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Browse our anti-PLEKHG5 (PLEKHG5) Antibodies

Full name:
anti-Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 Antibodies (PLEKHG5)
On www.antibodies-online.com are 40 Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5) Antibodies from 10 different suppliers available. Additionally we are shipping PLEKHG5 Proteins (3) and many more products for this protein. A total of 44 PLEKHG5 products are currently listed.
Synonyms:
BC023181, DSMA4, GEF720, mKIAA0720, plekhg5, si:ch211-15p9.7, Syx, syx-a, Tech
list all antibodies Gene Name GeneID UniProt
PLEKHG5 57449 O94827
PLEKHG5 269608 Q66T02
PLEKHG5 310999 Q6RFZ7

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Most Popular Reactivities for anti-PLEKHG5 (PLEKHG5) Antibodies

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anti-Human PLEKHG5 Antibodies:

anti-Mouse (Murine) PLEKHG5 Antibodies:

anti-Rat (Rattus) PLEKHG5 Antibodies:

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Top referenced anti-PLEKHG5 Antibodies

  1. Human Monoclonal PLEKHG5 Primary Antibody for IF, IHC (p) - ABIN566110 : Ngok, Geyer, Liu, Kourtidis, Agrawal, Wu, Seerapu, Lewis-Tuffin, Moodie, Huveldt, Marx, Baraban, Storz, Horowitz, Anastasiadis: VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. in The Journal of cell biology 2012 (PubMed)
    Show all 2 references for ABIN566110

  2. Human Polyclonal PLEKHG5 Primary Antibody for EIA, IHC (fro) - ABIN1108670 : Maystadt, Rezsöhazy, Barkats, Duque, Vannuffel, Remacle, Lambert, Najimi, Sokal, Munnich, Viollet, Verellen-Dumoulin: The nuclear factor kappaB-activator gene PLEKHG5 is mutated in a form of autosomal recessive lower motor neuron disease with childhood onset. in American journal of human genetics 2007 (PubMed)

More Antibodies against PLEKHG5 Interaction Partners

Human Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5) interaction partners

  1. Results indicate that different mutations in PLEKHG5 lead to clinically diverse outcomes Charcot-Marie-Tooth disease or lower motor neuron disease affecting the function of neurons and glial cells.

  2. Recruitment of Syx to the cell membrane, the selective activation of Dia1 signaling, coupled with the suppression of ROCK and actin reorganization, plays a key role in establishing cell polarity during directed cell migration.

  3. This study identifies compound heterozygous PLEKHG5 mutations as the cause of recessive intermediate Charcot-Marie-Tooth disease.

  4. a novel means of regulating junctional Syx localization and function by phosphorylation-induced 14-3-3 (show YWHAQ Antibodies) binding and further support the importance of Syx function in maintaining stable cell-cell contacts.

  5. We identified a homozygous missense mutation (c.1940 T-->C [p.647 Phe-->Ser (show SIGLEC1 Antibodies)]) of the Pleckstrin (show PLEK Antibodies) homology domain-containing, family G member 5 gene (show GPD1 Antibodies), PLEKHG5, in families with lower motor neuron disease.

Mouse (Murine) Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5) interaction partners

  1. Results indicate that different mutations in PLEKHG5 lead to clinically diverse outcomes Charcot-Marie-Tooth disease or lower motor neuron disease affecting the function of neurons and glial cells.

  2. a novel means of regulating junctional Syx localization and function by phosphorylation-induced 14-3-3 (show YWHAQ Antibodies) binding and further support the importance of Syx function in maintaining stable cell-cell contacts.

  3. VEGF (show VEGFA Antibodies) causes translocation of Syx from cell junctions, promoting junction disassembly, whereas angiopoietin 1 (show ANGPT1 Antibodies) maintains Syx at the junctions, inducing junction stabilization.

  4. a well defined Rnd3 (show RND3 Antibodies) effector Syx

PLEKHG5 Antigen Profile

Antigen Summary

This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PLEKHG5

  • pleckstrin homology domain containing, family G (with RhoGef domain) member 5 (PLEKHG5) antibody
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 5a (plekhg5a) antibody
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 5 (plekhg5) antibody
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 5 (Plekhg5) antibody
  • BC023181 antibody
  • DSMA4 antibody
  • GEF720 antibody
  • mKIAA0720 antibody
  • plekhg5 antibody
  • si:ch211-15p9.7 antibody
  • Syx antibody
  • syx-a antibody
  • Tech antibody

Protein level used designations for PLEKHG5

pleckstrin homology domain containing, family G (with RhoGef domain) member 5 , pleckstrin homology domain containing family G member 5 , pleckstrin homology domain-containing family G member 5-like , NFkB activating protein , PH domain-containing family G member 5 , guanine nucleotide exchange factor 720 , novel PH domain-containing protein , pleckstrin homology domain-containing family G member 5 , synectin-binding guanine exchange factor , RhoA-specific guanine exchange factor SYX1 , RhoA-specific guanine exchange factor SYX2 , synectin-binding RhoA exchange factor , neuronal RhoA GEF protein , transcript highly enriched in cortex and hippocampus

GENE ID SPECIES
426013 Gallus gallus
479590 Canis lupus familiaris
562861 Danio rerio
615910 Bos taurus
703518 Macaca mulatta
100026753 Monodelphis domestica
100059388 Equus caballus
100350922 Oryctolagus cuniculus
100391235 Callithrix jacchus
100472277 Ailuropoda melanoleuca
100496612 Xenopus (Silurana) tropicalis
100516377 Sus scrofa
100583767 Nomascus leucogenys
57449 Homo sapiens
269608 Mus musculus
310999 Rattus norvegicus
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