The cell cycle of eukaryotic cells consists of various phases. Two of them can be identified morphologically and biochemically. The first phase that can be distinguished happens during cell mitosis (M-phase), in which the cell divides into two identical daughter cells; chromosome condensation and spindle formation are microscopically visible. The second discernible phase is the S-phase where the DNA of a cell is replicated. Antibodies recognizing the phases of the cell cycle are of value for example in cancer research.

The mouse-monoclonal 8B3G antibody strongly stains human mitotic cells and can therefore be used in flow cytometric analyses of cell suspensions. It can also be applied in immunocytochemistry and immunohistochemistry.

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