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Browse our RAP1A Proteins (RAP1A)

Full name:
RAP1A, Member of RAS Oncogene Family Proteins (RAP1A)
On www.antibodies-online.com are 10 RAP1A, Member of RAS Oncogene Family (RAP1A) Proteins from 6 different suppliers available. Additionally we are shipping RAP1A Antibodies (69) and RAP1A Kits (7) and many more products for this protein. A total of 91 RAP1A products are currently listed.
Synonyms:
AI848598, G-22K, Krev-1, KREV1, RAP-1A, Rap1, rap 1A, SMGP21, wu:fc66g06, zgc:86676
list all proteins Gene Name GeneID UniProt
RAP1A 5906 P62834
RAP1A 295347 P62836
RAP1A 109905 P62835

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RAP1A Proteins (RAP1A) by Origin

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Top referenced RAP1A Proteins

  1. Human RAP1A Protein expressed in Escherichia coli (E. coli) - ABIN667792 : Han, Colicelli: A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1. in Molecular and cellular biology 1995 (PubMed)
    Show all 2 references for ABIN667792

  2. Human RAP1A Protein expressed in Wheat germ - ABIN1317390 : Chu, Awasthi, White, Chrzanowska-Wodnicka, Malarkannan: Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 2 references for ABIN1317390

More Proteins for RAP1A Interaction Partners

Zebrafish RAP1A, Member of RAS Oncogene Family (RAP1A) interaction partners

  1. RAP1 (show TERF2IP Proteins)-mediated MEK (show MAP2K1 Proteins)/ERK (show MAPK1 Proteins) pathway defects in Kabuki syndrome.

Human RAP1A, Member of RAS Oncogene Family (RAP1A) interaction partners

  1. A receptor type-protein tyrosine phosphatase alpha-Src family kinase-Rap1 pathway was identified as responsible for recruiting myosin IIB to the zonula adherens in epithelial cells and supporting contractile tension.

  2. Rap1 (show RABGEF1 Proteins)- and Rac1-GTPase (show RACGAP1 Proteins) activation have roles in hypoxia/reoxygenation-experienced cancer cell migration and metastasis via the expression of thymosin beta-4 (show TMSB4X Proteins)

  3. These findings provide further evidence that a crucial role for miR (show MLXIP Proteins)-203 in inhibiting metastasis of PCa (show FLVCR1 Proteins) through the suppression of Rap1A expression.

  4. Our findings suggest that RAP1 (show RABGEF1 Proteins) may be a useful biomarker for the diagnosis of ical (show CAST Proteins) intraepithelial neoplasia .

  5. RAP1 (show RABGEF1 Proteins)-mediated MEK (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins) pathway defects in Kabuki syndrome.

  6. Rap1 knockdown attenuates prostacyclin (PC)-induced vascular endothelial cell (EC) monolayer recovery.

  7. Data indicate that through GTPase-activating proteins ArhGAP29 complex formation Rap1 GTP-binding protein spatially restricts Rho-mediated signaling, which is necessary for endothelial barrier potentiation.

  8. The direct interaction between Zscan4 (show ZSCAN4 Proteins) and Rap1 (show RABGEF1 Proteins) may explain how Zscan4 (show ZSCAN4 Proteins) rapidly increases telomere length, yielding important information about the role of these proteins in telomere biology.

  9. Phosphorylation of synaptic GTPase-activating protein (show RASA1 Proteins) (synGAP (show SYNGAP1 Proteins)) by Ca2+/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 5 (CDK5 (show CDK5 Proteins)) alters the ratio of its GAP activity toward Ras and Rap (show LRPAP1 Proteins) GTPases.

  10. crystal structure of an active, GTP (show AK3 Proteins)-bound GTPase (show RACGAP1 Proteins) domain of Rap1 (show RABGEF1 Proteins) in complex with the Ras association (RA)-pleckstrin (show PLEK Proteins) homology (PH) structural module of RIAM (show APBB1IP Proteins) at 1.65 A, is reported.

Cow (Bovine) RAP1A, Member of RAS Oncogene Family (RAP1A) interaction partners

  1. Rap1 (show TERF2IP Proteins) increases KRIT-1 (show KRIT1 Proteins) targeting to endothelial cell-cell junctions where it suppresses stress fibers and stabilizes junctional integrity.

Mouse (Murine) RAP1A, Member of RAS Oncogene Family (RAP1A) interaction partners

  1. These findings ascribe a new function to SLAT, and identify Rap1 as a target of SLAT function in TCR-mediated inside-out signaling.

  2. Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature

  3. Rap1 deficiency impaired T-cell homeostasis.

  4. Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function

  5. these data show that Treg degrade ATP to adenosine via CD39, attracting DC by activating Epac1-Rap1-dependent pathways.

  6. Phosphorylation of synaptic GTPase-activating protein (show RASA1 Proteins) (synGAP (show SYNGAP1 Proteins)) by Ca2+/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 5 (CDK5 (show CDK5 Proteins)) alters the ratio of its GAP activity toward Ras and Rap (show LRPAP1 Proteins) GTPases.

  7. Mex3b is involved in the spatial organization of the Rap1 pathway that orchestrates Sertoli cell functions.

  8. RASIP1 regulates the integrity of newly formed blood vessels as an effector of EPAC1-RAP1 signaling.

  9. PI3-kinase gamma (show PIK3CG Proteins) promotes Rap1a-mediated activation of myeloid cell integrin alpha4beta1, leading to tumor inflammation and growth.

  10. Rap1 has distinct patterns of signaling in normal vascular morphogenesis and dysfunction. (Review)

RAP1A Protein Profile

Protein Summary

The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

Alternative names and synonyms associated with RAP1A

  • RAP1A, member of RAS oncogene family (LOC100338584)
  • RAP1A, member of RAS oncogene family (LOC100351588)
  • RAP1A, member of RAS oncogene family (rap1a)
  • RAP1A, member of RAS oncogene family (RAP1A)
  • RAP1A, member of RAS oncogene family (Rap1a)
  • RAS-related protein-1a (Rap1a)
  • AI848598 protein
  • G-22K protein
  • Krev-1 protein
  • KREV1 protein
  • RAP-1A protein
  • Rap1 protein
  • rap 1A protein
  • SMGP21 protein
  • wu:fc66g06 protein
  • zgc:86676 protein

Protein level used designations for RAP1A

RAP1A, member of RAS oncogene family , Rap1b , ras-related protein Rap-1A , C21KG , G-22K , GTP-binding protein smg p21A , RAS-related protein RAP1A , Ras-related protein Krev-1 , RAS-related protein 1a , ras-related protein Krev-1 , GTP-binding protein smg-p21A , GTP-binding protein SMG-P21A

GENE ID SPECIES
100338584 Oryctolagus cuniculus
100351588 Oryctolagus cuniculus
415242 Danio rerio
779127 Xenopus laevis
419867 Gallus gallus
5906 Homo sapiens
101115080 Ovis aries
295347 Rattus norvegicus
282031 Bos taurus
109905 Mus musculus
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