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Browse our anti-Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) Antibodies

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anti-Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) Antibodies (SMPD2)
On www.antibodies-online.com are 46 Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) Antibodies from 12 different suppliers available. Additionally we are shipping Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) Kits (9) and Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) Proteins (5) and many more products for this protein. A total of 63 Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) products are currently listed.
Synonyms:
AW108287, ISC1, NSMASE, NSMASE1, SMPD2
list all antibodies Gene Name GeneID UniProt
SMPD2 20598 O70572
SMPD2 83537 Q9ET64
SMPD2 6610 O60906

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Most Popular Reactivities for anti-Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) Antibodies

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All available anti-Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) Antibodies

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Top referenced anti-Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) Antibodies

  1. Cow (Bovine) Polyclonal SMPD2 Primary Antibody for WB - ABIN2782209 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 references for ABIN2782209

  2. Human Polyclonal SMPD2 Primary Antibody for FACS, WB - ABIN650737 : Tani, Hannun: Neutral sphingomyelinase 2 is palmitoylated on multiple cysteine residues. Role of palmitoylation in subcellular localization. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for ABIN650737

  3. Human Monoclonal SMPD2 Primary Antibody for IHC (p), ELISA - ABIN562924 : Lee, Tan, Venkatratnam, Tan, Cui, Loh, Griffith, Tannenbaum, Chan: Dysregulated sphingolipid metabolism in endometriosis. in The Journal of clinical endocrinology and metabolism 2014 (PubMed)

More Antibodies against Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) Interaction Partners

Zebrafish Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) interaction partners

Mouse (Murine) Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) interaction partners

  1. cells deficient in acid ceramidase (aCDase (show ASAH1 Antibodies)) also exhibited defects in CCL5 (show CCL5 Antibodies) induction, whereas cells deficient in sphingosine kinase-1 (show SPHK1 Antibodies) and -2 exhibited higher levels of CCL5 (show CCL5 Antibodies).

  2. nSMase2 (show SMPD3 Antibodies) has a role in ceramide generation, aberrant apoptosis, and lung injury under cigarette smoke exposure

  3. Neutral sphingomyelinase 1 deficiency in the mouse causes no lipid storage disease. (nSMase 1)

  4. NSMase-2 could be involved in IL-1beta (show IL1B Antibodies)-induced JNK (show MAPK8 Antibodies) activation in hepatocytes

  5. Nuclear sphingomyelin-synthase and protein kinase C delta (show PKCd Antibodies) are expressed in melanoma cells

  6. Acid and neutral sphingomyelinase, ceramide synthase, and acid ceramidase (show ASAH1 Antibodies) have roles in cutaneous aging

  7. Peptidoglycan activates the nSMase/ceramide pathway to induce MKK3 (show MAP2K3 Antibodies)/6/p38 MAPK (show MAPK14 Antibodies) activation, which in turn initiates NF-kappaB (show NFKB1 Antibodies) activation and ultimately induces COX-2 (show COX2 Antibodies) expression in macrophages.

Human Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) interaction partners

  1. Interestingly, neutral but not acid sphingomyelinase (show SMPD1 Antibodies) was mandatory for PorBIA -mediated Neisseria gonorrhoeae invasion into host cells.

  2. nSMase1 (sphingomyelin phosphodiesterase 2, SMPD2)has a common central role in ceramide signaling during the stress and cytokine responses and apoptosis.

  3. These data suggest that Ox-LDL activates N-SMase-ceramide signaling pathway, and stimulates phosphorylation of p38 MAPK (show MAPK14 Antibodies), leading to apoptosis in vascular smooth muscle cells, which initiates VSMC calcification.

  4. cells deficient in acid ceramidase (aCDase (show ASAH1 Antibodies)) also exhibited defects in CCL5 (show CCL5 Antibodies) induction, whereas cells deficient in sphingosine kinase-1 (show SPHK1 Antibodies) and -2 exhibited higher levels of CCL5 (show CCL5 Antibodies).

  5. nSMase2 (show SMPD3 Antibodies) has a role in ceramide generation, aberrant apoptosis, and lung injury under cigarette smoke exposure

  6. N-SMase at the cytofacial plasma membrane is an essential element for the proper orientation of PMNs in FMLP (show FPR1 Antibodies) gradients, at least in part by polarizing the distribution of Rac 1/2 and RhoA (show RHOA Antibodies) GTPases.

  7. Results demonstrate that WithaD enhance the ceramide accumulation by activating N-SMase 2, modulate phosphorylation of the JNK (show MAPK8 Antibodies) and p38MAPK (show MAPK14 Antibodies) and induced apoptosis in both myeloid and lymphoid cells along with primary cells derived from leukemia patients.

  8. Data show DA remarkably increased the NSMase2 (show SMPD3 Antibodies) message and protein, whereas little change in NSMase1 and NSMase3 (show SMPD4 Antibodies) mRNAs.

  9. nSMase2 (show SMPD3 Antibodies) functions as a growth suppressor in MCF7 cells, linking confluence to the G(0)/G(1) cell cycle check point.

  10. identification of 15 polymorphisms, including 9 novel SNPs, in the SMPD2 gene; one haplotype showed associations with the extrinsic type of atopic dermatitis subgroup

Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2) Antigen Profile

Antigen Summary

This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase.

Alternative names and synonyms associated with Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2)

  • sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) (SMPD2) antibody
  • sphingomyelin phosphodiesterase 2, neutral (smpd2) antibody
  • sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) (smpd2) antibody
  • sphingomyelin phosphodiesterase 2, neutral (Smpd2) antibody
  • sphingomyelin phosphodiesterase 2, neutral membrane (Smpd2) antibody
  • AW108287 antibody
  • ISC1 antibody
  • NSMASE antibody
  • NSMASE1 antibody
  • SMPD2 antibody

Protein level used designations for SMPD2

sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) , Mg2+-dependent neutral sphingomyelinase , neutral SMase I , neutral sphingomyelinase , sphingomyelin phosphodiesterase 2 , sphingomyelin phosphodiesterase 2-like , N-SMase , lyso-PAF-PLC , lyso-platelet-activating factor-phospholipase C , neutral sphingomyelinase 1

GENE ID SPECIES
462928 Pan troglodytes
567548 Danio rerio
698865 Macaca mulatta
770663 Gallus gallus
100145256 Xenopus (Silurana) tropicalis
100394711 Callithrix jacchus
100455395 Pongo abelii
100479011 Ailuropoda melanoleuca
100512027 Sus scrofa
100604925 Nomascus leucogenys
20598 Mus musculus
83537 Rattus norvegicus
6610 Homo sapiens
481957 Canis lupus familiaris
509018 Bos taurus
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