antibodies-online welcomes our newest supplier, AllerMAbs to our marketplace

AllerMAbs, uses proprietary knock-in mice to generate Chimeric Human antibodies against common allergens for research and sero-diagnostic use.

  • The IgE-mediated adaptive immune precedes clinical symptoms of allergy (sneezing, itching, runny nose, etc.).
  • Current standards used for detection & antigenic profiling of the IgE-mediated immune response are composed of mixed serum & plasma from human donors
  • This process of collection is labor intensive and expensive, and there is relatively low batch-to-batch consistency and questionable antigen specificity in these samples
  • AllerMAbs has pioneered a unique method of generating chimeric human monoclonal IgE antibodies through a proprietary knock-in mouse model & conventional hybridoma technology
  • The result is a universally-consistent, well-validated chimeric human IgE antibody with exceptional specificity for individual antigens.

See all AllerMAbs antibodies against allergens like Der P1 (dust mite), Ovalbumin (egg), Papain, and BetV1 (Birch pollen)

ProteoGenix is an industry leader in the production of antibodies, peptides, and recombinant proteins for life-science research and cancer diagnosis.

  • ProteoGenix materials are produced in-house. From gene synthesis, to purification of a complete immunoassay reagent (antibodies, recombinant proteins, and other reagents), each step is carefully controlled for QA at their Schiltigheim, France based facility
  • More than 330 products from ProteoGenix are available at antibodies-online, including a number of phosphospecific and methylspecific anti-Histone protein primary antibodies for studying epigenetic modification and inheritance
  • For consistent, reliable targeting of tagged fusion proteins, ProteoGenix also offers a line of highly validated IP approved antibodies targeting common epitope tags like poly-Histidine and GST

See all 334 ProteoGenix products (antibodies, recombinant proteins, and accessory reagents) now at antibodies-online!

Matrix metalloproteinases (MMP) are calcium dependent zinc-endopeptidases that can degrade extracellular matrices. They are involved in tissue remodeling and play an important role in cell proliferation and migration, differentiation, and apoptosis. Uncontrolled expression and activity on the other hand is documented in various neurological disorders (including Parkinson's and Alzheimer's disease), rheumatoid arthritis, and cancer metastases. MMP activity must therefore be tightly regulated by tissue inhibitors of metalloproteinases (TIMP).

Antibodies-online has added new antibodies against several human MMPs tested for various applications. Please check out these and other products in our catalog and don't hesitate to get in touch with one of our customer service agents if you have any questions.

Cytochrome P450 (CYP) hemoproteins constitute a family of isozymes that transform a wide variety of drugs. Due to their omnipresence in virtually all tissues they have emerged as an important determinant in adverse drug interactions.

antibodies-online offers a number of isoform-specific Cytochrome P450 Assays. These assays measure Cytochrome P450 enzyme activity in cells, tissues and membrane fractions. Cytochrome P450 is a major target for drug development.

Below you may find a list of Cytochrome P450 Assays by isoform.

Now it's easier than ever to screen for PD-1 pathway inhibitors

The ACROBiosystems PD-1 inhibitor assay at antibodies online is a simple and efficient way to identify screen for PD-1 pathway inhibitors.

Activation of PD-1 by its ligand PD-L1 suppresses autoimmunity by preventing inappropriate activation of T-cells. Tumors frequently subvert this mechanism to avoid immune surveillance, and PD-1 pathway inhibitors have shown some promise as anti-cancer therapeutic agents.