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Browse our anti-KCNQ1 (KCNQ1) Antibodies

Full name:
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 Antibodies (KCNQ1)
On www.antibodies-online.com are 140 Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) Antibodies from 18 different suppliers available. Additionally we are shipping KCNQ1 Proteins (4) and KCNQ1 Kits (2) and many more products for this protein. A total of 156 KCNQ1 products are currently listed.
Synonyms:
ATFB1, ATFB3, AW559127, CG12215, CG12915, CG33135, dKCNQ, Dmel\\CG33135, JLNS1, KCNA8, Kcna9, KCNQ1, kcnq1-A, kqt-3, Kv1.9, Kv7.1, KvLQT-1, KvLQT1, LQT, LQT1, RWS, SQT2, WRS, xkvlqt1, zgc:158384
list all antibodies Gene Name GeneID UniProt
KCNQ1 3784 P51787
KCNQ1 84020 Q9Z0N7
KCNQ1 16535 P97414

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Most Popular Reactivities for anti-KCNQ1 (KCNQ1) Antibodies

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anti-Human KCNQ1 Antibodies:

anti-Rat (Rattus) KCNQ1 Antibodies:

anti-Mouse (Murine) KCNQ1 Antibodies:

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Top referenced anti-KCNQ1 Antibodies

  1. Hamster Monoclonal KCNQ1 Primary Antibody for AA, ICC - ABIN361766 : Kurokawa, Bankston, Kaihara, Chen, Furukawa, Kass: KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel. in Channels (Austin, Tex.) 2009 (PubMed)
    Show all 3 references for ABIN361766

  2. Human Monoclonal KCNQ1 Primary Antibody for FACS, ELISA - ABIN969227 : Jiang, Xu, Wang, Toyoda, Liu, Zhang, Robinson, Tseng: Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2. in The Journal of biological chemistry 2009 (PubMed)

  3. Human Polyclonal KCNQ1 Primary Antibody for ELISA, WB - ABIN451757 : Yasuda, Miyake, Horikawa, Hara, Osawa, Furuta, Hirota, Mori, Jonsson, Sato, Yamagata, Hinokio, Wang, Tanahashi, Nakamura, Oka, Iwasaki, Iwamoto, Yamada, Seino, Maegawa, Kashiwagi, Takeda, Maeda, Shin et al.: Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. ... in Nature genetics 2009 (PubMed)

  4. Hamster Monoclonal KCNQ1 Primary Antibody for AA, ICC - ABIN2483167 : Lang, Vallon, Knipper, Wangemann: Functional significance of channels and transporters expressed in the inner ear and kidney. in American journal of physiology. Cell physiology 2007 (PubMed)

  5. Human Polyclonal KCNQ1 Primary Antibody for FACS, WB - ABIN652891 : Holm, Gudbjartsson, Arnar, Thorleifsson, Thorgeirsson, Stefansdottir, Gudjonsson, Jonasdottir, Mathiesen, Njølstad, Nyrnes, Wilsgaard, Hald, Hveem, Stoltenberg, Løchen, Kong, Thorsteinsdottir, Stefansson: Several common variants modulate heart rate, PR interval and QRS duration. in Nature genetics 2010 (PubMed)

  6. Human Polyclonal KCNQ1 Primary Antibody for EIA, WB - ABIN953014 : Nakajo, Ulbrich, Kubo, Isacoff: Stoichiometry of the KCNQ1 - KCNE1 ion channel complex. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

  7. Cow (Bovine) Polyclonal KCNQ1 Primary Antibody for IHC, WB - ABIN2776085 : Zhou, Tan, Paz, Ogawa, Chou, Hayashi, Nihei, Fishbein, Chen, Lin, Chen: Antiarrhythmic effects of beta3-adrenergic receptor stimulation in a canine model of ventricular tachycardia. in Heart rhythm : the official journal of the Heart Rhythm Society 2008 (PubMed)

  8. Cow (Bovine) Polyclonal KCNQ1 Primary Antibody for WB - ABIN2776340 : Du, Li, Tsai, You, Xia: Characterization of binding site of closed-state KCNQ1 potassium channel by homology modeling, molecular docking, and pharmacophore identification. in Biochemical and biophysical research communications 2005 (PubMed)

More Antibodies against KCNQ1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. the single KCNQ channel in Drosophila (dKCNQ) has similar electrophysiological properties to neuronal KCNQ2 (show KCNQ2 Antibodies)/3

  2. Data show that Drosophila KCNQ (dKCNQ) is a slowly activating and slowly-deactivating K(+) current open at sub-threshold potentials that has similar properties to neuronal KCNQ2 (show KCNQ2 Antibodies)/3 with some features of the cardiac KCNQ1/KCNE1 (show KCNE1 Antibodies).

