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Studying Drug Metabolism: Cytochrome P450 Assays

Cytochrome P450 (CYP) hemoproteins constitute a family of isozymes that transform a wide variety of drugs. Due to their omnipresence in virtually all tissues they have emerged as an important determinant in adverse drug interactions.

antibodies-online offers a number of isoform-specific Cytochrome P450 Assays. These assays measure Cytochrome P450 enzyme activity in cells, tissues and membrane fractions. Cytochrome P450 is a major target for drug development.

Below you may find a list of Cytochrome P450 Assays by isoform.


Target Assay Kit ELISA Kit Inhibitor Screening Kit
Cytochrome P450 1A2 (CYP1A2) CYP1A2 Activity Assay Kit (Fluorometric) CYP1A2 ELISA Kit CYP1A2 Inhibitor Screening Kit (Fluorometric)
Cytochrome P450 2C19 (CYP2C19) CYP2C19 Activity Assay Kit (Fluorometric) - CYP2C19 Inhibitor Screening Kit (Fluorometric)
Cytochrome P450 2C9 (CYP2C9) - CYP2C19 ELISA Kit -
Cytochrome P450 2D6 (CYP2D6) CYP2D6 Activity Assay Kit (Fluorometric) CYP2D6 ELISA Kit CYP2D6 Inhibitor Screening Kit (Fluorometric)
Cytochrome P450 3A4 (CYP3A4) CYP3A4 Activity Assay Kit (Fluorometric) CYP3A4 ELISA Kit (Human), CYP3A4 ELISA Kit (Mouse) CYP3A4 Inhibitor Screening Kit (Fluorometric)
Cytochrome P450 Reductase (CPR) Cytochrome P450 Reductase (CPR) Activity Assay Kit Cytochrome P450 Reductase (CPR) ELISA Kit (Human), Cytochrome P450 Reductase (CPR) ELISA Kit (Rat) -

Also of interest: Microsome Isolation Kit

Validation data for CYP3A4 Assays

Validation data for CYP3A4 Assays

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