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Browse our anti-Histone Deacetylase 2 (HDAC2) Antibodies

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anti-Histone Deacetylase 2 Antibodies (HDAC2)
On are 247 Histone Deacetylase 2 (HDAC2) Antibodies from 34 different suppliers available. Additionally we are shipping Histone Deacetylase 2 Kits (41) and Histone Deacetylase 2 Proteins (8) and many more products for this protein. A total of 312 Histone Deacetylase 2 products are currently listed.
D10Wsu179e, HD2, HISTONE DEACETYLASE, histone deacetylase 2, mRPD3, RPD3, T1N24.9, T1N24_9, YAF1, Yy1bp
list all antibodies Gene Name GeneID UniProt
HDAC2 3066 Q92769
HDAC2 15182 P70288
HDAC2 84577  

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Top referenced anti-Histone Deacetylase 2 Antibodies

  1. Chicken Polyclonal HDAC2 Primary Antibody for ICC, WB - ABIN223296 : Mao, Hou, Cao, Wang, Li, Chen, Fei, Hurren, Gronda, Wu, Trudel, Schimmer: The tricyclic antidepressant amitriptyline inhibits D-cyclin transactivation and induces myeloma cell apoptosis by inhibiting histone deacetylases: in vitro and in silico evidence. in Molecular pharmacology 2011 (PubMed)
    Show all 3 references for ABIN223296

  2. Human Polyclonal HDAC2 Primary Antibody for FACS, IF - ABIN653718 : Ishikawa, Miyoshi, Nose, Shibanuma: Transcriptional induction of MMP-10 by TGF-beta, mediated by activation of MEF2A and downregulation of class IIa HDACs. in Oncogene 2010 (PubMed)
    Show all 3 references for ABIN653718

  3. Human Polyclonal HDAC2 Primary Antibody for EIA, FACS - ABIN952698 : Bush, McKinsey: Protein acetylation in the cardiorenal axis: the promise of histone deacetylase inhibitors. in Circulation research 2010 (PubMed)
    Show all 3 references for ABIN952698

  4. Human Polyclonal HDAC2 Primary Antibody for IF, IHC (p) - ABIN197336 : Tsai, Seto: Regulation of histone deacetylase 2 by protein kinase CK2. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN197336

  5. Human Polyclonal HDAC2 Primary Antibody for ELISA, WB - ABIN1531855 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1531855

  6. Human Monoclonal HDAC2 Primary Antibody for ICC, IF - ABIN2668730 : Nayak, Glöckner-Pagel, Vaeth, Schumann, Buttmann, Bopp, Schmitt, Serfling, Berberich-Siebelt: Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. in The Journal of biological chemistry 2009 (PubMed)

  7. Cow (Bovine) Polyclonal HDAC2 Primary Antibody for ChIP, IHC - ABIN2777505 : Weichert, Röske, Niesporek, Noske, Buckendahl, Dietel, Gekeler, Boehm, Beckers, Denkert: Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)

  8. Cow (Bovine) Polyclonal HDAC2 Primary Antibody for IHC, WB - ABIN2779752 : Choi, Ko, Shin: The transcriptional corepressor, PELP1, recruits HDAC2 and masks histones using two separate domains. in The Journal of biological chemistry 2004 (PubMed)

  9. Mouse (Murine) Monoclonal HDAC2 Primary Antibody for ChIP, ICC - ABIN1042602 : Zupkovitz, Tischler, Posch, Sadzak, Ramsauer, Egger, Grausenburger, Schweifer, Chiocca, Decker, Seiser: Negative and positive regulation of gene expression by mouse histone deacetylase 1. in Molecular and cellular biology 2006 (PubMed)

More Antibodies against Histone Deacetylase 2 Interaction Partners

Human Histone Deacetylase 2 (HDAC2) interaction partners

  1. the current findings implicate the HDAC2/miR (show MLXIP Antibodies)-101/AMPK (show PRKAA1 Antibodies) pathway as a critical mediator of AD pathogenesis. These studies also highlight the importance of epigenetics in AD and provide novel therapeutic targets.

  2. Increased cancer-specific mortality was significantly associated with HDAC2 expression, mortality was also increased with high HDAC1 (show HDAC1 Antibodies) expression.

  3. HDAC2 upregulation is associated with hepatocellular carcinoma.

  4. Suggest that HDAC2 can trigger migration and invasion of non-small cell lung carcinoma cells by activating NF-kappaB (show NFKB1 Antibodies) to up-regulate fibronectin (show FN1 Antibodies) expression.

