The forkhead (named after the Drosophila melanogaster gene fork head) gene family comprises a diverse group of 'winged-helix' (called after its butterfly-like shape) transcription factors that play important roles in development, Metabolism, Cancer, ageing and speech development in humans.

Forkhead box protein N1 , the product of the FOXN1 gene (in humans) has severe effects when mutated, i.e. it has been correlated with T-cell immunodeficiency, congenital alopecia, and nail dystrophy. Expectedly, in adult mammals it is being expressed in epithelial thymus cells, as well as in certain cells of the hair follicle. Mutations in the rodent orthologue result in similar defects as in humans, and leads to the so-called nude phenotype in mice.

This high quality polyclonal goat anti-human Forkhead box protein N1 antibody has been tested for ELISA and Immunohistochemistry. This antibody has been purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

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