Browse our Vanin 1 Proteins (VNN1)

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Vanin 1 Proteins (VNN1)
On are 22 Vanin 1 (VNN1) Proteins from 8 different suppliers available. Additionally we are shipping Vanin 1 Antibodies (53) and Vanin 1 Kits (23) and many more products for this protein. A total of 106 Vanin 1 products are currently listed.
HDLCQ8, Tiff66, V-1, vanin-1, vnn1.1
list all proteins Gene Name GeneID UniProt
VNN1 22361 Q9Z0K8
VNN1 8876 O95497
VNN1 29142  

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Vanin 1 Proteins (VNN1) by Origin

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Top referenced Vanin 1 Proteins

  1. Human VNN1 Protein expressed in Wheat germ - ABIN1325026 : Dammanahalli, Stevens, Terkeltaub: Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. in PLoS ONE 2012 (PubMed)

More Proteins for Vanin 1 Interaction Partners

Mouse (Murine) Vanin 1 (VNN1) interaction partners

  1. The data demonstrate that vanin-1/pantetheinase controls fibrosis, vasculopathy, autoimmunity, and oxidative stress in Systemic sclerosis (SSc (show CYP11A1 Proteins)).

  2. oxidized LDL (Ox-LDL) can significantly induce VNN1 expression through an ERK1/2/cyclooxygenase-2 (COX-2 (show PTGS2 Proteins))/PPARalpha (show PPARA Proteins) signaling pathway.

  3. absence of vanin-1 activity improves insulin (show INS Proteins) sensitivity.

  4. serum pantetheinas, encoded by the VNN1 gene, level regulates erythrocyte life span and modulates the risk of developing complicated malaria.

  5. Results suggest an important role for VNN1 in regulating hepatic gluconeogenesis.

  6. Data indicate that genetic ablation of the Vanin-1 (Vnn1) gene in SF-1 (NR5A1 (show NR5A1 Proteins)) transgenic mice significantly reduced the severity of neoplastic lesions in the adrenal cortex.

  7. Microparticle internalization required the interaction of the ectoenzyme Vanin-1 (VNN1), an abundant surface protein on the microparticles, with lipid raft domains of endothelial cells.

  8. Epithelial vanin-1 controls inflammation-driven carcinogenesis in the colitis-associated colon cancer model.

  9. Data show that Vanin-1(-/-) mice better controlled inflammatory reaction and intestinal injury in either acute (NSAID administration) or chronic (Schistosoma infection) inflammation.

  10. Data show that Vanin-1(-/-) mice, which lack cysteamine in tissues, exhibit resistance to oxidative injury induced by whole-body gamma-irradiation or paraquat.

Human Vanin 1 (VNN1) interaction partners

  1. findings suggest that the metabolic pathway catalyzed by VNN1 pantetheinase plays a suppressive role in IAV infection in the respiratory tract, especially in severe conditions under hypercytokinemia

  2. Data show that G protein-coupled receptor (show ADRA1A Proteins), family C, group 5, member A (show CXCL14 Proteins) protein (GPRC5A (show GPRC5A Proteins)) regulates oxidative stress through vanin 1 protein (VNN1).

  3. These data suggest that urinary vanin-1 is an early predictive biomarker for decline in eGFR (show EGFR Proteins) in patients with urothelial carcinoma after dosing of cisplatin

  4. serum pantetheinas, encoded by the VNN1 gene, level regulates erythrocyte life span and modulates the risk of developing complicated malaria.

  5. VNN1 contributes to corticosteroid responsiveness, and changes in VNN1 nasal epithelial mRNA expression and VNN1 promoter methylation might be clinically useful biomarkers of treatment response in asthmatic children.

  6. Our study provides strong biological evidence for the association of the identified SNP with BP and suggests that vanin-1 misfolding and degradation are the underlying molecular mechanism.

  7. show that hepatic vanin-1 is under extremely sensitive regulation by PPARalpha (show PPARA Proteins) and that plasma vanin activity could serve as a readout of changes in PPARalpha (show PPARA Proteins) activity in human subjects

  8. The X-ray crystal structure of human vanin 1 at 2.25 A resolution is presented, which is the first reported structure from the vanin family, as well as a crystal structure of vanin 1 bound to a specific inhibitor.

  9. Serum vanin-1 levels may be low in the end-stage renal failure and transiently increase after transplant owing to transient renal function deterioration, which does not lead to elevation of serum creatinine levels in renal transplant patients.

  10. Our results suggest that vanin-1 can distinguish between chronic responders and non-responders ITP (show ITPA Proteins) patients as well as between newly diagnosed ITP (show ITPA Proteins) patients and healthy controls.

Vanin 1 (VNN1) Protein Profile

Protein Summary

This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.

Alternative names and synonyms associated with Vanin 1 (VNN1)

  • vanin 1 (VNN1)
  • vanin 1 (vnn1)
  • vanin 1 (LOC100217969)
  • vascular non-inflammatory molecule 2-like (VNN2)
  • vanin 1 (Vnn1)
  • HDLCQ8 protein
  • Tiff66 protein
  • V-1 protein
  • vanin-1 protein
  • vnn1.1 protein

Protein level used designations for Vanin 1 Proteins (VNN1)

vanin 1 , vanin 1, gene 1 , pantetheinase , pantetheine hydrolase , vanin-1 , vascular non-inflammatory molecule 1 , vannin 1 , TIFF66

421701 Gallus gallus
496642 Xenopus (Silurana) tropicalis
100217969 Taeniopygia guttata
100220807 Taeniopygia guttata
22361 Mus musculus
8876 Homo sapiens
526704 Bos taurus
442973 Canis lupus familiaris
397246 Sus scrofa
29142 Rattus norvegicus
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