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Hot research topic: The Solute Carrier Proteins (SLC)
Area: Signaling, Transporters
Pharmaceutical companies are getting increasingly interested in the solute carrier (SLC) protein family.
Several are active in the blood brain barrier and are being investigated as potential aids for drugs delivery by allowing new drugs to mimic the specific solutes.
Examples are SLC7A6 involved in amino acid transport, SLC2A1 involved in hexose (glucose) transport, SLCO1B1 involved in transport of organic anions and opioids, SLC6A8 involved in transport of brain creatine, etc.
Protein SLC6A4 for instance is a strong candidate as a drug target, because it is a serotonin transporter that removes the neurotransmitter from the synaptic cleft and thus terminating its function.
The solute carrier (SLC) proteins constitute a group of membrane-integrated transporters. Solutes that are transported by the various SLC group members are extraordinarily diverse and include both charged and uncharged organic molecules as well as inorganic ions. Below are several examples of SLCs that are being offered on antibodies-online.com
The solute carrier (SLC) proteins constitute a group of membrane-integrated transporters. Solutes that are transported by the various SLC group members are extraordinarily diverse and include both charged and uncharged organic molecules as well as inorganic ions. Below are several examples of SLCs that are being offered on antibodies-online.com
| Antibodies against Solute Carrier Proteins (SLC) | ||
| Order Number | Antigen | Applications |
| ABIN185672 | GLUT8 / SLC2A8 | ELISA |
| ABIN238576 | KCC1 / SLC12A4 | ELISA, Western Blotting (WB) |
| ABIN238578 | KCC3 / SLC12A6 | ELISA, Western Blotting (WB) |
| ABIN238577 | KCC4 / SLC12A7 | ELISA |
| ABIN185496 | SLC9A3R2 (isoform A3) | ELISA, Western Blotting (WB), Immunohistochemistry (IHC) |
| ABIN335162 | Slc10a2 (mouse) | ELISA, Western Blotting (WB) |
| ABIN184612 | SLC16A7 / MCT2 | ELISA, Western Blotting (WB) |
| ABIN334492 | SLC22A16 | ELISA |
| ABIN335163 | SLC22A17 | ELISA |
| ABIN185638 | SLC24A5 | ELISA, Western Blotting (WB) |
| ABIN335164 | SLC26A5 / prestin | ELISA |
| ABIN185394 | SLC6A4 / 5HTT / SERT | ELISA, Western Blotting (WB) |
| ABIN190899 | SLC7A11 | ELISA, Western Blotting (WB) |
| ABIN185512 | UCP1 | ELISA, Western Blotting (WB) |
| ABIN190824 | Uncoupling protein 2 / UCP2 | ELISA, Western Blotting (WB) |
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