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Browse our rho Guanine Nucleotide Exchange Factor (GEF) 4 Proteins (ARHGEF4)

Full name:
rho Guanine Nucleotide Exchange Factor (GEF) 4 Proteins (ARHGEF4)
On www.antibodies-online.com are 4 rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) Proteins from 2 different suppliers available. Additionally we are shipping rho Guanine Nucleotide Exchange Factor (GEF) 4 Antibodies (43) and many more products for this protein. A total of 52 rho Guanine Nucleotide Exchange Factor (GEF) 4 products are currently listed.
Synonyms:
9330140K16Rik, ARHGEF4, Asef, ASEF1, ENSMUSG00000070955, GEF4, STM6
list all proteins Gene Name GeneID UniProt
ARHGEF4 50649 Q9NR80
ARHGEF4 226970 Q7TNR9
Rat ARHGEF4 ARHGEF4 301334  

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rho Guanine Nucleotide Exchange Factor (GEF) 4 Proteins (ARHGEF4) by Origin

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More Proteins for rho Guanine Nucleotide Exchange Factor (GEF) 4 Interaction Partners

Human rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) interaction partners

  1. These data demonstrate, that in addition to microtubule-independent Tiam1 (show TIAM1 Proteins) activation, HGF (show HGF Proteins) engages additional microtubule- and APC (show APC Proteins)-dependent pathway of Asef activation.

  2. these results demonstrate potent anti-inflammatory effects by HGF (show HGF Proteins) and delineate a key role of Asef in the mediation of the HGF (show HGF Proteins) barrier protective and anti-inflammatory effects.

  3. Expression of Asef was associated with lower estimated glomerular filtration rate in kidney disease.

  4. Expression of ARHGEF4 (Rho guanine nucleotide exchange factor 4) is restricted to the brain and may regulate the actin cytoskeletal network, cell morphology and migration, and neuronal function

  5. structures thus elucidate the molecular mechanism of Asef recognition by APC (show APC Proteins)

  6. Forced expression of Asef in vitro induced and maintained proliferation of haemaopoietic progenitor cells and co-operated with TEL-AML1 greatly to enhance proliferation and haemopoietic colony size

  7. Positive role of Tyr94 phosphorylation in EGF-induced Asef activation following the activation of Rac1.

  8. Asef and APC (show APC Proteins) function downstream of HGF (show HGF Proteins) and PI3-kinase (show PIK3CA Proteins), and play critical roles in growth factor-mediated regulation of cell morphology and migration

Mouse (Murine) rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) interaction partners

  1. Asef has a role in HGF (show HGF Proteins)-mediated protection against endothelial hyperpermeability and lung injury.

  2. these results demonstrate potent anti-inflammatory effects by HGF (show HGF Proteins) and delineate a key role of Asef in the mediation of the HGF (show HGF Proteins) barrier protective and anti-inflammatory effects.

  3. Asef and Asef2 (show SPATA13 Proteins) are required for adenoma formation in Apc (show APC Proteins)(Min/+)mice.

rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) Protein Profile

Protein Summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.

Alternative names and synonyms associated with rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4)

  • Rho guanine nucleotide exchange factor (GEF) 4 (ARHGEF4)
  • Rho guanine nucleotide exchange factor 4 (arhg4)
  • Rho guanine nucleotide exchange factor (GEF) 4 (Arhgef4)
  • 9330140K16Rik protein
  • ARHGEF4 protein
  • Asef protein
  • ASEF1 protein
  • ENSMUSG00000070955 protein
  • GEF4 protein
  • STM6 protein

Protein level used designations for ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4 , Rho guanine nucleotide exchange factor 4 , rho guanine nucleotide exchange factor 4 , rho guanine nucleotide exchange factor 4-like , APC-stimulated guanine nucleotide exchange factor 1 , APC-stimulated guanine nucleotide exchange factor

GENE ID SPECIES
424761 Gallus gallus
470538 Pan troglodytes
483856 Canis lupus familiaris
505852 Bos taurus
100067370 Equus caballus
100380335 Salmo salar
100392066 Callithrix jacchus
100432711 Pongo abelii
100470646 Ailuropoda melanoleuca
100544917 Meleagris gallopavo
50649 Homo sapiens
226970 Mus musculus
301334 Rattus norvegicus
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