A current study investigated the effects of GluR1 in the hypothalamus, providing biochemical and cellular mechanisms which regulate food intake. The study utilized an anti-phospho-Ser845 and an anti-phospho-Ser831 GluR1 antibody which are available on antibodies-online.  » Read more

This years' conference on Clinical Trials in CNS, is taking place on the 15th and 16th November 2010 in London, and will bring together leading industry experts to explore the current and future opportunities within CNS drug development. Representing the second largest therapeutic segment of the pharmaceutical market it is also one of the fastest growing. This year the conference aims to cover clinical drug discovery activities, new therapeutic targets, as well as effective CNS drug development strategies and problems encountered in clinical trials, with in-depth discussions and case study presentations from the key industry players.  » Read more

On antibodies-online.com you may find ELISA kits from USCN Life Science. Here you will find 24.000 USCN ELISA kits.

More than 100 antibodies have been cited in current scientific publications in the past weeks that are available on antibodies-online.com. Here you may find an overview of the cited antibodies.

BioMed Central and Malaria Journal’s conference ‘Parasite to prevention: Advances in the understanding of malaria’ will be held at Heriot-Watt University, Edinburgh, UK from 20-22 October 2010. This international conference, which brings together leading researchers and industry representatives, is where attendees will learn about the latest developments in key areas and initiatives that are at the forefront of malaria research. All participants are invited to submit abstracts for oral and poster presentations by 6 August 2010. Limited numbers of bursary places are also available. Visit www.parasitetoprevention.com for more details.

Peroxiredoxins act by reducing hydroperoxides, which naturally occur as a side-product of the photosynthetic process. A recent study utilized an anti-peroxiredoxin antibody in order to address the question of break-down of reactive oxygen species in Arabidopsis thaliana chloroplasts. Here you may find the applied »antibody against ATPRX Q. On antibodies-online a large number of additional »peroxiredoxin antibodies can be found.  » Read more

A study published this year in the Journal Oncogene addresses the expressional regulation of Bmi1 and its downstream targets. The research was carried out in neuroblastoma (NB) cells and addressed questions of epigenetic alterations and its roles in the tumorigenesis of NB. Using an antibody specific for Bmi1 it was revealed that the expression of Bmi1 resulted in the acceleration of proliferation and colony formation in NB cells.  » Read more

A recent study investigated the impact of iron deficiency on bioenergetic pathways in Chlamydomonas, a genus of green alga. The researchers found that acetate-grown iron-limited cells maintained high growth rates by suppressing photosynthesis and increasing respiration instead. In order to study this phenomenon the researcher used antibodies that are available on antibodies-online, namely an anti-plasma membrane ferroxidase (or anti-FOX1) antibody and an anti-COXII - mitochondrial cytochrome oxidase subunit II antibody.  » Read more

The 6th annual European Antibody Congress is the World’s leading conference addressing critical scientific issues and strategic industry challenges associated with therapeutic nonoclonal antibody development. Please visit the website for full programme and speaker details. www.terrapinn.com/antibodies

• New market success stories: golimumab, canakinumab, obatumumab, farletuzmab and girentuximab case studies
• For the first time on the agenda: Amgen, the FDA, Chugai Pharmaceutical Co, sanofi-aventis, Sandoz, Merrimack
• Pharmaceuticals, AdAlta, Wilex, Vaccinex and Biocon
• First ever discussion of global biosimilar antibody development and impact on the European market
• Exploring radio-immunoconjugates: scientific, technical, regulatory and logistical challenges

The research in the human plasmatic proteins field expands very rapidly. The technical challenge to analyze this proteome stems from the large quantity of plasmatic proteins. Some proteins are highly abundant, such as Human Serum Albumin (HSA), and prevent the detection of rare proteins. The depletion of HSA, by an anti-HSA antibodies, allows the detection of such rare proteins which could be medicinal targets or biological markers. This »anti-HSA antibody may be coupled to magnetic beads to be used in blood research for the depletion of HSA by applying magnetism.

In the replication of Herpes Simplex Virus (HSV)-1 glycoprotein K (gK) and the UL20 protein (UL20p) are required. A recent study in the Journal of Virology investigated the interaction of the N-terminal amino acids of gKa together with the extracellular portions of the proteins gB, gD, or gH, respectively. The study implies that the gK/UL20p protein complex directly interacts with gB and gH. The HSV gD Envelope Protein antibody that has been utilized in this study is from Firma Virusys and available at antibodies-online.  » Read more

On antibodies-online you will find Agro-Bio kits, like for example EggsPure, for the purification of IgY from eggs. Additionally, you may find trypsin that has been immobilized on magnetic beads (EnzyBeads), that allows the digest of proteins, and subsequently an easy removal-step of the trypsin simply using a magnet.

A recent study aimed to determine if there are added renoprotective benefits seen by combining angiotensin-converting enzyme-1 inhibitors (ACEi) with blockade of NADPH oxidase in antihypertensive therapies, and found that a combination of NADPH oxidase blockade with ACE inhibitors is a promising regimen. The study was performed using an ELISA kit against kidney injury molecule 1 (Kim-1).  » Read more