1 ELISA Kits)/PKG (show PRKG1 ELISA Kits) signaling pathway to modulating beta-AR stimulated I(Ca), while limiting effects on cardiac contraction.[sGC (show NPR1 ELISA Kits)]

  8. Pressure overload results in translocation of sGC (show NPR1 ELISA Kits) out of membrane microdomains, depressing NO/heme-dependent activation in the heart, consistent with enhanced oxidation.

  9. findings identify a crucial role of the NO/sGCalpha1beta1/cGMP pathway in modulating lymphatic vessel function [soluble guanylate cyclase alpha1beta1]

  10. RD3 (show RD3 ELISA Kits) mediates the export of GC1 from the endoplasmic reticulum to endosomal vesicles, and that the C terminus of GC1 is required for RD3 (show RD3 ELISA Kits) binding

Cow (Bovine) Guanylate Cyclase 1, Soluble, alpha 3 (GUCY1A3) interaction partners

  1. We concluded that the alpha-subunit (show POLG ELISA Kits) and the beta(1)(191-619) domain exert structural strains on the heme domain.

  2. The N-terminal region of nitric oxide-sensitive guanylyl cyclase alpha 1 subunit(amino acids 61-128) is mandatory for quantitative dimerization.

GUCY1A3 Antigen Profile

Antigen Summary

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Alternative names and synonyms associated with GUCY1A3

  • guanylate cyclase 1, soluble, alpha 3 (GUCY1A3) Elisa Kit
  • guanylate cyclase 1, soluble, alpha 3 (gucy1a3) Elisa Kit
  • si:dkey-264b2.3 (si:dkey-264b2.3) Elisa Kit
  • guanylate cyclase 1, soluble, alpha 3 (LOC100223563) Elisa Kit
  • soluble guanylyl cyclase alpha subunit (gucy1a3) Elisa Kit
  • guanylate cyclase 1, soluble, alpha 3 (Gucy1a3) Elisa Kit
  • 1200016O07Rik Elisa Kit
  • GC-SA3 Elisa Kit
  • GUC1A3 Elisa Kit
  • GUCA3 Elisa Kit
  • GUCSA3 Elisa Kit
  • Gucy1a1 Elisa Kit
  • gucy1a3 Elisa Kit
  • im:7136149 Elisa Kit
  • SGC Elisa Kit
  • sgc1a1 Elisa Kit
  • zgc:112159 Elisa Kit

Protein level used designations for GUCY1A3

guanylate cyclase 1, soluble, alpha 3 , guanylate cyclase soluble subunit alpha-3 , soluble guanylate cyclase large subunit alpha 1 , soluble guanylate cyclase 1 alpha 3 , si:dkey-264b2.3 , guanylate cyclase soluble subunit alpha-3-like , soluble guanylyl cyclase alpha subunit , GC-S-alpha-1 , GCS-alpha-1 , GCS-alpha-3 , soluble guanylate cyclase large subunit , alpha 1 sGC , Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase) , Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase) , NO-sensitive GC alpha 1 subunit , guanylate cyclase soluble subunit alpha-1 , larger subunit of soluble guanylyl cyclase , nitric oxide-sensitive guanylyl cyclase alpha 1 subunit

GENE ID SPECIES
422407 Gallus gallus
550420 Danio rerio
553100 Sus scrofa
699365 Macaca mulatta
100017038 Monodelphis domestica
100069573 Equus caballus
100150025 Danio rerio
100172608 Pongo abelii
100223563 Taeniopygia guttata
100294641 Ovis aries
100396127 Callithrix jacchus
100547213 Meleagris gallopavo
100581660 Nomascus leucogenys
100608597 Pan troglodytes
100049177 Oryzias latipes
2982 Homo sapiens
60596 Mus musculus
497757 Rattus norvegicus
482663 Canis lupus familiaris
281216 Bos taurus
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