Browse our Glutathione S-Transferase mu 2 (Muscle) Proteins (GSTM2)

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Glutathione S-Transferase mu 2 (Muscle) Proteins (GSTM2)
On are 26 Glutathione S-Transferase mu 2 (Muscle) (GSTM2) Proteins from 10 different suppliers available. Additionally we are shipping Glutathione S-Transferase mu 2 (Muscle) Antibodies (56) and Glutathione S-Transferase mu 2 (Muscle) Kits (10) and many more products for this protein. A total of 97 Glutathione S-Transferase mu 2 (Muscle) products are currently listed.
GST4, GSTA4, Gstb-2, Gstb2, GSTIV, GSTM, GSTM2-2, GTHMUS
list all proteins Gene Name GeneID UniProt
GSTM2 24424 P08010
GSTM2 2946 P28161
GSTM2 14863 P15626

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Top referenced Glutathione S-Transferase mu 2 (Muscle) Proteins

  1. Human GSTM2 Protein expressed in Escherichia coli (E. coli) - ABIN667223 : Bogaards, van Ommen, van Bladeren: Purification and characterization of eight glutathione S-transferase isoenzymes of hamster. Comparison of subunit composition of enzymes from liver, kidney, testis, pancreas and trachea. in The Biochemical journal 1992 (PubMed)
    Show all 2 references for 667223

  2. Human GSTM2 Protein expressed in Escherichia coli (E. coli) - ABIN2004991 : Ebert, Klinder, Peters, Schäferhenrich, Sendt, Scheele, Pool-Zobel: Expression of glutathione S-transferases (GSTs) in human colon cells and inducibility of GSTM2 by butyrate. in Carcinogenesis 2003 (PubMed)

More Proteins for Glutathione S-Transferase mu 2 (Muscle) Interaction Partners

Human Glutathione S-Transferase mu 2 (Muscle) (GSTM2) interaction partners

  1. The absence of GSTM1 (show GSTM1 Proteins) and GSTT1 (show GSTT1 Proteins) genes increases the risk of lung cancer because of radon exposure.

  2. the absence of GSTM1 (show GSTM1 Proteins) activity can be compensated for by the overexpression of GSTM2.

  3. demonstrated that the GSTM1 (show GSTM1 Proteins) and GSTT1 (show GSTT1 Proteins) null genotype may be associated with an increased risk of Hepatocellular carcinoma (HCC (show FAM126A Proteins)) and that individuals having the combination of both defective GST (show SLCO6A1 Proteins) genotypes may be more susceptible to developing HCC (show FAM126A Proteins)

  4. High expression of GSTM1 (show GSTM1 Proteins) and GSTM4 (show GSTM4 Proteins), along with increased endogenous reduced glutathione levels, help to maintain a more reduced state of cytochrome c (show CYCS Proteins) which decreases apoptosis thus contributing to methotrexate resistance in human MCF7 breast cancer cells.

  5. GST-M2 exhibited high frequency of promoter hypermethylation in lung cancer cells, CpG hypermethylation abated Sp1 binding to the GST-M2 promoter in lung cancer

  6. it was noted that the alpha-6 helix of GST-C plays a stabilising role in the fold of this domain. By destabilising the conformation of GST-C, an increase in cell translocation efficiency of up to approximately 2-fold was observed.

  7. analysis of active-site residues and modulation of catalytic functions in GST-M2

  8. High GSTM2 is associated with mesenchymal stem-like cells derived from ovarian teratoma (show DND1 Proteins).

  9. it is unlikely that glutathione S-transferases GSTA2 (show GSTa2 Proteins), GSTM2, GSTO1 (show GSTO1 Proteins), GSTO2 (show GSTO2 Proteins), and GSTZ1 (show GSTZ1 Proteins) participate in breast cancer susceptibility.

  10. The structure of helix 6 in the carboxyl-terminal fold is critical to GSTM2-2's inhibitory action on the cardiac ryanodine receptor.

Mouse (Murine) Glutathione S-Transferase mu 2 (Muscle) (GSTM2) interaction partners

  1. Gstm2 is highly expressed in the uterine luminal epithelium during preimplantation period and up-regulated by progesterone.

Glutathione S-Transferase mu 2 (Muscle) (GSTM2) Protein Profile

Protein Summary

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Alternative names and synonyms associated with Glutathione S-Transferase mu 2 (Muscle) (GSTM2)

  • glutathione S-transferase mu 2 (Gstm2)
  • glutathione S-transferase mu 2 (muscle) (GSTM2)
  • glutathione S-transferase mu 2 (muscle) (Gstm2)
  • glutathione S-transferase, mu 2 (Gstm2)
  • glutathione S-transferase2 (gst2)
  • Protein GST-4 (gst-4)
  • GST4 protein
  • GSTA4 protein
  • Gstb-2 protein
  • Gstb2 protein
  • GSTIV protein
  • GSTM protein
  • GSTM2-2 protein
  • GTHMUS protein

Protein level used designations for GSTM2

GST 4-4 , GST Yb2 , GSTM2-2 , Glutathione-S-transferase mu type 2 (Yb2) , Glutathione-S-transferase, mu type 2 (Yb2) , glutathione S-transferase M2 , glutathione S-transferase Mu 2 , glutathione S-transferase Yb-2 , glutathione S-transferase Yb2 subunit , GST class-mu 2 , GST, muscle , S-(hydroxyalkyl)glutathione lyase M2 , glutathione S-alkyltransferase M2 , glutathione S-aralkyltransferase M2 , glutathione S-aryltransferase M2 , glutathione S-transferase 4 , glutathione S-transferase M1 , glutathione S-transferase M2 (muscle) , GST class-mu , GST-CL2 , GSTM1-1 , glutathione S-transferase 2 , glutathione S-transferases CL2 , GST Mu I , glutathione S-transferase Mu 1 , glutathione transferase , GST 5-5 , glutathione S-transferase pmGT2 , glutathione-S-transferase, mu 2 , GRMZM2G132093 , GST class-phi member 4 , GST-27 , GST-IV , PCO060686 , PCO060686_ov , glutathione S-transferase IV , hypothetical protein

24424 Rattus norvegicus
2946 Homo sapiens
395976 Gallus gallus
100009073 Oryctolagus cuniculus
100732167 Cavia porcellus
14863 Mus musculus
542311 Zea mays
177886 Caenorhabditis elegans
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