  3. A maternal contribution of KCNQ protein and/or mRNA is essential for early embryonic development

Rabbit Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. The enhanced sensitivity of KCNQ1 gain-of-function mutations for HMR (show NR4A1 Antibodies)-1556 suggests the possibility of selective therapeutic targeting, and a potential proof of principle for genotype-specific treatment of this heritable arrhythmia.

  2. There were substantial transmural gradients in Cav1.2 (show CACNA1C Antibodies), KChIP2 (show KCNIP2 Antibodies), ERG (show KCNH2 Antibodies), KvLQT1, Kir2.1 (show KCNJ2 Antibodies), NCX1 (show SLC8A1 Antibodies), SERCA2a (show ATP2A2 Antibodies) and RyR2 (show RYR2 Antibodies) at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

Human Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. Sphingomyelin synthase 1 (show SGMS1 Antibodies) positively regulates KCNQ1/KCNE1 (show KCNE1 Antibodies) channel density in a protein kinase D (show PRKD1 Antibodies)-dependent manner.

  2. Receptor Species-dependent Desensitization Controls KCNQ1/KCNE1 (show KCNE1 Antibodies) K+ Channels as Downstream Effectors of Gq Protein-coupled Receptors.(

  3. conclude that KCNQ1 is a promising biomarker for prediction of disease recurrence and may aid stratification of patients with stage II MSS (show SIL1 Antibodies) colon cancer for adjuvant chemotherapy

  4. present genetic and phenotypic data for 4 family members across 2 generations who all have evidence of prolonged QT interval and left ventricular noncompaction in association with a pathogenic mutation in KCNQ1, and discuss the potential mechanisms of this association

  5. Study provides evidence that SNPs of JMJD1C (show JMJD1C Antibodies) and KCNQ1 are prospectively associated with the risk of type 2 diabetes (T2D) in Korean population. Additionally, CDKAL1 (show CDKAL1 Antibodies) may not be associated with T2D onset over the age of 40.

  6. Chinese family with dual LQT1 and HCM phenotypes associated with tetrad heterozygous mutations in KCNQ1, MYH7 (show MYH7 Antibodies), MYLK2 (show MYLK2 Antibodies), and TMEM70 (show TMM70 Antibodies) mutations.

  7. the rs2237892 SNP in KCNQ1 may be a susceptible locus for T2DM in female Kazakh individuals. Furthermore, CT/TT are susceptible genotypes and T is a susceptible allele at this locus. However, the KCNQ1 rs2237895 SNP does not appear to be associated with T2DM in the Chinese Kazakh population.

  8. After adjustment for age, sex, and BMI, rs163182 in KCNQ1 and rs7612463 in UBE2E2 were found to be associated with Type 2 Diabetes Mellitus risk in Chinese Han population.

  9. 176 cases of drowning were screened for mutations in the exons 3, 5, 6, 7, and 8 of the KCNQ1; no variation to the published sequence could be found in the exonic DNA in any of the cases clearly disproving an involvement of these mutation clusters in cases of drowning

  10. A stoichiometry of 4:4 between the alpha KCNE1 (show KCNE1 Antibodies) and the beta KCNQ1-subunits has been established.

Xenopus laevis Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. KCNE1 (show KCNE1 Antibodies)/KCNQ1 was expressed in Xenopus oocytes with and without beta-catenin (show CTNNB1 Antibodies). Confocal microscopy revealed that beta-catenin (show CTNNB1 Antibodies) enhanced the KCNE1 (show KCNE1 Antibodies)/KCNQ1 protein abundance in the cell membrane.

  2. results indicate that AMPK (show PRKAA2 Antibodies) inhibits KCNQ1 activity by promoting Nedd4-2 (show NEDD4L Antibodies)-dependent channel ubiquitination and retrieval from the plasma membrane.

  3. S1 constrains S4 in the voltage sensor domain of Kv7.1 K+ channels

  4. characterize a new component of the early bioelectrical circuit: the potassium channel (show KCNAB2 Antibodies) KCNQ1 and its accessory subunit KCNE1 (show KCNE1 Antibodies)

  5. Slow delayed rectifier potassium currents mediated by mutant KCNQ1(Y111C) or KCNQ1(L114P) are paradoxically reduced by serum- and glucocorticoid-inducible kinase 1.

  6. phenylboronic acid (PBA) activates KCNQ1/KCNE1 (show KCNE1 Antibodies) complexes

Mouse (Murine) Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

  1. we investigated the effects of KCNQ1 A340E, a loss-of-function mutant. J343 mice bearing KCNQ1 A340E demonstrated a much higher 24-h intake of electrolytes (potassium, sodium, and chloride). KCNQ1, therefore, is suggested to play a central role in electrolyte metabolism. KCNQ1 A340E, with the loss-of-function phenotype, may dysregulate electrolyte homeostasis

  2. The electrophysiological effects of BACE1 (show BACE Antibodies) on KCNQ1 reported here were independent of its enzymatic activity.

