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Browse our RAPGEF2 Proteins (RAPGEF2)

Full name:
Rap Guanine Nucleotide Exchange Factor (GEF) 2 Proteins (RAPGEF2)
On www.antibodies-online.com are 3 Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) Proteins from 2 different suppliers available. Additionally we are shipping RAPGEF2 Antibodies (24) and RAPGEF2 Kits (2) and many more products for this protein. A total of 31 RAPGEF2 products are currently listed.
Synonyms:
5830453M24Rik, CNRasGEF, fa11h07, MGC83978, mKIAA0313, nRap GEP, nRapGEP, PDZ-GEF1, Pdzgef1, RA-GEF, RA-GEF-1, Rap-GEP, RAPGEF2, wu:fa11h07
list all proteins Gene Name GeneID UniProt
RAPGEF2 9693 Q9Y4G8
RAPGEF2 76089  
Rat RAPGEF2 RAPGEF2 310533 F1M386

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RAPGEF2 Proteins (RAPGEF2) by Origin

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More Proteins for RAPGEF2 Interaction Partners

Zebrafish Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) interaction partners

  1. We report that in response to factors that promote cell motility, the Rap guanine exchange factor RAPGEF2 is rapidly phosphorylated by I-kappa-B-kinase-beta and casein kinase-1alpha and consequently degraded by the proteasome.

Cow (Bovine) Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) interaction partners

  1. Data indicate that Rapgef2 is a cAMP-binding protein present in chromaffin cells.

Human Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) interaction partners

  1. Cdk5 (show CDK5 Proteins)-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex.

  2. local accumulation of PDZGEF at the apical membrane during establishment of epithelial polarity is mediated by electrostatic interactions between positively charged side chains in the PDZ domain and negatively charged phosphatidic acid.

  3. SCF(FBXW11) bound, polyubiquitylated, and destabilized RAPGEF2, a guanine nucleotide exchange factor that activates the small GTPase RAP1

  4. JAM-A (show F11R Proteins) regulates epithelial permeability via association with ZO-2 (show TJP2 Proteins), afadin, and PDZ-GEF1 to activate Rap2c (show RAP2C Proteins) and control contraction of the apical cytoskeleton.

  5. NEDD4-1 (show NEDD4 Proteins) regulates cell migration and invasion through ubiquitination of CNrasGEF in vitro.

  6. We report that in response to factors that promote cell motility, the Rap guanine exchange factor RAPGEF2 is rapidly phosphorylated by I-kappa-B-kinase-beta and casein kinase-1alpha and consequently degraded by the proteasome.

  7. Data indicate that expression of Rapgef2 in embryonic kidney 293T cells enables cAMP-Rap1 (show RABGEF1 Proteins)-ERK (show EPHB2 Proteins) signaling.

  8. DNA methylation (show HELLS Proteins) shows genome-wide association of NFIX (show MLZE Proteins), RAPGEF2 and MSRB3 (show MSRB3 Proteins) with gestational age at birth.

  9. PDZ-GEF activates Rap1 under resting conditions to stabilize cell-cell junctions and maintain basal integrity

  10. Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase

Mouse (Murine) Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) interaction partners

  1. The essential role of RA-GEF-1 is the proper formation of the cerebral midline commissures.

  2. Rapgef2 deficiency led to embryonic lethality at E11.5 due to severe yolk sac (show ADCY10 Proteins) vascular defects.

  3. Our findings suggest a crucial function of RA-GEF-1 in neural migration

  4. CNrasGEF regulates melanogenesis but that it also has a distinct role in regulating cell proliferation/apoptosis

  5. These results suggest that deficient Rap1 (show TERF2IP Proteins) signaling may lead to defective vascular morphogenesis in the yolk sac (show ADCY10 Proteins) and embryos proper.

  6. the role of RA-GEF-1 in embryonic vascular network formation was investigated.

RAPGEF2 Protein Profile

Protein Summary

Members of the RAS (see HRAS\; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000

Alternative names and synonyms associated with RAPGEF2

  • Rap guanine nucleotide exchange factor (GEF) 2 (RAPGEF2)
  • Rap guanine nucleotide exchange factor (GEF) 2 (rapgef2)
  • Rap guanine nucleotide exchange factor (GEF) 2 (Rapgef2)
  • 5830453M24Rik protein
  • CNRasGEF protein
  • fa11h07 protein
  • MGC83978 protein
  • mKIAA0313 protein
  • nRap GEP protein
  • nRapGEP protein
  • PDZ-GEF1 protein
  • Pdzgef1 protein
  • RA-GEF protein
  • RA-GEF-1 protein
  • Rap-GEP protein
  • RAPGEF2 protein
  • wu:fa11h07 protein

Protein level used designations for RAPGEF2

Rap guanine nucleotide exchange factor (GEF) 2 , rap guanine nucleotide exchange factor 2 , Rap guanine nucleotide exchange factor 2-like , rap guanine nucleotide exchange factor 2-like , PDZ domain containing guanine nucleotide exchange factor (GEF) 1 , PDZ domain-containing guanine nucleotide exchange factor 1 , RA(Ras/Rap1A-associating)-GEF , neural RAP guanine nucleotide exchange protein

GENE ID SPECIES
422418 Gallus gallus
447229 Xenopus laevis
461577 Pan troglodytes
482670 Canis lupus familiaris
557693 Danio rerio
704717 Macaca mulatta
100069003 Equus caballus
100139484 Bos taurus
100145659 Xenopus (Silurana) tropicalis
100224541 Taeniopygia guttata
100346752 Oryctolagus cuniculus
100388886 Callithrix jacchus
100549357 Meleagris gallopavo
100594311 Nomascus leucogenys
9693 Homo sapiens
76089 Mus musculus
310533 Rattus norvegicus
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