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Human IGFBP2 ELISA Kit for Sandwich ELISA - ABIN624998
Kratz, Lake, Ljungström, Forsberg, Haegerstrand, Gidlund: Effect of recombinant IGF binding protein-1 on primary cultures of human keratinocytes and fibroblasts: selective enhancement of IGF-1 but not IGF-2-induced cell proliferation. in Experimental cell research 1992
Show all 11 references for ABIN624998
Mouse (Murine) IGFBP2 ELISA Kit for Sandwich ELISA - ABIN1889295
Ehrenborg, Vilhelmsdotter, Bajalica, Larsson, Stern, Koch, Brøndum-Nielsen, Luthman: Structure and localization of the human insulin-like growth factor-binding protein 2 gene. in Biochemical and biophysical research communications 1991
Show all 2 references for ABIN1889295
IGFBP2 not only is a driver of glioma progression and a prognostic factor but is also required for tumour maintenance and thus represents a viable therapeutic target in the treatment of glioma.
that the lacking the Arg-Gly-Asp (show C3 ELISA Kits)-domain has a major influence on the pleiotropic effects of IGFBP-2 and suggest that somatic growth and time of sexual maturity or somatic growth and life expectancy are less closely related than thought previously
Data (including data from studies in knockout mice) suggest, as osteoblasts differentiate, early induction of AMPK (show PRKAA1 ELISA Kits) in response to IGF-I (show IGF1 ELISA Kits)/IGFBP-2 is followed by suppression of AMPK (show PRKAA1 ELISA Kits) as required for osteogenesis; activation of AMPK (show PRKAA1 ELISA Kits) stimulates autophagy.
estrogen deficiency has a profound effect on body and bone composition in the absence of IGFBP-2 and may be related to changes in fibroblast growth factor 21 (show FGF21 ELISA Kits).
Impaired glucose clearance in female IGFBP-2 transgenic mice is dependent on the presence of the RGD motif and that translocation of GLUT4 (show SLC2A4 ELISA Kits) in the muscle may be regulated by IGFBP-2 via RGD-dependent mechanisms.
protein(s) that associated with RPTPbeta (show PTPRZ1 ELISA Kits) in response to IGF-I (show IGF1 ELISA Kits) and IGFBP-2 in vascular smooth muscle cells
The results suggest that stimulation of differentiation is an important mechanism by which IGFBP-2 regulates the acquisition of normal bone mass in mice.
PPARalpha (show PPARA ELISA Kits) controls IGF-1 (show IGF1 ELISA Kits) signalling through the up-regulation of hepatic Igfbp-2 transcription during fasting.
IGFBP2 is a critical cell-autonomous factor that promotes the survival and migration of acute leukemia cells.
IGFBP-2 plays an IGF-I (show IGF1 ELISA Kits)-dependent and -independent role in the brain's acute (neuroprotection) and chronic (tissue remodeling) response to hypoxic-ischemic injury.
Together, this study validated that T-2 toxin exposure might promote the progression of KBD by inducing chondrocyte injury, suppressing matrix synthesis and accelerating cellular catabolism through IGFBP2. Therefore, this research will elucidate a new insight about how T-2 toxin participate in the pathogenesis of KBD.
IGFBP2 protein levels are altered in type 2 diabetes mellitus patients and associated with cardiovascular disease risk factors.
The monoclonal gammopathy of undetermined significance and multiple myeloma patients displayed a significant increase in intact IGFBP-2 and decrease in intact IGFBP-3 (show IGFBP3 ELISA Kits) in the circulation compared to control individuals.
In patients with malignant and borderline ovarian tumors, the level of IGFBP-2 was higher than in healthy women and in patients with benign ovarian tumors.
IGFBP2 and SOCS3 (show SOCS3 ELISA Kits) were up-regulated in Kashin-Beck disease chondrocytes and decreased with increasing selenium concentrations. IGFBP2 expressed highest in the middle zone of KBD cartilage, SOCS3 (show SOCS3 ELISA Kits) expressed higher in the middle and deep zone. IGFBP2 and SOCS3 (show SOCS3 ELISA Kits) may be the biomarkers for KBD diagnosis and evaluating the effect of selenium supplement.
Serum IGFBP-1 (show IGFBPI ELISA Kits) and -2 are increased in idiopathic pulmonary fibrosis and IGFBP-2 may be reduced by anti-fibrosing therapy.
There was a positive correlation between the IGFBP2 levels of and those of inflammatory mediators in HIV Infections.
IGFBP-2 overexpression in HUVECs promoted endothelial progenitor cells(EPC (show TCF21 ELISA Kits))-endothelial adhesion. The RGD motif in its C-domain is required for interaction with integrin alpha5beta1.
Serum IGFBP2 reflects disease activity and renal pathology changes in lupus nephritis.
Data show that modulation of insulin like growth factor binding protein 2 (IGFBP2) expression affects proliferation, motility, and chemosensitization of eophageal adenocarcinoma (EAC (show CYLD ELISA Kits)) cells in a serum-dependent manner.
Results suggest that IGFBP-2 is associated with production performance in pigs.
Five novel SNPs were identified in IGFBP2, two of which had significant associations with fertility (age at conception in heifers and commencement of luteal activity) and 305-day milk yield in lactation 1.
The present study suggests that the insulin (show INS ELISA Kits) like growth factor (IGF) system or imbalances between IGF and IGF binding (show HTRA1 ELISA Kits) proteins may be involved in cystic ovary disease of cattle.
in preovulatory follicles, PAPP-A (show PAPPA ELISA Kits) is responsible for IGF-dependent IGFBP-2 degradation
spatial and temporal patterns of expression of IGFBP-2 and -3 were markedly altered in the placentomes of nuclear transfer pregnancies
protein that binds to Igf-I and Igf-II
insulin-like growth factor binding protein 2, 36kDa
, IGF-binding protein 2
, insulin-like growth factor-binding protein 2
, IGF binding protein 2
, insulin-like growth factor-binding protein-2, IGFBP-2