A recent study investigated the feasibility of sodium lauryl sulfoacetate (SLS) as an immunoadjuvant in chickens as well as the outcome of a combination of SLS and the immunosuppressant thiamphenicol.
Chickens were vaccinated with a vaccine against Newcastle disease virus and the immunoadjuvant effects of SLS were evaluated on the basis of T-cell ratio of CD4 to CD8 amongst others. For this FITC conjugated anti-CD4
and biotin conjugated anti-CD3
antibodies were utilized that can be purchased from antibodies-online.
The study showed that SLS improved the humoral immune response and reversed the immunosuppressive effect of thiamphenicol in chickens.