You are viewing an incomplete version of our website. Please click to reload the website as full version.
Area: , ,

Osteocalcin: Bone marker has role in glucose metabolism

A superior quality sheep antiserum against Osteocalcin can be ordered from antibodies-online.com. The peptide-hormone which has been discovered in 1975 is active in bone and teeth of most vertebrates. It binds hydroxylapatite and calcium, and is part of the extracellular non-collagenous bone-matrix. is an inhibitor of bone mineralisation, and also reveals additional surprising functions

A study in the journal Cell, published in 2007, reveals the connection of with glucose metabolism. In mice even small amounts of trigger insulin release and reduction of adipose cells. The antiserum against Osteocalcin offered by antibodies-online.com is well-suited for detection of this marker of bone growth.
Source: Na Kyung Lee, Hideaki Sowa, Eiichi Hinoi, Mathieu Ferron, Jong Deok Ahn, Cyrille Confavreux, Romain Dacquin, Patrick J. Mee, Marc D. McKee, Dae Young Jung, Zhiyou Zhang, Jason K. Kim, Franck Mauvais-Jarvis, Patricia Ducy, and Gerard Karsenty, "Endocrine Regulation of Energy Metabolism by the Skeleton."
Cell 130(2007): 456-469.