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Browse our ARHGEF18 Proteins (ARHGEF18)

Full name:
rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 Proteins (ARHGEF18)
On www.antibodies-online.com are 5 rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) Proteins from 4 different suppliers available. Additionally we are shipping ARHGEF18 Antibodies (75) and many more products for this protein. A total of 83 ARHGEF18 products are currently listed.
Synonyms:
AI467246, arhgef18, D030053O22Rik, P114-RhoGEF, wu:fc21e04, wu:fj05f11, zgc:85686
list all proteins Gene Name GeneID UniProt
ARHGEF18 23370 Q6ZSZ5
ARHGEF18 102098 Q6P9R4
Rat ARHGEF18 ARHGEF18 304193  

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ARHGEF18 Proteins (ARHGEF18) by Origin

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More Proteins for ARHGEF18 Interaction Partners

Human rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) interaction partners

  1. CRB3A recruits p114RhoGEF and its activator Ehm2 to the cell periphery using both functional motifs of its cytoplasmic tail and increases RhoA (show RHOA Proteins) activation levels.

  2. LKB1 (show STK11 Proteins) and p114RhoGEF control RhoA (show RHOA Proteins) activity in bronchial epithelial cells to promote apical junction assembly.

  3. Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion.

  4. In its regulation of the circumferential actomyosin tensile system, Lulu2 interacts with and activates p114RhoGEF at apical cell-cell junctions.

  5. Data indicate that p114RhoGEF is a component of a junction-associated Rho signalling module that drives spatially restricted activation of RhoA (show RHOA Proteins) to regulate junction formation and epithelial morphogenesis.

  6. p114-RhoGEF and Lfc (show ARHGEF2 Proteins) are critically involved in Wnt-3a (show WNT3A Proteins)- and Dvl (show DVL2 Proteins)-induced RhoA (show RHOA Proteins) activation and neurite retraction in N1E-115 cells.

  7. data showed that the novel guanine nucleotide exchange factor (show RASGRF1 Proteins) p114RhoGEF regulates the activity of RhoA (show RHOA Proteins) and Rac1, and that Gbetagamma subunits of heterotrimeric G proteins are activators of p114RhoGEF under physiological conditions

ARHGEF18 Protein Profile

Protein Summary

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with ARHGEF18

  • rho/rac guanine nucleotide exchange factor (GEF) 18a (arhgef18a)
  • Rho/Rac guanine nucleotide exchange factor (GEF) 18 (ARHGEF18)
  • rho/rac guanine nucleotide exchange factor (GEF) 18 (Arhgef18)
  • rho/rac guanine nucleotide exchange factor (GEF) 18 (ARHGEF18)
  • AI467246 protein
  • arhgef18 protein
  • D030053O22Rik protein
  • P114-RhoGEF protein
  • wu:fc21e04 protein
  • wu:fj05f11 protein
  • zgc:85686 protein

Protein level used designations for ARHGEF18

rho/rac guanine nucleotide exchange factor (GEF) 18 , Rho/Rac guanine nucleotide exchange factor (GEF) 18 , Rho-specific guanine nucleotide exchange factor p114 , 114 kDa Rho-specific guanine nucleotide exchange factor , P114-RHO-GEF , Rho/Rac guanine nucleotide exchange factor 18 , SA-RhoGEF , p114RhoGEF , rho guanine nucleotide exchange factor 18 , septin-associated RhoGEF

GENE ID SPECIES
407987 Danio rerio
468693 Pan troglodytes
707510 Macaca mulatta
100027283 Monodelphis domestica
100538655 Meleagris gallopavo
23370 Homo sapiens
484991 Canis lupus familiaris
102098 Mus musculus
420132 Gallus gallus
100511004 Sus scrofa
522521 Bos taurus
304193 Rattus norvegicus
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