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our data showed that Apr-1 plays a crucial role in cell proliferation by controlling cell cycle progression, implying a tumor-suppressor function of Apr-1 in cholangiocarcinoma carcinogenesis
Data indicate that the neonatal detection test sensitivity obtained was 95% with a positive predictive value of 1 in the analyses for both the arylsulfatase E (ARSE (show ARSE Proteins)) and melanoma antigen family H1 (MAGEH1) genes.
The induction of APR-1 expression caused apoptosis of melanoma cells via the interaction with the juxtamembrane region of p75 neurotrophin receptor (show NGFR Proteins).
This gene is thought to be involved in apoptosis. Multiple polyadenylation sites have been found for this gene.
melanoma antigen family H, 1
, apoptosis-related protein 1
, melanoma-associated antigen H1
, MAGE-H1 antigen