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Browse our AATF Proteins (AATF)

Full name:
Apoptosis Antagonizing Transcription Factor Proteins (AATF)
On www.antibodies-online.com are 13 Apoptosis Antagonizing Transcription Factor (AATF) Proteins from 8 different suppliers available. Additionally we are shipping AATF Antibodies (101) and AATF Kits (30) and many more products for this protein. A total of 152 AATF products are currently listed.
Synonyms:
4933415H02Rik, 5830465M17Rik, AATF, cb109, Che-1, CHE1, Ded, sb:cb109, Trb, wu:fc13d05, zgc:162071
list all proteins Gene Name GeneID UniProt
AATF 26574 Q9NY61
AATF 56321 Q9JKX4
AATF 114512 Q9QYW0

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AATF Proteins (AATF) by Origin

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More Proteins for AATF Interaction Partners

Human Apoptosis Antagonizing Transcription Factor (AATF) interaction partners

  1. loss of Che-1 (show BCHE Proteins) inhibits proliferation and promotes apoptosis in MG-63 cells by decreasing the level of mutant p53 (show TP53 Proteins)

  2. It was concluded that PARP-1 (show PARP1 Proteins) was involved in the DNA damage repair induced by HQ via increasing the accumulation of apoptosis antagonizing transcription factor through PARylation.

  3. These results confirm Che-1 as an important regulator of p53 activity and suggest Che-1 to be a promising yet attractive drug target for cancer therapy.

  4. In the face of high glucose threat, mitochondrial UCP2 (show UCP2 Proteins) gene expression is regulated by miR (show MLXIP Proteins)-2909 and AATF.

  5. This mutant AATF along with its interactome consisting of SP1 (show PSG1 Proteins), DNMT3B (show DNMT3B Proteins) and Par-4 (show PAWR Proteins) ensures cancer cell DNA methylation (show HELLS Proteins) required for down-regulation of tumor suppressor genes.

  6. HIPK2 depletion strongly decreases Che-1 ubiquitylation and degradation.

  7. Che-1 (show BCHE Proteins) expression correlates with the progression of multiple myeloma and is required for cell growth and survival.Che-1 controls mTOR (show FRAP1 Proteins) through the induction of Redd1 (show DDIT4 Proteins) and Deptor (show DEPTOR Proteins), two important repressors of mTOR (show FRAP1 Proteins).

  8. Cell proliferation decreased by 41% which was accompanied by apoptosis induction in 30% MCF-7 cells after AATF gene knockdown.

  9. Che-1 (show BCHE Proteins) depletion abolishes the ability of Chk1 (show CHEK1 Proteins) to bind pericentrin and to localize at centrosomes, which, in its turn, deregulates the activation of centrosomal cyclin B-Cdk1 (show CDK1 Proteins) and advances entry into mitosis.

  10. These results identify AATF as a nucleolar-confined c-Jun (show JUN Proteins) cofactor whose expression levels and spatial distribution determine the stress-induced activity of c-Jun (show JUN Proteins) and the levels of c-Jun (show JUN Proteins)-mediated apoptosis.

Mouse (Murine) Apoptosis Antagonizing Transcription Factor (AATF) interaction partners

  1. These results identify AATF as a nucleolar-confined c-Jun (show JUN Proteins) cofactor whose expression levels and spatial distribution determine the stress-induced activity of c-Jun (show JUN Proteins) and the levels of c-Jun (show JUN Proteins)-mediated apoptosis.

  2. AATF is an endogenous antagonist of Par-4 (show F2RL3 Proteins) activity and an effective inhibitor of aberrant amyloid beta 1-42 production and secretion under apoptotic conditions.

  3. Che-1 as a new Pin1 (show PIN1 Proteins) and HDM2 target and confirm its important role in the cellular response to DNA damage.

AATF Protein Profile

Protein Summary

The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.

Alternative names and synonyms associated with AATF

  • apoptosis antagonizing transcription factor (AATF)
  • apoptosis antagonizing transcription factor (aatf)
  • Apoptosis antagonizing transcription factor (BFR2)
  • apoptosis antagonizing transcription factor (NAEGRDRAFT_56916)
  • apoptosis antagonizing transcription factor (Aatf)
  • 4933415H02Rik protein
  • 5830465M17Rik protein
  • AATF protein
  • cb109 protein
  • Che-1 protein
  • CHE1 protein
  • Ded protein
  • sb:cb109 protein
  • Trb protein
  • wu:fc13d05 protein
  • zgc:162071 protein

Protein level used designations for AATF

apoptosis antagonizing transcription factor , protein AATF , Apoptosis antagonizing transcription factor , protein AATF-like , apoptosis-antagonizing transcription factor , rb-binding protein Che-1 , traube protein

GENE ID SPECIES
100057601 Equus caballus
454601 Pan troglodytes
549062 Xenopus (Silurana) tropicalis
559477 Danio rerio
717586 Macaca mulatta
4852007 Scheffersomyces stipitis CBS 6054
8852758 Naegleria gruberi strain NEG-M
100404639 Callithrix jacchus
100451788 Pongo abelii
100580798 Nomascus leucogenys
26574 Homo sapiens
480595 Canis lupus familiaris
417653 Gallus gallus
786013 Bos taurus
56321 Mus musculus
114512 Rattus norvegicus
100381006 Xenopus laevis
100513881 Sus scrofa
100732839 Cavia porcellus
100356226 Oryctolagus cuniculus
101109984 Ovis aries
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