You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our PLEKHG5 Proteins (PLEKHG5)

Full name:
Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 Proteins (PLEKHG5)
On www.antibodies-online.com are 3 Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5) Proteins from 2 different suppliers available. Additionally we are shipping PLEKHG5 Antibodies (39) and many more products for this protein. A total of 43 PLEKHG5 products are currently listed.
Synonyms:
BC023181, DSMA4, GEF720, mKIAA0720, plekhg5, si:ch211-15p9.7, Syx, syx-a, Tech
list all proteins Gene Name GeneID UniProt
PLEKHG5 57449 O94827
PLEKHG5 269608 Q66T02
Rat PLEKHG5 PLEKHG5 310999 Q6RFZ7

Show all synonyms

PLEKHG5 Proteins (PLEKHG5) by Origin

Select your origin of interest

More Proteins for PLEKHG5 Interaction Partners

Human Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5) interaction partners

  1. Results indicate that different mutations in PLEKHG5 lead to clinically diverse outcomes Charcot-Marie-Tooth disease or lower motor neuron disease affecting the function of neurons and glial cells.

  2. Recruitment of Syx to the cell membrane, the selective activation of Dia1 signaling, coupled with the suppression of ROCK and actin reorganization, plays a key role in establishing cell polarity during directed cell migration.

  3. This study identifies compound heterozygous PLEKHG5 mutations as the cause of recessive intermediate Charcot-Marie-Tooth disease.

  4. a novel means of regulating junctional Syx localization and function by phosphorylation-induced 14-3-3 (show YWHAQ Proteins) binding and further support the importance of Syx function in maintaining stable cell-cell contacts.

  5. We identified a homozygous missense mutation (c.1940 T-->C [p.647 Phe-->Ser (show SIGLEC1 Proteins)]) of the Pleckstrin (show PLEK Proteins) homology domain-containing, family G member 5 gene (show GPD1 Proteins), PLEKHG5, in families with lower motor neuron disease.

Mouse (Murine) Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5) interaction partners

  1. Results indicate that different mutations in PLEKHG5 lead to clinically diverse outcomes Charcot-Marie-Tooth disease or lower motor neuron disease affecting the function of neurons and glial cells.

  2. a novel means of regulating junctional Syx localization and function by phosphorylation-induced 14-3-3 (show YWHAQ Proteins) binding and further support the importance of Syx function in maintaining stable cell-cell contacts.

  3. VEGF (show VEGFA Proteins) causes translocation of Syx from cell junctions, promoting junction disassembly, whereas angiopoietin 1 (show ANGPT1 Proteins) maintains Syx at the junctions, inducing junction stabilization.

  4. a well defined Rnd3 (show RND3 Proteins) effector Syx

PLEKHG5 Protein Profile

Protein Summary

This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PLEKHG5

  • pleckstrin homology domain containing, family G (with RhoGef domain) member 5 (PLEKHG5)
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 5a (plekhg5a)
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 5 (plekhg5)
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 5 (Plekhg5)
  • BC023181 protein
  • DSMA4 protein
  • GEF720 protein
  • mKIAA0720 protein
  • plekhg5 protein
  • si:ch211-15p9.7 protein
  • Syx protein
  • syx-a protein
  • Tech protein

Protein level used designations for PLEKHG5

pleckstrin homology domain containing, family G (with RhoGef domain) member 5 , pleckstrin homology domain containing family G member 5 , pleckstrin homology domain-containing family G member 5-like , NFkB activating protein , PH domain-containing family G member 5 , guanine nucleotide exchange factor 720 , novel PH domain-containing protein , pleckstrin homology domain-containing family G member 5 , synectin-binding guanine exchange factor , RhoA-specific guanine exchange factor SYX1 , RhoA-specific guanine exchange factor SYX2 , synectin-binding RhoA exchange factor , neuronal RhoA GEF protein , transcript highly enriched in cortex and hippocampus

GENE ID SPECIES
426013 Gallus gallus
479590 Canis lupus familiaris
562861 Danio rerio
615910 Bos taurus
703518 Macaca mulatta
100026753 Monodelphis domestica
100059388 Equus caballus
100350922 Oryctolagus cuniculus
100391235 Callithrix jacchus
100472277 Ailuropoda melanoleuca
100496612 Xenopus (Silurana) tropicalis
100516377 Sus scrofa
100583767 Nomascus leucogenys
57449 Homo sapiens
269608 Mus musculus
310999 Rattus norvegicus
Selected quality suppliers for PLEKHG5 Proteins (PLEKHG5)
Did you look for something else?