  3. Loss of methylation at the Kcnq1 imprinted gDMD was strongly associated with trophoblast giant cell (TGC (show TGM2 Antibodies)) expansion.

  4. Data show that disruption of potassium voltage-gated channel, KQT-like subfamily Q, member1 (KCNQ1) results in increased expression of cyclin-dependent kinase inhibitor 1C (Cdkn1c (show CDKN1C Antibodies)) only when the mutation is on the paternal allele.

  5. S3 mutations in KCNQ1 cause diverse kinetic defects in I(Ks), affecting opening and closing properties, and can account for LQT1 (show ARFGAP1 Antibodies) phenotypes.

  6. Characterization of the imprinted Kcnq1 domain which contains a differentially methylated region in intron 11 of Kcnq1.

  7. KCNQ1, KCNE2 (show KCNE2 Antibodies), and SMIT1 (show SLC5A3 Antibodies) form reciprocally regulating complexes that affect neuronal excitability.

  8. low expression of KCNQ1 expression was significantly associated with poor overall survival.

  9. Which participates in the allelic repression of Kcnq1.

  10. H(+)-K(+)-ATPase/KCNQ1 reside in independent intracytoplasmic membrane compartments, or membrane domains, and upon activation of parietal cells, both membrane proteins are transported, possibly via Rab11-positive recycling endosomes, to apical membranes.

Guinea Pig Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) interaction partners

KCNQ1 Antigen Profile

Antigen Summary

This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with KCNQ1

  • KCNQ potassium channel (KCNQ) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 1 (KCNQ1) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1) antibody
  • voltage gated potassium channel subunit (kcnq1) antibody
  • KvLQT1 voltage-gated delayed rectifier potassium channel (KVLQT1) antibody
  • potassium voltage-gated channel subfamily KQT member 1-like (LOC100626134) antibody
  • potassium voltage-gated channel, KQT-like subfamily, member 1 (Kcnq1) antibody
  • potassium voltage-gated channel, subfamily Q, member 1 (Kcnq1) antibody
  • ATFB1 antibody
  • ATFB3 antibody
  • AW559127 antibody
  • CG12215 antibody
  • CG12915 antibody
  • CG33135 antibody
  • dKCNQ antibody
  • Dmel\\CG33135 antibody
  • JLNS1 antibody
  • KCNA8 antibody
  • Kcna9 antibody
  • KCNQ1 antibody
  • kcnq1-A antibody
  • kqt-3 antibody
  • Kv1.9 antibody
  • Kv7.1 antibody
  • KvLQT-1 antibody
  • KvLQT1 antibody
  • LQT antibody
  • LQT1 antibody
  • RWS antibody
  • SQT2 antibody
  • WRS antibody
  • xkvlqt1 antibody
  • zgc:158384 antibody

Protein level used designations for KCNQ1

CG33135-PC , CG33135-PD , CG33135-PE , CG33135-PF , CG33135-PG , CG33135-PH , CG33135-PI , CG33135-PJ , CG33135-PK , KCNQ-PC , KCNQ-PD , KCNQ-PE , KCNQ-PF , KCNQ-PG , KCNQ-PH , KCNQ-PI , KCNQ-PJ , KCNQ-PK , KCNQ-type K[+] channel , potassium voltage-gated channel, KQT-like subfamily, member 1 , potassium channel protein KCNQ1 , potassium voltage-gated channel, subfamily Q, member 1 , voltage gated potassium channel subunit , potassium voltage-gated channel subfamily KQT member 1 , KvLQT1 voltage-gated delayed rectifier potassium channel , Potassium voltage-gated channel subfamily KQT member 1 , IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1 , kidney and cardiac voltage dependend K+ channel , slow delayed rectifier channel subunit , voltage-gated potassium channel subunit Kv7.1 , potassium channel protein (KvLQT1) , ventricular voltage-gated K+ channel pore-forming subunit KCNQ1 , KQT-like 1 , Voltage-gated potassium channel subunit Kv7.1 , potassium channel protein , IKs producing slow voltage-gated potassium channel subunit alpha xKvLQT1

GENE ID SPECIES
36071 Drosophila melanogaster
100034129 Equus caballus
100145329 Xenopus (Silurana) tropicalis
100187466 Ciona intestinalis
557498 Danio rerio
100009443 Oryctolagus cuniculus
100626134 Sus scrofa
3784 Homo sapiens
483669 Canis lupus familiaris
397326 Sus scrofa
784876 Bos taurus
84020 Rattus norvegicus
423090 Gallus gallus
101092644 Felis catus
373746 Xenopus laevis
16535 Mus musculus
100379230 Cavia porcellus
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