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Rat (Rattus) HDAC1 ELISA Kit for Sandwich ELISA - ABIN432608
Bang, Ambavade, Jagdale, Adkar, Waghmare, Ambavade: Lacosamide reduces HDAC levels in the brain and improves memory: Potential for treatment of Alzheimer's disease. in Pharmacology, biochemistry, and behavior 2015
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Treatment of the haplotype Npr1 (show NPR1 ELISA Kits)(+/-) mice with histone deacetylase inhibitors significantly lowered blood pressure and reduced the renal inflammation and fibrosis involving the interactive roles of HDAC1/2, NF-kappaB (show NFKB1 ELISA Kits) (p65 (show NFkBP65 ELISA Kits)), and STAT1 (show STAT1 ELISA Kits).
Acetylation-dependent control of global poly(A) RNA degradation by CBP/p300 (show CREBBP ELISA Kits) and HDAC1-HDAC2 has been described.
Here, we use transgenic lines to define the in vivo relevance of HDAC1 and identify calcineurin-dependent serine dephosphorylation as the signal modulating the neurotoxic role of HDAC1 in response to neurotoxic stimuli.
In line with the acetyltransferase activity of p300 (show NOTCH1 ELISA Kits), H3K27 acetylation was reduced after HDACi and resulted in the formation of heterochromatin in the PTGES1 gene. In conclusion, HDAC (show HDAC3 ELISA Kits) activity maintains PTGES1 expression by recruiting p300 (show NOTCH1 ELISA Kits) to its gene
provide new insight into the upstream regulation of Sap90/Psd95 (show DLG4 ELISA Kits)-associated protein 3 (show HSPB3 ELISA Kits) and establish the essential role of striatal Hdac1, Hdac2 (show HDAC2 ELISA Kits) and MeCP2 for suppression of repetitive behaviors
Taken together, Fam60a is an essential core subunit of a variant Sin3a-Hdac (show HDAC3 ELISA Kits) complex in embryonic stem cells that is required to promote rapid proliferation and prevent unscheduled differentiation.
HDAC1 may be an essential epigenetic regulator of the transition from progenitor cells to terminally differentiated photoreceptors
Knockdown of HDAC1 recovered Bdnf (show BDNF ELISA Kits) and Pvalb (show PVALB ELISA Kits) gene transcription and also prevented the decrease of inhibitory synapses accompanying whisker deprivation
HDAC1 binds PAX6 (show PAX6 ELISA Kits) and protein-protein interaction leads to transcriptional repression of PAX6 (show PAX6 ELISA Kits) target genes during mouse retinal development
PC3/Tis21 (show BTG2 ELISA Kits) associates with HDAC1, HDAC4 (show HDAC5 ELISA Kits), and HDAC9 (show HDAC9 ELISA Kits) in vivo, in fibroblast cells.
These results reveal the presence of an MSI1 (show MSI1 ELISA Kits)-HDA19 complex that fine-tunes abscissic acid signaling in Arabidopsis.
HDC1 is a ubiquitously expressed nuclear protein that interacts with at least two deacetylases (HDA6 (show HDAC6 ELISA Kits) and HDA19), promotes histone deacetylation, and attenuates derepression of genes under water stress.
HDA19 and HSL1 may act together to repress seed maturation gene expression during germination. HDA19 and HSL1 may play a vital role during embryogenesis.
findings show that AP2 represses its target genes by physically recruiting the co-repressor TOPLESS and the histone deacetylase HDA19
HDA6 (show HDAC6 ELISA Kits) and HDA19 may play a redundant role in modulating seed germination and salt stress response, as well as ABA- and salt stress-induced gene expression in Arabidopsis.[HDA19]
Data suggest that AtHD1 is a nuclear protein (show HEMGN ELISA Kits) and possesses histone deacetylase activities responsible for global transcriptional regulation important to plant growth and development.
These results suggest that acetylation of specific histone Lys (show LYZ ELISA Kits) residues, regulated by GCN5, TAF1, and HD1, is required for light-regulated gene expression.
These results suggest that during germination in Arabidopsis, HDA6 (show HDAC6 ELISA Kits) and HDA19 redundantly regulate the repression of embryonic properties directly or indirectly via repression of embryo-specific gene function.
Rpd3 accumulates in the nucleolus in the early stage of starvation, upregulates rRNA synthesis, maintains the polysome amount for translation, and finally increases stress tolerance proteins, such as autophagy-related proteins, to acquire starvation stress resistance.
Hdac1/Rpd3 functions together with self-renewal transcriptional repressors to maintain the erm (show MSN ELISA Kits) immature intermediate neural progenitors enhancer in an inactive but poised state in neuroblasts.
This study tested the longevity effects of RPD3 on multiple nutrient levels.