  5. KLF4 (show KLF4 Antibodies) acts as a tumor suppressor or oncogene (show RAB1A Antibodies) to activate or repress target gene transcription depending on its acetylation status, which is regulated by p21 (show CDKN1A Antibodies) and CK2 (show CSNK2A1 Antibodies) interaction-mediated HDAC2 phosphorylation

  6. Data indicate that bombesin receptor (show GRPR Antibodies)-activated protein (BRAP (show BRAP Antibodies)) might increase histone deacetylases 1/2 (HDAC (show HDAC3 Antibodies)) activity that leads to NF-kappa B (NF-kappaB (show NFKB1 Antibodies)) activation via its putative C-terminal domain.

  7. Decreased HDAC2 expression is associated with cisplatin resistance in ovarian cancer.

  8. In cigarette smoke extract-exposed airway epithelial cells and macrophages, HDAC2 is excessively ubiquitinated and degraded in the proteasome attributed to low expression of USP17.

  9. The results imply that HDAC2 is involved in the transcriptional regulation of human odontoblasts in vivo.

  10. Endothelial-Mesenchymal Transition is initiated by recruitment of aberrantly phosphorylated DNMT1 (show DNMT1 Antibodies) to the RASAL1 (show RASAL1 Antibodies) CpG island promoter by HDAC2, causing aberrant promoter methylation and transcriptional suppression.

Mouse (Murine) Histone Deacetylase 2 (HDAC2) interaction partners

  1. observations suggest that Methamphetamine may induce large-scale transcriptional changes in the Nuc (show SREBF2 Antibodies). Accumbens by regulating the expression of several histone deacetylases in part, via HDAC2-dependent mechanisms.

  2. We also found that glucocorticoid receptor (GR (show NR3C1 Antibodies))-mediated histone deacetylase 2 (HDAC) 2 expression and activity are reduced in the Trpv1 (show TRPV1 Antibodies)(-/-) mice and that HDAC2-regulated, cell-cycle- and neuroplasticity-related molecules are altered

  3. CRISPR/Cas9-mediated disruption of the Hdac2 gene increased Slc2a1 expression, suggesting that it is one of the responsible histone deacetylases (HDACs). These results confirm that b-OHB is a HDAC inhibitor and show that b-OHB plays an important role in fasting-induced epigenetic activation of a glucose transporter gene in the brain.

  4. Data suggest that pathological cardiac hypertrophy involved class I histone deacetylases HDAC1 (show HDAC1 Antibodies) and HdAC2, tuberous sclerosis complex 2 (TSC2 (show TSC2 Antibodies)), and mTOR (show FRAP1 Antibodies) srine-threonine kinases (mTOR (show FRAP1 Antibodies)).

  5. Social isolation resulted in down-regulation of Hdac2 mRNA expression in the cerebral cortex.

  6. HDAC2 may regulate the expression of immediate early (show JUN Antibodies) genes, in part, by prolonging the actions of pCREB in the mouse nucleus accumbens.

  7. Injecting these oocytes with Hdac2 partially restores DNMT3A2 (show DNMT3A Antibodies) nuclear staining.

  8. Our data show that: i) HDAC2 levels and activity are increased in NPC (show NPC1 Antibodies) neuronal models and in Npc1 (show NPC1 Antibodies)(-/-) mice; ii) inhibition of c-Abl (show ABL1 Antibodies) or c-Abl (show ABL1 Antibodies) deficiency prevents the increase of HDAC2 protein levels and activity in NPC (show NPC1 Antibodies) neuronal models

  9. This study reveals a dominant negative effect of catalytically inactive HDAC2 on specific corepressor complexes resulting in histone hyperacetylation, transcriptional derepression, and, ultimately, perinatal lethality.

  10. This study demonstrated that hdac2 increase in skeletal muscle in muscle atrophy.

Histone Deacetylase 2 (HDAC2) Antigen Profile

Antigen Summary

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Histone Deacetylase 2 (HDAC2)

  • histone deacetylase 2 (HDAC2) antibody
  • histone deacetylase 2 (Hdac2) antibody
  • histone deacetylase 2 (hdac2) antibody
  • histone deacetylase 2 (HDA2) antibody
  • histone deacetylase 2-like (LOC100156170) antibody
  • D10Wsu179e antibody
  • HD2 antibody
  • histone deacetylase 2 antibody
  • mRPD3 antibody
  • RPD3 antibody
  • T1N24.9 antibody
  • T1N24_9 antibody
  • YAF1 antibody
  • Yy1bp antibody

Protein level used designations for HDAC2

YY1-associated factor 1 , transcriptional regulator homolog RPD3 , HD2 , YY1 transcription factor-binding protein , histone deacetylase-2

3066 Homo sapiens
475035 Canis lupus familiaris
15182 Mus musculus
84577 Rattus norvegicus
407223 Bos taurus
395635 Gallus gallus
399252 Xenopus laevis
100715675 Cavia porcellus
101107708 Ovis aries
832673 Arabidopsis thaliana
100156170 Sus scrofa
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