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Y-box Protein-1 (YB-1): Monoclonal antibody detects nuclear YB-1

In a recent BMC Cancer article Peter R. Mertens et al show that the monoclonal anti-YB-1 antibody F-E2G5 detects nuclear . The nuclear localisation of is associated with a poor survival rate. In addition a correlation between nuclear and the abscence of progesterone receptor expression was uncovered. This correlation could indicate that the nuclear localisation of is characteristic for a specific breast cancer subtype. For this study 179 breast cancer samples were analysed using immunohistochemistry (Paraffin-embedded sections). »Show datasheet & publication reference