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Browse our Myocyte Enhancer Factor 2A Proteins (MEF2A)

Full name:
Myocyte Enhancer Factor 2A Proteins (MEF2A)
On www.antibodies-online.com are 11 Myocyte Enhancer Factor 2A (MEF2A) Proteins from 5 different suppliers available. Additionally we are shipping Myocyte Enhancer Factor 2A Antibodies (245) and Myocyte Enhancer Factor 2A Kits (18) and many more products for this protein. A total of 289 Myocyte Enhancer Factor 2A products are currently listed.
Synonyms:
A430079H05Rik, adcad1, mef2, mef2a, rsrfc4, rsrfc9, sl2, wu:fd19d02, xmef2a
list all proteins Gene Name GeneID UniProt
MEF2A 4205 Q02078
MEF2A 17258 Q60929
MEF2A 309957 Q2MJT0

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Myocyte Enhancer Factor 2A Proteins (MEF2A) by Origin

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Trematode (Schistosoma mansoni) Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. Using a dominant-negative SmMef2 mutant, authors provide evidence that SmMef2 may regulate genes in the WNT (show WNT2 Proteins) pathway.

  2. The authors identify and characterize Mef2 (show MYEF2 Proteins) from the schistosome worm Schistosoma mansoni (SmMef2).

Human Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. The findings of this study are consistent with MEF2A deregulation conferring risk of formal thought disorder.

  2. Variants in the 3'-UTR of MEF2A are associated with coronary artery disease in a Chinese Han population.

  3. p38 MAPK (show MAPK14 Proteins) is a key regulator of canonical Wnt (show WNT2 Proteins) signaling by promoting a phospho-dependent interaction between MEF2 and beta-catenin (show CTNNB1 Proteins) to enhance cooperative transcriptional activity and cell proliferation.

  4. Mechanistically, MEF-2 (show MYEF2 Proteins) was recruited to the viral promoter (LTR, long terminal repeat) in the context of chromatin, and constituted Tax (show CNTN2 Proteins)/CREB (show CREB1 Proteins) transcriptional complex via direct binding to the HTLV-1 LTR.

  5. Our results revealed a link and interaction between MEF2A and miR (show MLXIP Proteins)-143 and suggested a potential mechanism for MEF2A to regulate H(2)O(2) -induced VSMC senescence.

  6. six or seven amino acid deletions and synonymous mutations (147143G-->A)in exon 11 of the MEF2A gene may be correlated with susceptibility to coronary artery disease in the Chinese population

  7. MEF2A is targeted to lysosomes for chaperone-mediated autophagy degradation; oxidative stress-induced (show SQSTM1 Proteins) lysosome destabilization leads to the disruption of MEF2A degradation as well as the dysregulation of its function

  8. MEF2 transcription factors promotes epithelial-mesenchymal transition and invasiveness of hepatocellular carcinoma through TGF-beta1 (show TGFB1 Proteins) autoregulation circuitry.

  9. MEF2 is the key cis (show CISH Proteins)-acting factor that regulates expression of a number of transcriptional targets involved in pulmonary vascular homeostasis, including microRNAs 424 and 503, connexins 37, and 40, and Kruppel Like Factors 2 and 4.

  10. SENP2 (show SUMO1 Proteins) plays an important role in determining the dynamics and functional outcome of MEF2A SUMOylation and transcriptional activation.

Mouse (Murine) Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. Knockdown of MEF2A significantly reduced hyperglycemia-induced cardiac fibroblast proliferation and migration, myofibroblast differentiation, matrix metalloproteinase (show MMP20 Proteins) activities, and collagen production.

  2. Lentivirus-mediated MEF 2A shRNA accelerates inflammation and atherosclerosis in APOE (show APOE Proteins) knockout mice, but has no effect on lipoprotein levels in plasma.

  3. microRNAs encoded by the Gtl2-Dio3 (show DIO3 Proteins) noncoding RNA locus function downstream of the MEF2A

  4. Our results indicated that exercise-induced CPT1b (show CPT1B Proteins) expression was at least in part mediated by HDAC5 (show HDAC5 Proteins)/MEF2A interaction.

