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Human IGFBP2 ELISA Kit for Sandwich ELISA - ABIN624998
Kratz, Lake, Ljungström, Forsberg, Haegerstrand, Gidlund: Effect of recombinant IGF binding protein-1 on primary cultures of human keratinocytes and fibroblasts: selective enhancement of IGF-1 but not IGF-2-induced cell proliferation. in Experimental cell research 1992
Show all 11 Pubmed References
Mouse (Murine) IGFBP2 ELISA Kit for Sandwich ELISA - ABIN625401
Kang, Kim, Kim, Lee, Kim, Seo, Bae, Oh, Song, Ahn, Im: Regulation of IGFBP-2 expression during fasting. in The Biochemical journal 2015
Human IGFBP2 ELISA Kit for Sandwich ELISA - ABIN816448
Patel, Ellis, Howard, Boufraqech, Gara, Zhang, Quezado, Nilubol, Kebebew: Analysis of IGF and IGFBP as Prognostic Serum Biomarkers for Adrenocortical Carcinoma. in Annals of surgical oncology 2014
In human whole blood cells, methylation of IGFBP2 at the homologous CpG site was increased in obese men with impaired glucose tolerance. In conclusion, our data show that increased methylation of hepatic Igfbp2 during infancy predicts the development of fatty liver later in life and is linked to deterioration of glucose metabolism.
IGFBP2 not only is a driver of glioma progression and a prognostic factor but is also required for tumour maintenance and thus represents a viable therapeutic target in the treatment of glioma.
that the lacking the Arg-Gly-Asp (show C3 ELISA Kits)-domain has a major influence on the pleiotropic effects of IGFBP-2 and suggest that somatic growth and time of sexual maturity or somatic growth and life expectancy are less closely related than thought previously
Data (including data from studies in knockout mice) suggest, as osteoblasts differentiate, early induction of AMPK (show PRKAA1 ELISA Kits) in response to IGF-I (show IGF1 ELISA Kits)/IGFBP-2 is followed by suppression of AMPK (show PRKAA1 ELISA Kits) as required for osteogenesis; activation of AMPK (show PRKAA1 ELISA Kits) stimulates autophagy.
estrogen deficiency has a profound effect on body and bone composition in the absence of IGFBP-2 and may be related to changes in fibroblast growth factor 21 (show FGF21 ELISA Kits).
Impaired glucose clearance in female IGFBP-2 transgenic mice is dependent on the presence of the RGD motif and that translocation of GLUT4 (show SLC2A4 ELISA Kits) in the muscle may be regulated by IGFBP-2 via RGD-dependent mechanisms.
protein(s) that associated with RPTPbeta (show PTPRZ1 ELISA Kits) in response to IGF-I (show IGF1 ELISA Kits) and IGFBP-2 in vascular smooth muscle cells
The results suggest that stimulation of differentiation is an important mechanism by which IGFBP-2 regulates the acquisition of normal bone mass in mice.
PPARalpha (show PPARA ELISA Kits) controls IGF-1 (show IGF1 ELISA Kits) signalling through the up-regulation of hepatic Igfbp-2 transcription during fasting.
IGFBP2 is a critical cell-autonomous factor that promotes the survival and migration of acute leukemia cells.
We verified that NFIA (show NFIA ELISA Kits) binds to the IGFBP2 promoter and transcriptionally enhances IGFBP2 expression levels. We identified that NFIA (show NFIA ELISA Kits)-mediated IGFBP2 signaling pathways are involved in miR (show MLXIP ELISA Kits)-302b-induced glioma cell death.
Insulin-like growth factor binding protein 2 potentiates glioblastoma tumor growth by the activation of the beta-catenin (show CTNNB1 ELISA Kits) pathway through its C-terminal domain, and their coexpression possibly contributes to worse patient prognosis.
mechanistic investigations defined insulin-like growth factor binding protein 2 (IGFBP2)as a direct and functional downstream target of microRNA-592, which was involved in the microRNA-592-mediated tumor-suppressive effects in glioma cells.
IGFBP2 and IGFBP3 (show IGFBP3 ELISA Kits) may serve as compensatory biomarkers for CA19-9. Early diagnosis with this marker combination may improve the prognosis of invasive ductal adenocarcinoma of pancreas patients.
Data suggest that circulating insulin-like growth factor-binding protein 2 (IGFBP2) has potential as a biomarker predicting prognosis for gastric cancer patients.
Together, this study validated that T-2 toxin exposure might promote the progression of KBD by inducing chondrocyte injury, suppressing matrix synthesis and accelerating cellular catabolism through IGFBP2. Therefore, this research will elucidate a new insight about how T-2 toxin participate in the pathogenesis of KBD.
IGFBP2 protein levels are altered in type 2 diabetes mellitus patients and associated with cardiovascular disease risk factors.
The monoclonal gammopathy of undetermined significance and multiple myeloma patients displayed a significant increase in intact IGFBP-2 and decrease in intact IGFBP-3 (show IGFBP3 ELISA Kits) in the circulation compared to control individuals.
In patients with malignant and borderline ovarian tumors, the level of IGFBP-2 was higher than in healthy women and in patients with benign ovarian tumors.
Results suggest that IGFBP-2 is associated with production performance in pigs.
Five novel SNPs were identified in IGFBP2, two of which had significant associations with fertility (age at conception in heifers and commencement of luteal activity) and 305-day milk yield in lactation 1.
The present study suggests that the insulin (show INS ELISA Kits) like growth factor (IGF) system or imbalances between IGF and IGF binding (show HTRA1 ELISA Kits) proteins may be involved in cystic ovary disease of cattle.
in preovulatory follicles, PAPP-A (show PAPPA ELISA Kits) is responsible for IGF-dependent IGFBP-2 degradation
spatial and temporal patterns of expression of IGFBP-2 and -3 were markedly altered in the placentomes of nuclear transfer pregnancies
protein that binds to Igf-I and Igf-II
insulin-like growth factor binding protein 2, 36kDa
, IGF-binding protein 2
, insulin-like growth factor-binding protein 2
, IGF binding protein 2
, insulin-like growth factor-binding protein-2, IGFBP-2