The cytoskeleton is a complex organizational nexus that provides far more than just structural support for the cell. While its name may imply a rigid and immutable structure, the cytoskeleton is actually a dynamic interconnected network of filamentous proteins interacting with hundreds of different molecular motors, cross-linkers, and cargo containing vesicles.
Independent Validation

Independent Validation

Two more antibodies for the detection of different antigens were successfully tested in Western Blot experiments. The antibodies-online antibody for the detection of beta Catenin was tested with MCF-7 cells and SK-BR-3 cells. In MCF-7 cells a clear band was visible in the correct size of beta Catenin.

Furthermore, the antibodies-online antibody ABIN98862 for the detection of human EGFR was validated in combination with MCF-7 and A549 cells. The presence of EGFR could be clearly seen in A549 cell lysates.

Oridonin is a tetracycline diterpentoid extracted from the Chinese herb Rabidosia rubescens. Recent research suggests that oridonin displays promising anti-tumorigenic and anti-inflammatory properties both in vivo and in vitro (Zhou et al., 2007; Wang YY et al., 2014).
In a recent study published in the World Journal of Gastroenterology, Chen et al. demonstrate that oridonin treatment mediates inflammatory cytokine pathways, significantly reducing secretion of inflammatory cytokines by pancreatic cancer cells in vitro (Chen et al., 2014).
Researchers used three ELISA kits, available at antibodies-online, to measure the concentration of inflammatory cytokines: IL-33 ELISA kit (ABIN457022), IL-6 ELISA kit (ABIN365163), and IL-1B ELISA kit (ABIN365160) in culture supernatant from human pancreatic cancer (BxPC-3) cells.
In each case, oridonin treatment resulted in a marked decrease in the release of inflammatory cytokine molecules when compared to untreated (control) cells.
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