You are viewing an incomplete version of our website. Please click to reload the website as full version.

Antibodies against Cytomegalovirus (CMV)

Image for CMV ICP36 antibody
The human Cytomegalovirus (HCMV) is a Herpes virus and belongs to the Betaherpesvirinae family. In general members of this family have a limited host range, expand slower in cell culture and have a longer growth cycle compared to Herpes Simplex Virus. HCMV infections are often located in salivary glands. In combination with a weak immune system HCMV infections can be lethal. The following antibodies are being used frequently in current publications for detecting HCMV: Cytomegalovirus ICP36 antibody (CH16), Cytomegalovirus ICP36 DNA Binding Protein (CMV ICP36) antibody and Cytomegalovirus UL84 (CMV UL84) antibody. A list of current publications is available here:

Cytomegalovirus ICP36 DNA Binding Protein (CMV ICP36) Antikörper

Sofia Hamirally et al. (2009) Viral Mimicry of Cdc2/Cyclin-Dependent Kinase 1 Mediates Disruption of Nuclear Lamina during Human Cytomegalovirus Nuclear Egress. PLoS Pathog. 2009 January; 5(1): e1000275. »Show publication

Marisa K. Isaacson and Teresa Compton. (2009) Human Cytomegalovirus Glycoprotein B Is Required for Virus Entry and Cell-to-Cell Spread but Not for Virion Attachment, Assembly, or Egress. Journal of Virology, April 2009, p. 3891-3903, Vol. 83, No. 8. »Show publication

Emily E. Marshall et al. (2009) Essential role for either TRS1 or IRS1 in human cytomegalovirus replication. J. Virol. doi:10.1128/JVI.02489-08»Show publication

Zhikang Qian et al. (2008) The Full-Length Protein Encoded by Human Cytomegalovirus Gene UL117 Is Required for the Proper Maturation of Viral Replication Compartments. Journal of Virology, April 2008, p. 3452-3465, Vol. 82, No. 7. »Show publication

Blair L Strang et al. (2009) Analysis of the Association of the Human Cytomegalovirus DNA Polymerase Subunit UL44 with the Viral DNA Replication Factor UL84. J. Virol. doi:10.1128/JVI.00663-09.»Show publication

Cytomegalovirus ICP36 Antikörper (CH16)

Anokhi J. Kapasi et al. (2009) Recruitment of CDK9 to the Immediate Early Viral Transcriptosomes during Human Cytomegalovirus Infection requires efficient Binding to Cyclin T1, a Threshold Level of IE2 86, and Active Transcription. J. Virol. doi:10.1128/JVI.02651-08. »Show publication

Rebecca L. Sanders et al. (2008) Development of Cell Lines That Provide Tightly Controlled Temporal Translation of the Human Cytomegalovirus IE2 Proteins for Complementation and Functional Analyses of Growth-Impaired and Nonviable IE2 Mutant Viruses. Journal of Virology, July 2008, p. 7059-7077, Vol. 82, No. 14. »Show publication

Rebecca L. Sanders et al. (2008) Internal Deletions of IE2 86 and Loss of the Late IE2 60 and IE2 40 Proteins Encoded by Human Cytomegalovirus Affect the Levels of UL84 Protein but Not the Amount of UL84 mRNA or the Loading and Distribution of the mRNA on Polysomes. Journal of Virology, November 2008, p. 11383-11397, Vol. 82, No. 22. »Show publication

Elizabeth A. White et al. (2007) The IE2 60 kDa and 40 kDa Proteins are Dispensable for Human Cytomegalovirus Replication, but are Required for Efficient Delayed Early and Late Gene Expression and Production of Infectious Virus. J. Virol. doi:10.1128/JVI.02454-06. »Show publication

Cytomegalovirus UL84 (CMV UL84) Antikörper

Kelly S. Colletti et al. (2004) Human cytomegalovirus UL84 oligomerization and heterodimerization domains act as transdominant inhibitors of oriLyt-dependent DNA replication: evidence that IE2-UL84 and UL84-UL84 interactions are required for lytic DNA replication. J Virol. 2004 Sep;78(17):9203-14. »Show publication

Kelly S. Colletti et al. (2007) Human Cytomegalovirus UL84 Interacts with an RNA Stem-Loop Sequence Found within the RNA/DNA Hybrid Region of oriLyt. Journal of Virology, July 2007, p. 7077-7085, Vol. 81, No. 13. »Show publication

Yang Gao et al. (2008) Identification of Human Cytomegalovirus UL84 Virus- and Cell-Encoded Binding Partners by Using Proteomics Analysis. Journal of Virology, January 2008, p. 96-104, Vol. 82, No. 1. »Show publication

Rebecca L. Sanders et al. (2008) Development of Cell Lines That Provide Tightly Controlled Temporal Translation of the Human Cytomegalovirus IE2 Proteins for Complementation and Functional Analyses of Growth-Impaired and Nonviable IE2 Mutant Viruses. Journal of Virology, July 2008, p. 7059-7077, Vol. 82, No. 14. »Show publication

Rebecca L. Sanders et al. (2008) Internal Deletions of IE2 86 and Loss of the Late IE2 60 and IE2 40 Proteins Encoded by Human Cytomegalovirus Affect the Levels of UL84 Protein but Not the Amount of UL84 mRNA or the Loading and Distribution of the mRNA on Polysomes. Journal of Virology, November 2008, p. 11383-11397, Vol. 82, No. 22. »Show publication

Elizabeth A. White et al. (2007) The IE2 60 kDa and 40 kDa Proteins are Dispensable for Human Cytomegalovirus Replication, but are Required for Efficient Delayed Early and Late Gene Expression and Production of Infectious Virus. J. Virol. doi:10.1128/JVI.02454-06. »Show publication

More antibodies against CMV are available here:

All antibody for the research area are listed here: