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Browse our DYRK3 Proteins (DYRK3)

Full name:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 Proteins (DYRK3)
On www.antibodies-online.com are 7 Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) Proteins from 5 different suppliers available. Additionally we are shipping DYRK3 Antibodies (78) and DYRK3 Kits (1) and many more products for this protein. A total of 91 DYRK3 products are currently listed.
Synonyms:
BC006704, CSA2, DYRK3, DYRK5, HMG-CoAR, hYAK3-2, MGC89944, RED, REDK
list all proteins Gene Name GeneID UniProt
DYRK3 15357 Q01237
DYRK3 8444 O43781
DYRK3 304775 Q4V8A3

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DYRK3 Proteins (DYRK3) by Origin

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Top referenced DYRK3 Proteins

  1. Human DYRK3 Protein expressed in Baculovirus infected Insect Cells - ABIN2003308 : Becker, Weber, Wetzel, Eirmbter, Tejedor, Joost: Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases. in The Journal of biological chemistry 1998 (PubMed)
    Show all 2 references for ABIN2003308

More Proteins for DYRK3 Interaction Partners

Mouse (Murine) Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) interaction partners

  1. these studies designate sterol-accelerated degradation of HMGCR (show HMGCR Proteins) as a potential therapeutic target for prevention of atherosclerosis and associated cardiovascular disease.

  2. To eludicate the mechanisms underlying statin myotoxicity and HMGCR (show HMGCR Proteins) function in skeletal muscle, we developed the skeletal muscle-specific (show EIF3K Proteins) HMGCR (show HMGCR Proteins) knockout mice.

  3. High-dose simvastatin inhibits HMGCoA reductase (show HMGCR Proteins) and prevents experimental hyperinflation lung injury by angioprotective and anti-inflammatory effects.

  4. TSH can regulate the phosphorylation of HMGCR (show HMGCR Proteins) via AMPK (show PRKAA1 Proteins).

  5. HMGCR (show HMGCR Proteins) proteasomal-degradation by IFN strictly requires the synthesis of endogenous 25-Hydroxycholesterol.

  6. Increased cholesterol synthesis mediated by HMGCoA (show HMGCS2 Proteins)-R under inflammatory stress may be one of the mechanisms for intracellular lipid accumulation and statin resistance.

  7. we consistently observe involvement of gp78 (show AMFR Proteins) in Insig-1 degradation, we find no substantive evidence to support roles for either gp78 (show AMFR Proteins) or TRC8 (show RNF139 Proteins) in the robust sterol-accelerated degradation of HMG-CoA reductase (show HMGCR Proteins).

  8. Study identified the dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) as a protein with the ability to condense P-granule-like speckles in the cytosol and to prevent stress granule dissolution via its N-terminal domain when it is in a kinase-inactive form.

  9. Hepatocyte HMGCR (show HMGCR Proteins) is essential for the survival of mice, and its abrogation elicits hepatic steatosis with jaundice and hypoglycemia.

  10. Linalool reduces the expression of 3-hydroxy-3-methylglutaryl CoA reductase via sterol regulatory element binding protein-2- and ubiquitin-dependent mechanisms.

Human Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3) interaction partners

  1. Study identified the dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) as a protein with the ability to condense P-granule-like speckles in the cytosol and to prevent stress granule dissolution via its N-terminal domain when it is in a kinase-inactive form.

  2. the lipid raft-dependent endocytosis process mediates C. neoformans internalization into HBMEC and the CD44 (show CD44 Proteins) protein of the hosts, cytoskeleton, and intracellular kinase-DYRK3 are involved in this process

  3. DYRK1A (show DYRK1A Proteins) and DYRK3 promote cell survival through phosphorylation and activation of SIRT1 (show SIRT1 Proteins).

  4. DYRK3 has roles in kinase activation, binding to CREB (show CREB1 Proteins), and hematopoietic progenitor cell survival

  5. DYRK3, expression is strong in erythroid cells and testis, but is also detected in adult kidney and liver

  6. DYRK3 dual-specificity kinase attenuates erythropoiesis during anemia

DYRK3 Protein Profile

Protein Summary

This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with DYRK3

  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (DYRK3)
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (dyrk3)
  • 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Hmgcr)
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (Dyrk3)
  • IK cytokine (Ik)
  • BC006704 protein
  • CSA2 protein
  • DYRK3 protein
  • DYRK5 protein
  • HMG-CoAR protein
  • hYAK3-2 protein
  • MGC89944 protein
  • RED protein
  • REDK protein

Protein level used designations for DYRK3

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 , 3-hydroxy-3-methylglutaryl-CoA reductase , 3-hydroxy-3-methylglutaryl-coenzyme A reductase , HMG-CoA reductase , dual specificity tyrosine-phosphorylation-regulated kinase 3 , dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5 , protein kinase Dyrk3 , regulatory erythroid kinase , ual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 , Ik factor , chondrosarcoma-associated protein 2 , cytokine IK , protein Red

GENE ID SPECIES
480010 Canis lupus familiaris
419846 Gallus gallus
469142 Pan troglodytes
493520 Xenopus (Silurana) tropicalis
496058 Xenopus laevis
695163 Macaca mulatta
15357 Mus musculus
8444 Homo sapiens
505149 Bos taurus
226419 Mus musculus
304775 Rattus norvegicus
291659 Rattus norvegicus
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