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Human Monoclonal ARHGDIA Primary Antibody for ICC, FACS - ABIN969501
Ronneburg, Span, Kantelhardt, Dittmer, Schunke, Holzhausen, Sweep, Dittmer: Rho GDP dissociation inhibitor alpha expression correlates with the outcome of CMF treatment in invasive ductal breast cancer. in International journal of oncology 2009
Show all 2 references for ABIN969501
Human Polyclonal ARHGDIA Primary Antibody for FACS, IHC (p) - ABIN389429
Qiao, Holian, Lee, Huang, Zhang, Lum: Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA. in American journal of physiology. Cell physiology 2008
Human Monoclonal ARHGDIA Primary Antibody for ELISA, WB - ABIN559944
Liu, Huang, Xing, Xi, Zhuang, Yuan, Yang, Zhao: Comparative proteomic analysis on human L-02 liver cells treated with varying concentrations of trichloroethylene. in Toxicology and industrial health 2008
Human Polyclonal ARHGDIA Primary Antibody for IHC, ELISA - ABIN1531733
Xiao, Lin, Ke, Lin, Lin, Lin: 14-3-3τ promotes breast cancer invasion and metastasis by inhibiting RhoGDIα. in Molecular and cellular biology 2014
Increased expression of bovine Rho GDIalpha (show GDI1 Antibodies) led to electrophysiological alterations that resulted in atrial arrhythmias and AV conduction abnormalities in transgenic mice, whereas ventricular contractile function was largely preserved.
that inhibition of Ca2 (show CA2 Antibodies)+ channel activity by overexpression of Rho GDI-alpha is mediated by inhibition of RhoA (show RHOA Antibodies) in cardiac myocytes
Rho GDP association inhibitor (GDI) alpha- mediated disruption of Rho GTPase (show RACGAP1 Antibodies) activity impairs lens fiber cell migration, elongation and survival.
MiR (show MLXIP Antibodies)-25 is activated by the WNT (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway, and exerts its pro-metastatic function by directly inhibiting the Rho GDP dissociation inhibitor alpha (RhoGDI1). Downregulation of RhoGDI1 enhances expression of Snail (show SNAI1 Antibodies), thereby promoting EMT (show ITK Antibodies).
RIP2 (show ARHGEF28 Antibodies) and RhoGDI bind to p75(NTR (show NGFR Antibodies)) death domain at partially overlapping epitopes with over 100-fold difference in affinity, revealing the mechanism by which RIP2 (show ARHGEF28 Antibodies) recruitment displaces RhoGDI upon ligand binding.
Downregulation of RhoGDI could be a critical mechanism of breast tumor development, which may involve the hyperactivation of Rho GTPases and upregulation of COX-2 (show COX2 Antibodies) activity.
RHOGDI alpha acetylation interferes with Rho signaling, resulting in alteration of cellular filamentous actin.
the present study has identified loss of ARHGDIA contributed to the processes of hepatic tumorigenesis, in particular invasion and metastasis
new mechanistic insights into the understanding of essential role of SUMOylation at Lys (show LYZ Antibodies)-138 in RhoGDIalpha's biological function.
By directly targeting the Rho GDP dissociation inhibitor alpha (RhoGDI1) and activated leukocyte cell adhesion molecule (ALCAM (show ALCAM Antibodies)).
A significant trend was identified between loss of RhoGDI expression in hepatocellular carcinoma and worsening clinical prognosis.
Our findings suggest that RhoGDI overexpression is a predictor of distant metastasis and plays an important role in the progression of hepatocellular carcinoma
the association of RhoGDIalpha with TROY (show TNFRSF19 Antibodies) contributed to TROY (show TNFRSF19 Antibodies)-dependent RhoA (show RHOA Antibodies) activation and neurite outgrowth inhibition after Nogo (show RTN4 Antibodies)-66 stimulation.
Integrin beta 8 and PTP-PEST (show PTPN12 Antibodies) form protein complexes at the leading edge of migrating cells and balance patterns of Rac1 and Cdc42 (show CDC42 Antibodies) signaling by controlling the subcellular localization and phosphorylation status of Rho GDP dissociation inhibitor 1.
RhoGDalpha controls ENaC expression and activity via Rac1.
Data found that CCK (show CCK Antibodies)-induced PKCalpha (show PKCa Antibodies) phosphorylation on RhoGDI1 at Ser96 releases RhoA (show RHOA Antibodies) and Rac1 from RhoGDI1 to facilitate Rho GTPases signaling.
we demonstrated the regulation of targeting/accumulation of the RhoGDIalpha-Rac1 complex to phagosomes
how the beta cell utilizes RhoGDI for differential Cdc42 and Rac1 cycling
Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis (show XIRP1 Antibodies) and inhibits cardiomyocyte proliferation.
analysis of inhibitory and shuttling functions of rhoGDI-3 (show ARHGDIG Antibodies) and rhoGDI-1
isoprenylcysteine carboxylmethyltransferase (show ICMT Antibodies) regulates Rac1 activity by controlling the interaction of Rac1 with RhoGDI through TNFA (show TNF Antibodies)
Aplysia Ras-related homologs (ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA (Leffers et al., 1993
rho GDP-dissociation inhibitor 1
, Rho GDP dissociation inhibitor (GDI) alpha
, rho GDI 1
, rho-GDI alpha
, Rho GDI alpha