Rpd3 deacetylase in the heart plays a significant role in cardiac function and longevity to systemically modulate the fly's response to the environment
the Atro-Rpd3 complex plays a conserved role to function as a Ci(R) corepressor.
Study shows that Fru (show ZBTB22 ELISA Kits) forms a complex with the transcriptional cofactor Bonus (Bon), which, in turn, recruits either of two chromatin regulators, Histone deacetylase 1 (HDAC1), which masculinizes individual sexually dimorphic neurons, or Heterochromatin protein 1a (HP1a (show CBX5 ELISA Kits)), which demasculinizes them.
The dose of Rpd3 is critical for normal long-term memory.
Work suggests that Drosophila telomere structure is epigenetically regulated by the histone deacetylase Rpd3.
Our study suggests a specific function for the general chromatin remodeling factor (show ASH1L ELISA Kits) Rpd3 in regulating dendrite targeting in neurons, largely through the postmitotic action of the Pros transcription factor.
The SIN3/RPD3 deacetylase complex is essential for G(2) phase cell cycle progression and regulation of SMRTER corepressor levels.
these results suggest that HDAC1 and HDAC6 may play a role in clear cell renal cell carcinoma biology
Histone deacetylase 1 regulates the expression of progesterone receptor (show PGR ELISA Kits) A during human parturition by occupying the progesterone receptor (show PGR ELISA Kits) A promoter.
High HDAC1 expression may contribute to the aggressiveness of human breast cancer with cytoplasmic-only expression of maspin (show SERPINB5 ELISA Kits)
Results indicate that HCV core induced epithelial-mesenchymal transition (EMT (show ITK ELISA Kits)) by interacting with the transcriptional repressor complex Snail (show SNAI1 ELISA Kits)/HDAC1/2 at the E-cadherin (show CDH1 ELISA Kits) promoter, which led to E-cadherin (show CDH1 ELISA Kits) repression and increased invasiveness of hepatoma cells.
Coexpression of SALL4 with HDAC1 and/or HDAC2 was associated with PTEN underexpression and a poor prognosis in hepatocellular carcinoma.
Meta-analysis results suggest that HDAC1 mRNA or protein expression may serve as a good diagnostic and prognostic marker for lung cancer.
Histone deacetylase assays confirmed that MIER2, but not MIER3 complexes, have associated deacetylase activity.
High HDAC1 expression is associated with drug Resistance in Malignant Melanoma.
HDAC1 overexpression is associated with Breast Cancer.
The effect of p53 (show TP53 ELISA Kits) expression on the development of cloned embryos, and its interaction with HDAC1 and DNMT3A (show DNMT3A ELISA Kits) are reported.
The results suggest that HDAC1 knock-down in oocytes did not influence the rates of maturation or cleavage of parthenogenetic embryos.
results indicate that HDAC1 plays an important role in otic vesicle formation.
HDAC (show HDAC3 ELISA Kits) activity is necessary for control of cell proliferation and migration of posterior lateral line primordium and hair cell differentiation during early stages of its development in zebrafish.
This study reveals distinct functional and temporal requirements for zebrafish hdac1 during neural crest-derived craniofacial and peripheral neuron development.
Hdac1 is required for expression of erm and fgf20a in rhombomeres; Hdac1-dependent expression of these two genes is attenuated in rhombomere boundary regions by Notch (show NOTCH1 ELISA Kits) signalling activity
HDAC1 is required for pancreatic epithelial proliferation in development and cancer.
Data indicate a novel role for Hdac1 as a positive regulator of gene transcription during development of the vertebrate CNS.
Findings suggest that Mta3 (show MTA1 ELISA Kits)-NuRD complex, inclding component HDAC1, is essential for the initiation of primitive hematopoiesis.
hdac1 is an essential component of the transcriptional silencing machinery that supports the formation and subsequent differentiation of neuronal precursors.
hdac1 is required for the normal formation of craniofacial cartilage and pectoral fins.
in vivo role of HDAC1 in regulating cell cycle progression is region-specific, as HDAC1 promotes cell cycle exit in the retina
Data show that proto-oncogene transcription factor Ets1 regulates neural crest development through histone deacetylase 1 HDAC1) to down-regulate bone morphogenetic protein (BMP) signaling output and reduce id3 protein expression.
Specific knockdown of HDAC1 by a morpholino (HDAC1-MO) decreased the number of BrdU- and BLBP-labeled cells and increased the acetylation level of histone H4 at lysine 12.
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
, histone deacetylase 1
, histone deacetylase 1-B
, Rpd3 histone deacetylase
, histone Deacetylase-1
, histone deacetylase
, histone deacetylase 1 (HDAC1)
, reduced potassium dependency 3
, suppressor of variegation 326
, reduced potassium dependency, yeast homolog-like 1
, histone deacetylase 1 b