  5. MEF2A is targeted to lysosomes for chaperone-mediated autophagy degradation; oxidative stress-induced (show SQSTM1 Proteins) lysosome destabilization leads to the disruption of MEF2A degradation as well as the dysregulation of its function

  6. Whereas MEF2A is absolutely required for proper myoblast differentiation, MEF2B (show MEF2B Proteins), -C, and -D were found to be dispensable for this process.

  7. A role for endogenous MEF2 (show MEF2C Proteins) factors exclusively in hormone/Fsk/cAMP-induced Nr4a1 (show NR4A1 Proteins) gene expression in mouse MA-10 Leydig cells.

  8. Combined deletion of the Mef2a, c, and d genes results in a blockade to muscle regeneration.

  9. Cross-talk between p38MAPK (show MAPK14 Proteins) and GSK3beta signaling converges on MEF2 (show MEF2C Proteins) activity.

  10. Myocyte enhancer factor 2A (MEF2A) controls skeletal muscle regeneration in adult mice through direct regulation of the largest known mammalian microRNA (miRNA) cluster, the Gtl2-Dio3 (show DIO3 Proteins) locus.

Xenopus laevis Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. These results show that NLK specifically regulates the MEF2A activity required for anterior formation in Xenopus development.

Cow (Bovine) Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. polymorphisms in the bovine MEF2A gene and their effect on the MEF2A mRNA expression level in the longissimus dorsi muscle

Zebrafish Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. Results suggest that myocyte-specific enhancer factor 2A is essential for cardiac contractility

  2. Results suggest that myocyte enhancer factor 2A is essential for zebrafish posterior somite development.

Myocyte Enhancer Factor 2A (MEF2A) Protein Profile

Protein Summary

The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Myocyte Enhancer Factor 2A (MEF2A)

  • myocyte enhancer factor 2A (MEF2A)
  • myocyte-specific enhancer factor 2A (EDI_092490)
  • myocyte-specific enhancer factor 2A (EDI_038250)
  • myocyte-specific enhancer factor 2a (Smp_161530)
  • myocyte-specific enhancer factor 2a (Smp_129430)
  • myocyte enhancer factor 2A (mef2a)
  • myocyte enhancer factor 2A (Mef2a)
  • myocyte enhancer factor 2a (Mef2a)
  • myocyte enhancer factor 2aa (mef2aa)
  • A430079H05Rik protein
  • adcad1 protein
  • mef2 protein
  • mef2a protein
  • rsrfc4 protein
  • rsrfc9 protein
  • sl2 protein
  • wu:fd19d02 protein
  • xmef2a protein

Protein level used designations for MEF2A

myocyte-specific enhancer factor 2A , myocyte-specific enhancer factor 2a , myocyte enhancer factor 2A , MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) , myocyte-specific enhancer factor 2A-like , myocyte-specific enhancer factor 2A homolog , serum response factor-like protein 1 , SL-2 , XMEF2A1 , serum response factor-like protein 2 , xMEF2A , etID309779.18 , myocyte enhancer factor 2a

GENE ID SPECIES
100050068 Equus caballus
5881199 Entamoeba dispar SAW760
5883634 Entamoeba dispar SAW760
8341405 Schistosoma mansoni
8345426 Schistosoma mansoni
100171617 Pongo abelii
453680 Pan troglodytes
708956 Macaca mulatta
100216045 Xenopus (Silurana) tropicalis
100399429 Callithrix jacchus
100555625 Anolis carolinensis
100589007 Nomascus leucogenys
4205 Homo sapiens
17258 Mus musculus
309957 Rattus norvegicus
395670 Gallus gallus
479021 Canis lupus familiaris
100037273 Sus scrofa
100339777 Oryctolagus cuniculus
380452 Xenopus laevis
407231 Bos taurus
30564 Danio rerio
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