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Superior quality antibody: hsc70 (hsp-like) antibody frequently cited

Area: Heat Shock Proteins
Image: hsp70 antibody ABIN361801
Heat shock proteins (HSP) support the maintenance of three dimensional structures of proteins for instance by protecting them from denaturation due to heat. They can be found everywhere in the organism and are expressed extensively, for example, under stress condition caused by exposure to high heat, UV-rays or ethanol.
Hsp70 genes encode abundant heat-inducible 70-kDa hsps. In most eukaryotes hsp70 genes are part of a multigene family. They exist in most cellular compartments of eukaryotes, like nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, and have at least 50% homogeneity.

This mouse monoclonal hsc70-antibody is reactive against Human, Mouse (Murine) and Rat hsc70 (hsp70 is highly related to hsc70, >90% sequence identity), and has been tested for Western Blot, ELISA, immunoprecipitation and immunohistochemistry.

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Source:

1. Brown C.L. et al. (1993) J.Cell Biol., 120 (5): 1101- 1112

2. Boorstein W.R., Ziegelhoffer T., and Craig E.A. (1993) J. Mol. Evol. 38(1): 1-17.

3. Rothman J. (1989), Cell 59: 591-601.

4. DeLuca-Flaherty et al. (1990) Cell 62: 875-887.

5. Bork P., Sander C., and Valencia A. (1992) Proc. Nut1 Acad. Sci. USA 89: 7290-7294.

6. Brown C.L. et al. (1996) J. Biol. Chem. 271(2): 833- 840

09.03.2010 | David Kitz Kramer   RSS Feed   New Antibodies   Bookmark and Share

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