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Browse our anti-PCSK5 (PCSK5) Antibodies

Full name:
anti-Proprotein Convertase Subtilisin/kexin Type 5 Antibodies (PCSK5)
On www.antibodies-online.com are 44 Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5) Antibodies from 11 different suppliers available. Additionally we are shipping PCSK5 Proteins (5) and PCSK5 Kits (3) and many more products for this protein. A total of 58 PCSK5 products are currently listed.
Synonyms:
b2b585Clo, b2b1549Clo, fur2, MGC98915, Pc5, PC5/6A, PC5A, pc6, PC6A, PCSK5, SPC6, spc6a, subtilase
list all antibodies Gene Name GeneID UniProt
PCSK5 18552 Q04592
PCSK5 116548 P41413
PCSK5 5125 Q92824

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Most Popular Reactivities for anti-PCSK5 (PCSK5) Antibodies

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anti-Mouse (Murine) PCSK5 Antibodies:

anti-Rat (Rattus) PCSK5 Antibodies:

anti-Human PCSK5 Antibodies:

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Top referenced anti-PCSK5 Antibodies

  1. Human Polyclonal PCSK5 Primary Antibody for WB - ABIN1881639 : Heng, Paule, Hardman, Li, Singh, Rainczuk, Stephens, Nie: Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment. in Endocrinology 2010 (PubMed)
    Show all 3 references for ABIN1881639

  2. Human Polyclonal PCSK5 Primary Antibody for WB - ABIN2781306 : Szumska, Pieles, Essalmani, Bilski, Mesnard, Kaur, Franklyn, El Omari, Jefferis, Bentham, Taylor, Schneider, Arnold, Johnson, Tymowska-Lalanne, Stammers, Clarke, Neubauer, Morris, Brown, Shaw-Smith, Cama, Capra, Ragoussis, Constam, Seidah, Prat, Bhattacha: VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5. in Genes & development 2008 (PubMed)

More Antibodies against PCSK5 Interaction Partners

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5) interaction partners

  1. overexpression of PCs, furin (show FURIN Antibodies) and PC5, but not PC7 (show PCSK7 Antibodies), which are all expressed in SMC (show DYM Antibodies), increase PKGI (show PRKG1 Antibodies) cleavage in a dose-dependent manner

  2. Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy.

  3. PCSK5 and GDF11 (show GDF11 Antibodies) expression during hindgut morphogenesis could be key factors for normal anorectal development, which can be disturbed by the administration of an overdose of all-trans retinoic acid, leading to anorectal malformations.

  4. Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.

  5. These data support the role of proconvertase PCSK5 in the processing of ovarian inhibin subunits during folliculogenesis.

  6. Data suggest that intestinal PC5/6 is protective towards tumorigenesis, especially in mouse duodenum, and possibly in human colon.

  7. The proprotein convertase PC5A and a metalloprotease (show ADAMTS7 Antibodies) are involved in the proteolytic processing of the neural adhesion molecule (show CNTN6 Antibodies) L1.

  8. large cysteine-rich region acts as an important part of functional domain of PC6

  9. PC6 is an essential molecule in modulating uterine function to support the establishment of embryo implantation

  10. the CRD (show CRX Antibodies) of PC5A and PACE4 (show PCSK6 Antibodies) functions as a cell surface anchor favoring the processing of their cognate surface-anchored substrates, including endothelial lipase (show LIPG Antibodies)

Human Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5) interaction partners

  1. Case Report: whole exome sequencing of a case with the VACTERL association uncovered a novel frameshift mutation in the PCSK5 gene.

  2. full-length alpha-DG in the human endometrial epithelium is a barrier for embryo attachment and that removal of alpha-DG-N by proprotein convertase 5/6 (PC6; a protease critical for implantation

  3. Proprotein convertase 5/6 cleaves PDGFA (show PDGFA Antibodies) in the human endometrium in preparation for embryo implantation.

  4. PC5/6A is involved in squamous differentiation of human nasal epithelial cells, possibly through up-regulation of the BMP-2 (show BMP2 Antibodies) signaling pathway.

  5. overexpression of PCs, furin (show FURIN Antibodies) and PC5, but not PC7 (show PCSK7 Antibodies), which are all expressed in SMC (show DYM Antibodies), increase PKGI (show PRKG1 Antibodies) cleavage in a dose-dependent manner

  6. study implicates PC6 as a key regulatory protein essential for the attachment of the blastocyst to the endometrial epithelium through the processing of pro-integrin-alphas

  7. PC6 plays a key role in regulating fundamental cellular remodeling processes, such as plasma membrane transformation and membrane-cytoskeletal interface reorganization.

  8. Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.

  9. PC6 may have a role in uterine receptivity and its uterine lavage levels appear to be significantly lower in a subgroup of women with unexplained infertility

  10. PTPkappa was scissored by the processed form of proprotein convertase 5, and galectin-3 binding protein (show LGALS3BP Antibodies) which is over-produced in colon cancer cells and tissues.

PCSK5 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PCSK5

  • proprotein convertase subtilisin/kexin type 5 (PCSK5) antibody
  • proprotein convertase subtilisin/kexin type 5 (pcsk5) antibody
  • proprotein convertase subtilisin/kexin type 5 (Pcsk5) antibody
  • b2b585Clo antibody
  • b2b1549Clo antibody
  • fur2 antibody
  • MGC98915 antibody
  • Pc5 antibody
  • PC5/6A antibody
  • PC5A antibody
  • pc6 antibody
  • PC6A antibody
  • PCSK5 antibody
  • SPC6 antibody
  • spc6a antibody
  • subtilase antibody

Protein level used designations for PCSK5

proprotein convertase subtilisin/kexin type 5 , proprotein convertase PC6 , proprotein convertase 6A , proprotein convertase 6B , proprotein convertase 6C , proprotein convertase 6D , proprotein convertase 6E , proprotein convertase 6F , subtilisin-like protease SPC6A , proprotein convertase 5 , proprotein convertase 6 , proprotein convertase PC5 , subtilisin-like proprotein convertase 6 , subtilisin/kexin-like protease PC5 , hPC6 , prohormone convertase 5 , protease PC6

GENE ID SPECIES
395456 Gallus gallus
446297 Xenopus laevis
464533 Pan troglodytes
484160 Canis lupus familiaris
528098 Bos taurus
779961 Xenopus (Silurana) tropicalis
100589851 Nomascus leucogenys
18552 Mus musculus
116548 Rattus norvegicus
5125 Homo sapiens
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